ChemicalBook CAS DataBase List 1,1,3-TRIMETHOXYPROPANE

1,1,3-TRIMETHOXYPROPANE synthesis

13synthesis methods

Product Name:1,1,3-TRIMETHOXYPROPANE
CAS Number:14315-97-0
Molecular formula:C6H14O3
Molecular Weight:134.17

1,1,3-TriMethoxypropane can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly in laboratory research and development process. It was synthesized from Methanol mixed with glycerol (4 :1 ) reacted under ZrO2/SO42- super acid catalyst for 4.3 minutes at 200° C(0.1 psia (5 mm Hg)).

67-56-1 Synthesis

67-56-1
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56-81-5 Synthesis

56-81-5
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14315-97-0
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$45.79/5g

Yield: 21.8%

Reaction Conditions:

ZrO₂/SO₄^2- super acid catalyst at 20 - 200; under 5 Torr; for 0.0716667 h;Product distribution / selectivity;

Steps:

2
Methanol was mixed with glycerol at a ratio of 4 to 1 by weight at ambient temperature. The mixture was pumped to a reactor packed with ZrO₂/SO₄^2- super acid catalyst synthesized as above. The reactor temperature was maintained at 200° C. and the reactor pressure was maintained at 0.1 psia (5 mm Hg). The reaction time (residence time based on the reactor volume/liquid feed rate) was 4.3 minutes. The glycerol in the feed was almost completely consumed, and the methanol consumed was 28.9 wt. % of the input. The products and other details are shown in Table 2 below:

References:

HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF NATURAL RESOURCES US2010/16641, 2010, A1 Location in patent:Page/Page column 3

67-56-1 Synthesis

67-56-1
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$7.29/5ml-f