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ChemicalBook >> CAS DataBase List >> neoantimycin

neoantimycin

neoantimycin price.
  • $328 - $631
  • Product name: neoantimycin
  • CAS: 22862-63-1
  • MF: C36H46N2O12
  • MW: 698.76
  • EINECS:
  • MDL Number:MFCD11111613
  • Synonyms:neoantimycin;N-(15-Benzyl-10-sec-butyl-14-hydroxy-3-isopropyl-7,13,13-trimethyl-2,5,9,12-tetraoxo-1,4,8,11-tetraoxacyclopentadeca-6-yl)-3-formylamino-2-hydroxybenzamide;Benzamide, 3-(formylamino)-2-hydroxy-N-[(3S,6S,7R,10S,14R,15R)-14-hydroxy-7,13,13-trimethyl-3-(1-methylethyl)-10-[(1S)-1-methylpropyl]-2,5,9,12-tetraoxo-15-(phenylmethyl)-1,4,8,11-tetraoxacyclopentadec-6-yl]-
5 prices
Selected condition：
Brand
  • Cayman Chemical
  • TRC
  • Usbiological
Package
  • 500ug
  • 500μg
  • 1mg
  • 1000μg
  • ManufacturerCayman Chemical
  • Product number23645
  • Product descriptionNeoantimycin >98%
  • Packaging500μg
  • Price$328
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23645
  • Product descriptionNeoantimycin >98%
  • Packaging1mg
  • Price$464
  • Updated2023-01-06
  • Buy
  • ManufacturerTRC
  • Product numberN389908
  • Product descriptionNeoantimycin
  • Packaging1000μg
  • Price$475
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number460646
  • Product descriptionNeoantimycin
  • Packaging500μg
  • Price$631
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product numberN1011
  • Product descriptionNeoantimycin
  • Packaging500ug
  • Price$523
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 23645 Neoantimycin >98% 500μg $328 2024-03-01 Buy
Cayman Chemical 23645 Neoantimycin >98% 1mg $464 2023-01-06 Buy
TRC N389908 Neoantimycin 1000μg $475 2021-12-16 Buy
Usbiological 460646 Neoantimycin 500μg $631 2021-12-16 Buy
Usbiological N1011 Neoantimycin 500ug $523 2021-12-16 Buy

Properties

Boiling point :930.3±65.0 °C(Predicted)
Density :1.29±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form :White to off-white solid.
pka :7.24±0.50(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Neoantimycin is a macrocyclic antibiotic isolated from Streptomyces bacteria. The mechanism of action of Neoantimycin is undescribed in the literature. A closely related compound described as an oxidized-type neoantimycin, prunustatin A, is demonstrated to downregulate grp78 transcription and suppress the expression of the GRP 78 molecular chaperone. This suppression affects the role of GRP 78 in promoting protein folding at the endoplasmic reticulum (ER), and suppresses the pro-resistance enhancement of ER stress response by chemotherapy-resistant tumors. The close structural kinship between prunustatin A and Neoantimycin suggests a similar mechanism of action for Neoantimycin toxicity.

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