Yield:73898-23-4 70%

Reaction Conditions:

with potassium hydrogensulfate;isoquinolinium dichromate;potassium iodide in water at 20;Sonication;Reagent/catalyst;Temperature;

Steps:

General Procedure for Ultrasonically Assisted Halogenation Reactions

General procedure: The general method for ultrasonically assisted brominationreaction is almost similar to conventional reaction as mentionedabove. A centimolar (0.01 mol) organic substrate (phenols,anilines, or acetanilides), 0.001 mol potassium halide(KBr), about 50 mg of dilute KHSO4, and hypervalent Cr(VI) reagent (IQCC or IQDC) were suspended in about30 mL solvent (DCE or ACN) in a previously cleaned roundbottom(R.B) flask placed in a sonicator. The reaction mixtureis sonicated at room temperature about 30-40 min. Progressof the reaction was monitored by TLC technique. Workupprocedure after completion of the reaction mixture is similarto the one described previously.

References:

Rao, A. Sambashiva;Rajanna;Reddy, K. Rajendar;Kulkarni, Subhash [Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry,2016,vol. 46,# 6,p. 832 - 837]