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ChemicalBook CAS DataBase List 1-Bromo-2,4-difluorobenzene
348-57-2

1-Bromo-2,4-difluorobenzene synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 94 percent / butyllithium; bromine / hexane; tetrahydrofuran / 0.75 h / -75 °C
2: diisopropylamine; butyllithium / hexane; tetrahydrofuran / 2 h / -75 °C

References:

Schlosser, Manfred;Heiss, Christophe [European Journal of Organic Chemistry,2003,# 23,p. 4618 - 4624]

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