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ChemicalBook >> CAS DataBase List >> Shikalkin

Shikalkin

Shikalkin price.
  • $74.45 - $1620
  • Product name: Shikalkin
  • CAS: 54952-43-1
  • MF: C16H16O5
  • MW: 288.3
  • EINECS:
  • MDL Number:MFCD00016668
  • Synonyms:5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)naphthalene-1,4-dione;SHIKALKIN;1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)- (9ci);Arnebin-4;Nsc 291845;shiconin;Shikonin (mixture of optical isomers, about 1:1);1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-penten-1-yl)-
5 prices
Selected condition:
Brand
  • AK Scientific
  • Arctom
  • Sigma-Aldrich
  • TRC
Package
  • 5mg
  • 10mg
  • 50mg
  • ManufacturerAK Scientific
  • Product number0282AQ
  • Product descriptionShikonin
  • Packaging10mg
  • Price$162
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSY232843
  • Product description(±)-Shikonin ≥98%
  • Packaging10mg
  • Price$74.45
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberS7576
  • Product descriptionShikonin ≥98% (HPLC)
  • Packaging50mg
  • Price$1620
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberS7576
  • Product descriptionShikonin ≥98% (HPLC)
  • Packaging10mg
  • Price$473
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberS357605
  • Product description(±)-Shikonin
  • Packaging5mg
  • Price$85
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0282AQ Shikonin 10mg $162 2021-12-16 Buy
Arctom SY232843 (±)-Shikonin ≥98% 10mg $74.45 2021-12-16 Buy
Sigma-Aldrich S7576 Shikonin ≥98% (HPLC) 50mg $1620 2024-03-01 Buy
Sigma-Aldrich S7576 Shikonin ≥98% (HPLC) 10mg $473 2024-03-01 Buy
TRC S357605 (±)-Shikonin 5mg $85 2021-12-16 Buy

Properties

Melting point :144-145 °C
Boiling point :567.4±50.0 °C(Predicted)
Density :1.373±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :methanol: soluble1mg/mL
pka :7.34±0.20(Predicted)
form :powder or solid
color :red to brown
LogP :4.350 (est)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.

Description

Shikonin has been used:
  • to enhance the anti-tumor activity of gefitinib on tyrosine kinase receptor epidermal growth factor receptor (EGFR) in wild-type lung cancer cells
  • as an inhibitor of renal aerobic glycosis and a potential
  • as an anti-inflammatory agent to test its role to improve lipopolysaccharide (LPS)-induced cardiac dysfunction
  • to stimulate bone marrow-derived macrophages (BMDMs) to test the effect of Interferon regulatory factor 1 on cell death


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