YK-4-279
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- $35 - $1853.5
- Product name: YK-4-279
- CAS: 1037184-44-3
- MF: C17H13Cl2NO4
- MW: 366.2
- EINECS:
- MDL Number:MFCD18382120
- Synonyms:YK-4-279;4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one;4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one YK-4-279;YK-4-279;YK 4-279;4,7-dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1H-indol-2-one;CS-1785;2H-Indol-2-one, 4,7-dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-;YK-4-279 USP/EP/BP
27 prices
Brand
- AK Scientific
- Alichem
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Tocris
- TRC
Package
- 5mg
- 10MG
- 50mg
- 1MG
- 50
- 10
- 10mM(in 1mL DMSO)
- 100mg
- 250mg
- 500mg
- 1g
- ManufacturerAK Scientific
- Product numberSYN5754
- Product descriptionYK-4-279
- Packaging100mg
- Price$567
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number1037184443
- Product description4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one
- Packaging250mg
- Price$714
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number1037184443
- Product description4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one
- Packaging500mg
- Price$960.4
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number1037184443
- Product description4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one
- Packaging1g
- Price$1853.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008897
- Product description4,7-DICHLORO-1,3-DIHYDRO-3-HYDROXY-3-(2-(4-METHOXYPHENYL)-2-OXOETHYL)-2H-INDOLE-2-ONE 95.00%
- Packaging10MG
- Price$484
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008897
- Product description4,7-DICHLORO-1,3-DIHYDRO-3-HYDROXY-3-(2-(4-METHOXYPHENYL)-2-OXOETHYL)-2H-INDOLE-2-ONE 95.00%
- Packaging1MG
- Price$408.4
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3946
- Product descriptionYK-4-279
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3946
- Product descriptionYK-4-279
- Packaging10mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3946
- Product descriptionYK-4-279
- Packaging50mg
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3946
- Product descriptionYK-4-279
- Packaging100mg
- Price$315
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2469
- Product descriptionYK4-279 99%
- Packaging10mg
- Price$104.5
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2469
- Product descriptionYK4-279 99%
- Packaging50mg
- Price$379.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13661
- Product descriptionYK-4-279 ≥98%
- Packaging1mg
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13661
- Product descriptionYK-4-279 ≥98%
- Packaging5mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13661
- Product descriptionYK-4-279 ≥98%
- Packaging10mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13661
- Product descriptionYK-4-279 ≥98%
- Packaging50mg
- Price$700
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | SYN5754 | YK-4-279 | 100mg | $567 | 2021-12-16 | Buy |
Alichem | 1037184443 | 4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one | 250mg | $714 | 2021-12-16 | Buy |
Alichem | 1037184443 | 4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one | 500mg | $960.4 | 2021-12-16 | Buy |
Alichem | 1037184443 | 4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one | 1g | $1853.5 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0008897 | 4,7-DICHLORO-1,3-DIHYDRO-3-HYDROXY-3-(2-(4-METHOXYPHENYL)-2-OXOETHYL)-2H-INDOLE-2-ONE 95.00% | 10MG | $484 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0008897 | 4,7-DICHLORO-1,3-DIHYDRO-3-HYDROXY-3-(2-(4-METHOXYPHENYL)-2-OXOETHYL)-2H-INDOLE-2-ONE 95.00% | 1MG | $408.4 | 2021-12-16 | Buy |
ApexBio Technology | A3946 | YK-4-279 | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
ApexBio Technology | A3946 | YK-4-279 | 10mg | $70 | 2021-12-16 | Buy |
ApexBio Technology | A3946 | YK-4-279 | 50mg | $210 | 2021-12-16 | Buy |
ApexBio Technology | A3946 | YK-4-279 | 100mg | $315 | 2021-12-16 | Buy |
Axon Medchem | Axon2469 | YK4-279 99% | 10mg | $104.5 | 2021-12-16 | Buy |
Axon Medchem | Axon2469 | YK4-279 99% | 50mg | $379.5 | 2021-12-16 | Buy |
Cayman Chemical | 13661 | YK-4-279 ≥98% | 1mg | $35 | 2021-12-16 | Buy |
Cayman Chemical | 13661 | YK-4-279 ≥98% | 5mg | $95 | 2021-12-16 | Buy |
Cayman Chemical | 13661 | YK-4-279 ≥98% | 10mg | $160 | 2021-12-16 | Buy |
Cayman Chemical | 13661 | YK-4-279 ≥98% | 50mg | $700 | 2021-12-16 | Buy |
Properties
Melting point :149-151℃
Boiling point :608.9±55.0 °C(Predicted)
Density :1.456
storage temp. :Store at -20° C.
solubility :insoluble in H2O; ≥16.35 mg/mL in DMSO; ≥24.25 mg/mL in EtOH with ultrasonic
form :Powder
pka :10.43±0.20(Predicted)
color :White to off-white
Boiling point :608.9±55.0 °C(Predicted)
Density :1.456
storage temp. :Store at -20° C.
solubility :insoluble in H2O; ≥16.35 mg/mL in DMSO; ≥24.25 mg/mL in EtOH with ultrasonic
form :Powder
pka :10.43±0.20(Predicted)
color :White to off-white
Safety Information
Symbol(GHS): |
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Description
ES-FLI1 is an oncogenic fusion protein found in Ewing’s sarcoma, a family of undifferentiated tumors that occur throughout the body. The binding of RNA helicase A (RHA) to ES-FLI1 promotes its oncogenic function. YK-4-279 is an inhibitor of protein-protein interactions between ES-FLI1 and RHA. At 10 μM, YK-4-279 blocks RHA binding to ES-FLI1 and induces apoptosis of a panel of Ewing’s sarcoma tumor cell lines with IC50 values ranging from 0.5-2 μM. At 1.5 mg per dose, YK-4-279 reduces the growth of Ewing’s sarcoma orthotopic xenografts in mice after treatment with the inhibitor for two weeks.More related product prices
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Suppliers and manufacturers
career henan chemical co
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Hubei xin bonus chemical co. LTD
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
ShenZhen Trendseen Biological Technology Co.,Ltd.
$1.00 /1KG
4,7-dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1H-indol-2-one CAS:1037184-44-3
4,7-dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1H-indol-2-one CAS:1037184-44-3