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ChemicalBook >> CAS DataBase List >> Salinomycin

Salinomycin

Salinomycin price.
  • $13 - $3465
  • Product name: Salinomycin
  • CAS: 55721-31-8
  • MF: C42H71NaO12
  • MW: 791
  • EINECS:611-309-0
  • MDL Number:MFCD00145265
  • Synonyms:SALINOMYCIN SODIUM SALT 2.5-HYDRATE;SALINOMYCIN SV SODIUM SALT 2,5-HYDRATE;Salinomycin hydrate monosodium salt;Salinomycin sodium premix;Salinomycin, monosodium salt;salinomycin monosodium salt hydrate;Salinomycin-Natrium;(2R)-2-[(5S,6R)-6-[(2S,3S,4S,6R)-6-[(2S,5R,7S,9S,10S,12R,15R)-2-[(2R,5R,6S)-5-Ethyl-5-hydroxy-6-methyloxan-2-yl]-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.5.3]pentadec-13-en-9-yl]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-5-methyloxan-2-yl]butanoic acid
13 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • ChemScene
  • Medical Isotopes, Inc.
  • TRC
Package
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 10G
  • 100G
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007727
  • Product descriptionSALINOMYCIN SODIUM SALT 90.00%
  • Packaging100G
  • Price$3465
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007727
  • Product descriptionSALINOMYCIN SODIUM SALT 90.00%
  • Packaging10G
  • Price$1183.88
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007727
  • Product descriptionSALINOMYCIN SODIUM SALT 90.00%
  • Packaging5MG
  • Price$126.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13579
  • Product descriptionSalinomycin (sodium salt) ≥90%
  • Packaging5mg
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13579
  • Product descriptionSalinomycin (sodium salt) ≥90%
  • Packaging10mg
  • Price$23
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13579
  • Product descriptionSalinomycin (sodium salt) ≥90%
  • Packaging50mg
  • Price$78
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13579
  • Product descriptionSalinomycin (sodium salt) ≥90%
  • Packaging100mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1493
  • Product descriptionSalinomycinsodiumsalt ≥98.0%
  • Packaging25mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1493
  • Product descriptionSalinomycinsodiumsalt ≥98.0%
  • Packaging50mg
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1493
  • Product descriptionSalinomycinsodiumsalt ≥98.0%
  • Packaging100mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number66985
  • Product descriptionSalinomycinSodiumSalt(12%min.)
  • Packaging100mg
  • Price$390
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberS088800
  • Product descriptionSalinomycinSodiumSalt(12%min.)
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberS088805
  • Product descriptionSalinomycinSodiumSalt
  • Packaging250mg
  • Price$870
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0007727 SALINOMYCIN SODIUM SALT 90.00% 100G $3465 2021-12-16 Buy
American Custom Chemicals Corporation API0007727 SALINOMYCIN SODIUM SALT 90.00% 10G $1183.88 2021-12-16 Buy
American Custom Chemicals Corporation API0007727 SALINOMYCIN SODIUM SALT 90.00% 5MG $126.5 2021-12-16 Buy
Cayman Chemical 13579 Salinomycin (sodium salt) ≥90% 5mg $13 2021-12-16 Buy
Cayman Chemical 13579 Salinomycin (sodium salt) ≥90% 10mg $23 2021-12-16 Buy
Cayman Chemical 13579 Salinomycin (sodium salt) ≥90% 50mg $78 2021-12-16 Buy
Cayman Chemical 13579 Salinomycin (sodium salt) ≥90% 100mg $130 2021-12-16 Buy
ChemScene CS-1493 Salinomycinsodiumsalt ≥98.0% 25mg $60 2021-12-16 Buy
ChemScene CS-1493 Salinomycinsodiumsalt ≥98.0% 50mg $84 2021-12-16 Buy
ChemScene CS-1493 Salinomycinsodiumsalt ≥98.0% 100mg $120 2021-12-16 Buy
Medical Isotopes, Inc. 66985 SalinomycinSodiumSalt(12%min.) 100mg $390 2021-12-16 Buy
TRC S088800 SalinomycinSodiumSalt(12%min.) 5mg $50 2021-12-16 Buy
TRC S088805 SalinomycinSodiumSalt 250mg $870 2021-12-16 Buy

Properties

Melting point :140-142°
alpha :D25 -37° (c = 1 in ethanol)
storage temp. :APPROX 4°C
solubility :Soluble in DMSO.
form :Solid
color :White
Merck :13,8415
BRN :4901827
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Cancer stems cells (CSCs) are a subpopulation of cells within tumors that drive tumor growth and recurrence. They are resistant to many current cancer treatments. Salinomycin (sodium salt) is an antibacterial and coccidiostat compound that shows selective toxicity for the CSCs that exist as a subpopulation within HMLER breast cancer cells (IC50s = ~24 versus ~90 μM). At 8 μM, salinomycin treatment of 4T1 and MCF-7-Ras breast cancer cell lines results in a ~2-fold and ~3-fold, respective reduction of CSCs relative to controls. Treatment of 5 mg/kg salinomycin in mice implanted with SUM159 human breast cancer cells inhibits mammary tumor growth and induces increased epithelial differentiation of tumor cells.

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