成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List 1-BROMOMETHYL-ISOQUINOLINE
74417-44-0

1-BROMOMETHYL-ISOQUINOLINE synthesis

3synthesis methods
-

Yield:74417-44-0 18%

Reaction Conditions:

with N-Bromosuccinimide;2,2'-azobis(isobutyronitrile) in tetrachloromethane; for 2 h;Heating / reflux;

Steps:

17-1

Preparation 17-1); 1-Bromomethyl-isoquinolineTo 1-methylisoquinoline (0.99 g, 6.91 mmol), NBS (1.35 g, 1.1 eq) and AIBN(IO mg, catalytic amount) was added CCl4 (IS mL), which was then refluxed for 2 h. The suspended particles were removed by filtration, and washed with CCl4. The organic layers were combined, concentrated under reduced pressure, and separated by column chromatography (30%, ethyl acetate/hexane) to give the title compound (270 mg, Yield: 18%) as a violet solid.1H-NMR (500MHz, CDCl3) δ 8.48(d, IH), 8.25(d, IH), 7.87(d, IH),7.75-7.67(two t, 2H), 7.65(d, IH)

References:

WO2008/16239,2008,A1 Location in patent:Page/Page column 57-58