Selexipag
- $45 - $5460
- Product name: Selexipag
- CAS: 475086-01-2
- MF: C26H32N4O4S
- MW: 496.62
- EINECS:
- MDL Number:MFCD10567093
- Synonyms:NS-304;ACT-293987;NS-304(Selexipag);Selexipag API;2-[4-[(5,6-diphenylpyrazin-2-yl)-propan-2-ylaMino]butoxy]-N-MethylsulfonylacetaMide;AcetaMide, 2-[4-[(5,6-diphenyl-2-pyrazinyl)(1-Methylethyl)aMino]butoxy]-N- (Methylsulfonyl)-;Selexipag intermediate 1;2-[4-[(5,6-Diphenylpyrazin-2-yl)(isopropyl)amino]butoxy]-N-(methylsulfonyl)acetamide
23 prices
Selected condition:
Brand
- AccelPharmtech
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Tocris
- TRC
Package
- 2mg
- 10mg
- 50
- 1mg
- 5mg
- 50mg
- 100mg
- 250mg
- 1g
- 5G
- 25G
- 10
- 100G
- ManufacturerAccelPharmtech
- Product numberXP1293
- Product descriptionSelexipag 98.00%
- Packaging100G
- Price$5460
- Updated2021-12-16
- Buy
- ManufacturerAccelPharmtech
- Product numberXP1293
- Product descriptionSelexipag 98.00%
- Packaging25G
- Price$1560
- Updated2021-12-16
- Buy
- ManufacturerAccelPharmtech
- Product numberXP1293
- Product descriptionSelexipag 98.00%
- Packaging5G
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7378
- Product descriptionNS304
- Packaging2mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD106425
- Product descriptionSelexipag
- Packaging10mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD106425
- Product descriptionSelexipag
- Packaging50mg
- Price$437.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10010411
- Product descriptionNS-304 ≥98%
- Packaging1mg
- Price$45
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010411
- Product descriptionNS-304 ≥98%
- Packaging5mg
- Price$198
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010411
- Product descriptionNS-304 ≥98%
- Packaging10mg
- Price$351
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010411
- Product descriptionNS-304 ≥98%
- Packaging50mg
- Price$1528
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM168173
- Product description2-(4-((5,6-diphenylpyrazin-2-yl)(isopropyl)amino)butoxy)-N-(methylsulfonyl)acetamide 95%+
- Packaging10mg
- Price$142
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM168173
- Product description2-(4-((5,6-diphenylpyrazin-2-yl)(isopropyl)amino)butoxy)-N-(methylsulfonyl)acetamide 95%+
- Packaging50mg
- Price$431
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3774
- Product descriptionSelexipag 99.89%
- Packaging5mg
- Price$114
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3774
- Product descriptionSelexipag 99.89%
- Packaging10mg
- Price$174
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3774
- Product descriptionSelexipag 99.89%
- Packaging50mg
- Price$576
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31001830
- Product descriptionNS-304 98+%
- Packaging50mg
- Price$497
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AccelPharmtech | XP1293 | Selexipag 98.00% | 100G | $5460 | 2021-12-16 | Buy |
AccelPharmtech | XP1293 | Selexipag 98.00% | 25G | $1560 | 2021-12-16 | Buy |
AccelPharmtech | XP1293 | Selexipag 98.00% | 5G | $420 | 2021-12-16 | Buy |
ApexBio Technology | B7378 | NS304 | 2mg | $110 | 2021-12-16 | Buy |
Biosynth Carbosynth | FD106425 | Selexipag | 10mg | $125 | 2021-12-16 | Buy |
Biosynth Carbosynth | FD106425 | Selexipag | 50mg | $437.5 | 2021-12-16 | Buy |
Cayman Chemical | 10010411 | NS-304 ≥98% | 1mg | $45 | 2024-03-01 | Buy |
Cayman Chemical | 10010411 | NS-304 ≥98% | 5mg | $198 | 2024-03-01 | Buy |
Cayman Chemical | 10010411 | NS-304 ≥98% | 10mg | $351 | 2024-03-01 | Buy |
Cayman Chemical | 10010411 | NS-304 ≥98% | 50mg | $1528 | 2024-03-01 | Buy |
Chemenu | CM168173 | 2-(4-((5,6-diphenylpyrazin-2-yl)(isopropyl)amino)butoxy)-N-(methylsulfonyl)acetamide 95%+ | 10mg | $142 | 2021-12-16 | Buy |
Chemenu | CM168173 | 2-(4-((5,6-diphenylpyrazin-2-yl)(isopropyl)amino)butoxy)-N-(methylsulfonyl)acetamide 95%+ | 50mg | $431 | 2021-12-16 | Buy |
ChemScene | CS-3774 | Selexipag 99.89% | 5mg | $114 | 2021-12-16 | Buy |
ChemScene | CS-3774 | Selexipag 99.89% | 10mg | $174 | 2021-12-16 | Buy |
ChemScene | CS-3774 | Selexipag 99.89% | 50mg | $576 | 2021-12-16 | Buy |
Crysdot | CD31001830 | NS-304 98+% | 50mg | $497 | 2021-12-16 | Buy |
Properties
Melting point :134-138°C
Density :1.210±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
pka :3.82±0.40(Predicted)
form :Solid
color :Pale Yellow
InChIKey :QXWZQTURMXZVHJ-UHFFFAOYSA-N
SMILES :C(NS(C)(=O)=O)(=O)COCCCCN(C1=NC(C2=CC=CC=C2)=C(C2=CC=CC=C2)N=C1)C(C)C
Density :1.210±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
pka :3.82±0.40(Predicted)
form :Solid
color :Pale Yellow
InChIKey :QXWZQTURMXZVHJ-UHFFFAOYSA-N
SMILES :C(NS(C)(=O)=O)(=O)COCCCCN(C1=NC(C2=CC=CC=C2)=C(C2=CC=CC=C2)N=C1)C(C)C
Safety Information
Symbol(GHS): | ||||||||||||||||||||||
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Signal word: | Warning | |||||||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
NS-304 is a potent vasorelaxant and inhibitor of human platelet aggregation that mediates its actions by binding to a specific G protein-coupled receptor, the IP receptor, on the surface of platelets and endothelial cells.The IP receptor also participates in signal transduction of the cardioprotection, inflammation and pain response. NS-304 is a prodrug of the active form of MRE-269, which is a potent and selective agonist for the human IP receptor with a Ki value of 20 nM. In contrast to PGI2, which has a half-life of 30 seconds to several minutes in vivo, NS-304 is long-acting. Plasma concentrations of MRE-269 remain near peak levels for more than eight hours in rats and dogs after NS-304 was administered orally.More related product prices
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