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ChemicalBook >> CAS DataBase List >> TAK-733

TAK-733

TAK-733 price.
  • $33 - $4171.86
  • Product name: TAK-733
  • CAS: 1035555-63-5
  • MF: C17H15F2IN4O4
  • MW: 504.23
  • EINECS:
  • MDL Number:MFCD24386349
  • Synonyms:TAK-733;TAK-733/TAK733;(R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione;(R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione TAK 733;(R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrim;CS-547;3-[(2r)-2,3-dihydroxypropyl]-6-fluoro-5-(2-fluoro-4-iodoanilino)-8-methylpyrido[2,3-d]pyrimidine-4,7-dione;Pyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione, 3-[(2R)-2,3-dihydroxypropyl]-6-fluoro-5-[(2-fluoro-4-iodophenyl)amino]-8-methyl-
24 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
Package
  • 500μg
  • 1mg
  • 2mg
  • 5MG
  • 10mg
  • 50mg
  • 100mg
  • 200MG
  • 250mg
  • 1g
  • 1000mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010228
  • Product descriptionTAK-733 95.00%
  • Packaging5MG
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010228
  • Product descriptionTAK-733 95.00%
  • Packaging200MG
  • Price$4171.86
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1621
  • Product descriptionTAK-733
  • Packaging50mg
  • Price$680
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0162
  • Product descriptionTAK-733
  • Packaging10mg
  • Price$298
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0162
  • Product descriptionTAK-733
  • Packaging5mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0162
  • Product descriptionTAK-733
  • Packaging2mg
  • Price$102
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60255
  • Product descriptionTAK-733
  • Packaging10mg
  • Price$378
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181157
  • Product descriptionTAK-733 >98%
  • Packaging1000mg
  • Price$3876
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181157
  • Product descriptionTAK-733 >98%
  • Packaging250mg
  • Price$1949.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT103481
  • Product descriptionTAK 733
  • Packaging10mg
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT103481
  • Product descriptionTAK 733
  • Packaging50mg
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16998
  • Product descriptionTAK-733 ≥98%
  • Packaging500μg
  • Price$33
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16998
  • Product descriptionTAK-733 ≥98%
  • Packaging1mg
  • Price$60
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16998
  • Product descriptionTAK-733 ≥98%
  • Packaging5mg
  • Price$208
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16998
  • Product descriptionTAK-733 ≥98%
  • Packaging10mg
  • Price$380
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1283
  • Product descriptionTAK-733 99.81%
  • Packaging5mg
  • Price$136
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0010228 TAK-733 95.00% 5MG $330 2021-12-16 Buy
American Custom Chemicals Corporation API0010228 TAK-733 95.00% 200MG $4171.86 2021-12-16 Buy
ApexBio Technology B1621 TAK-733 50mg $680 2021-12-16 Buy
Apolloscientific BISN0162 TAK-733 10mg $298 2021-12-16 Buy
Apolloscientific BISN0162 TAK-733 5mg $160 2021-12-16 Buy
Apolloscientific BISN0162 TAK-733 2mg $102 2021-12-16 Buy
Arctom CFN60255 TAK-733 10mg $378 2021-12-16 Buy
Biorbyt Ltd orb181157 TAK-733 >98% 1000mg $3876 2021-12-16 Buy
Biorbyt Ltd orb181157 TAK-733 >98% 250mg $1949.9 2021-12-16 Buy
Biosynth Carbosynth FT103481 TAK 733 10mg $225 2021-12-16 Buy
Biosynth Carbosynth FT103481 TAK 733 50mg $700 2021-12-16 Buy
Cayman Chemical 16998 TAK-733 ≥98% 500μg $33 2024-03-01 Buy
Cayman Chemical 16998 TAK-733 ≥98% 1mg $60 2024-03-01 Buy
Cayman Chemical 16998 TAK-733 ≥98% 5mg $208 2024-03-01 Buy
Cayman Chemical 16998 TAK-733 ≥98% 10mg $380 2024-03-01 Buy
ChemScene CS-1283 TAK-733 99.81% 5mg $136 2021-12-16 Buy

Properties

Boiling point :530.5±60.0 °C(Predicted)
Density :1.91±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥25.2 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :13.72±0.20(Predicted)
color :White to light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

TAK-733 is a potent and selective MEK allosteric site inhibitor for MEK1 with IC50 of 3.2 nM, inactive to Abl1, AKT3, c-RAF, CamK1, CDK2, c-Met, etc. Phase 1.

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