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758709-48-7

1-ADAMANTAN-1-YL-4,4,4-TRIFLUORO-BUTANE-1,3-DIONE synthesis

2synthesis methods
-

Yield:-

Reaction Conditions:

Stage #1: 1-acetyladamantanewith lithium hexamethyldisilazane in tetrahydrofuran at 0 - 20; for 0.333333 h;
Stage #2: 2,2,2-trifluoroethyl trifluoroacetate in tetrahydrofuran at 20; for 0.333333 h;
Stage #3: with ammonium chloride in tetrahydrofuran;water;

References:

Riofski, Mark V.;John, Jinu P.;Zheng, Mary M.;Kirshner, Julia;Colby, David A. [Journal of Organic Chemistry,2011,vol. 76,# 10,p. 3676 - 3683] Location in patent:experimental part

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