ChemicalBook CAS DataBase List 1,10-PHENANTHROLINE-2,9-DICARBOXYLIC ACID

1,10-PHENANTHROLINE-2,9-DICARBOXYLIC ACID synthesis

4synthesis methods

Product Name:1,10-PHENANTHROLINE-2,9-DICARBOXYLIC ACID
CAS Number:57709-61-2
Molecular formula:C14H8N2O4
Molecular Weight:268.22

1,10-Phenanthroline, 2,9-bis(trichloromethyl)-

78831-41-1
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1,10-PHENANTHROLINE-2,9-DICARBOXYLIC ACID

57709-61-2
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$23.00/250mg

Yield: 100%

Reaction Conditions:

with sulfuric acid in water at 85; for 7 h;

Steps:

1,10-Phenanthroline-2,9-dicarboxylic acid (3)
A solution of 2 (540 mg, 1.3 mmol, 1.0 equiv) in concentratedaqueous sulfuric acid (95-98%, 17 mL) was stirred at 85 °C for 7h. Following this, the brown solution was cooled to room temperatureand poured over crushed ice. The ice was allowed tomelt and the resulting white suspension filtered under vacuum,washed with water, and air-dried to afford pure compound 3(360 mg, quant. yield). 1H NMR (300 MHz, DMSO-d6): δ = 8.22(s, 2 H), 8.42 (d, 3J = 8.4 Hz, 2 H), 8.74 (d, 3J = 8.4 Hz, 2 H); mp215-216 °C (dec.).

References:

Miron, Caitlin E.;Petitjean, Anne [Synlett,2018,vol. 29,# 10,p. 1362 - 1366]