Teneligliptin
|
- $45 - $959.7
- Product name: Teneligliptin
- CAS: 760937-92-6
- MF: C22H30N6OS
- MW: 426.58
- EINECS:
- MDL Number:MFCD13195565
- Synonyms:teneligliptin;3-[[(2S,4S)-4-[4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl]-2-pyrrolidinyl]carbonyl]thiazolidine;Methanone,[(2S,4S)-4-[4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl]-2-pyrrolidinyl]-3-thiazolidinyl-;Teneligptin WS;[(2S,4S)-4-[4-(5-methyl-2-phenylpyrazol-3-yl)piperazin-1-yl]pyrrolidin-2-yl]-(1,3-thiazolidin-3-yl)methanone;API (Teneligliptin free base);Teliglietin;Teneligliptin (MP-513)
11 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 5MG
- 10mg
- 50mg
- 100MG
- 250mg
- 1g
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0014166
- Product descriptionTENELIGLIPTIN 95.00%
- Packaging5MG
- Price$502.54
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0014166
- Product descriptionTENELIGLIPTIN 95.00%
- Packaging100MG
- Price$959.7
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0882
- Product descriptionTeneligliptin 99.57%
- Packaging10mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0882
- Product descriptionTeneligliptin 99.57%
- Packaging50mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0882
- Product descriptionTeneligliptin 99.57%
- Packaging100mg
- Price$288
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0882
- Product descriptionTeneligliptin 99.57%
- Packaging250mg
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000853
- Product descriptionTeneligliptin 98+%
- Packaging50mg
- Price$126
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000853
- Product descriptionTeneligliptin 98+%
- Packaging100mg
- Price$196
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000853
- Product descriptionTeneligliptin 98+%
- Packaging250mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9428
- Product descriptionTeneligliptin >98%
- Packaging1g
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberT018295
- Product descriptionTeneligliptin
- Packaging10mg
- Price$45
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0014166 | TENELIGLIPTIN 95.00% | 5MG | $502.54 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0014166 | TENELIGLIPTIN 95.00% | 100MG | $959.7 | 2021-12-16 | Buy |
| ChemScene | CS-0882 | Teneligliptin 99.57% | 10mg | $60 | 2021-12-16 | Buy |
| ChemScene | CS-0882 | Teneligliptin 99.57% | 50mg | $180 | 2021-12-16 | Buy |
| ChemScene | CS-0882 | Teneligliptin 99.57% | 100mg | $288 | 2021-12-16 | Buy |
| ChemScene | CS-0882 | Teneligliptin 99.57% | 250mg | $600 | 2021-12-16 | Buy |
| Crysdot | CD31000853 | Teneligliptin 98+% | 50mg | $126 | 2021-12-16 | Buy |
| Crysdot | CD31000853 | Teneligliptin 98+% | 100mg | $196 | 2021-12-16 | Buy |
| Crysdot | CD31000853 | Teneligliptin 98+% | 250mg | $420 | 2021-12-16 | Buy |
| DC Chemicals | DC9428 | Teneligliptin >98% | 1g | $500 | 2021-12-16 | Buy |
| TRC | T018295 | Teneligliptin | 10mg | $45 | 2021-12-16 | Buy |
Properties
Melting point :>100°C (dec.)
Boiling point :663.4±55.0 °C(Predicted)
Density :1.38
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :8.70±0.10(Predicted)
color :Off-White
InChIKey :WGRQANOPCQRCME-PMACEKPBSA-N
SMILES :C([C@@H]1C[C@H](N2CCN(C3N(C4=CC=CC=C4)N=C(C)C=3)CC2)CN1)(N1CCSC1)=O
Boiling point :663.4±55.0 °C(Predicted)
Density :1.38
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :8.70±0.10(Predicted)
color :Off-White
InChIKey :WGRQANOPCQRCME-PMACEKPBSA-N
SMILES :C([C@@H]1C[C@H](N2CCN(C3N(C4=CC=CC=C4)N=C(C)C=3)CC2)CN1)(N1CCSC1)=O
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Teneligliptin was approved in September 2012 in Japan for the treatment of patients with Type 2 diabetes mellitus (T2DM). Teneligliptin is a member of the dipeptidyl peptidase 4 (DPP-4) inhibitor class of antidiabetes agents. DPP-4 is an enzyme that degrades GLP-1, a 30-amino acid peptide that is secreted in response to food intake. GLP-1 stimulates insulin secretion and inhibits glucagon secretion, which leads to lower levels of plasma glucose. Teneligliptin is one of a growing numbers of DPP-4 inhibitors to be approved worldwide. The discovery of teneligliptin was guided by structure-based design, with a key element being binding of the phenyl group in the S2 pocket, which not only increases potency for DPP-4, but also improves selectivity versus DPP-8 and DPP- 9. Teneligliptin is a potent inhibitor of DPP-4 in the enzyme inhibition assay (IC50=0.37 nM).Related product price
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