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ChemicalBook >> CAS DataBase List >> SC-51089

SC-51089

SC-51089 price.
  • $23 - $1686.3
  • Product name: SC-51089
  • CAS: 146033-02-5
  • MF: C22H19ClN4O3
  • MW: 422.86
  • EINECS:
  • MDL Number:MFCD00869867
  • Synonyms:SC-51089;8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic Acid 2-[1-Oxo-3-(4-pyridinyl)propyl]hydrazide Hydrochloride;8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid 2-[1-oxo-3-(4-pyridinyl)propyl]hydrazide monohydrochloride;8-Chlorodibenz(Z)[b,f][1,4]oxazepine-10(11H)-carboxylicacid2-[1-oxo-3-(4-pyridinyl)propyl]hydrazidehydrochloride;SC-51089 HCl;Dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-[1-oxo-3-(4-pyridinyl)propyl]hydrazide, hydrochloride (1:1)
14 prices
Selected condition：
Brand
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 50
  • 1mg
  • 5mg
  • 10MG
  • 25mg
  • 50mg
  • 10
  • 100MG
  • ManufacturerAK Scientific
  • Product number1508AH
  • Product description8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylicacid2-[1-oxo-3-(4-pyridinyl)propyl]hydrazidehydrochloride
  • Packaging1mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67130
  • Product descriptionSC-51089, 98%
  • Packaging5mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007807
  • Product descriptionSC-51089 95.00%
  • Packaging1MG
  • Price$141.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007807
  • Product descriptionSC-51089 95.00%
  • Packaging10MG
  • Price$716.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007807
  • Product descriptionSC-51089 95.00%
  • Packaging100MG
  • Price$1686.3
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7496
  • Product descriptionSC51089
  • Packaging50mg
  • Price$1190
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10011561
  • Product descriptionSC-51089 ≥95%
  • Packaging1mg
  • Price$23
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10011561
  • Product descriptionSC-51089 ≥95%
  • Packaging5mg
  • Price$63
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10011561
  • Product descriptionSC-51089 ≥95%
  • Packaging10mg
  • Price$113
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10011561
  • Product descriptionSC-51089 ≥95%
  • Packaging25mg
  • Price$253
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number3758
  • Product descriptionSC51089 ≥99%(HPLC)
  • Packaging10
  • Price$165
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number3758
  • Product descriptionSC51089 ≥99%(HPLC)
  • Packaging50
  • Price$694
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberS199860
  • Product descriptionSC-51089
  • Packaging50mg
  • Price$490
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number020859
  • Product descriptionSC-51089
  • Packaging10mg
  • Price$418
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1508AH 8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylicacid2-[1-oxo-3-(4-pyridinyl)propyl]hydrazidehydrochloride 1mg $120 2021-12-16 Buy
Alfa Aesar J67130 SC-51089, 98% 5mg $125 2021-12-16 Buy
American Custom Chemicals Corporation API0007807 SC-51089 95.00% 1MG $141.75 2021-12-16 Buy
American Custom Chemicals Corporation API0007807 SC-51089 95.00% 10MG $716.1 2021-12-16 Buy
American Custom Chemicals Corporation API0007807 SC-51089 95.00% 100MG $1686.3 2021-12-16 Buy
ApexBio Technology B7496 SC51089 50mg $1190 2021-12-16 Buy
Cayman Chemical 10011561 SC-51089 ≥95% 1mg $23 2024-03-01 Buy
Cayman Chemical 10011561 SC-51089 ≥95% 5mg $63 2024-03-01 Buy
Cayman Chemical 10011561 SC-51089 ≥95% 10mg $113 2024-03-01 Buy
Cayman Chemical 10011561 SC-51089 ≥95% 25mg $253 2024-03-01 Buy
Tocris 3758 SC51089 ≥99%(HPLC) 10 $165 2021-12-16 Buy
Tocris 3758 SC51089 ≥99%(HPLC) 50 $694 2021-12-16 Buy
TRC S199860 SC-51089 50mg $490 2021-12-16 Buy
Usbiological 020859 SC-51089 10mg $418 2021-12-16 Buy

Properties

Melting point :162-164°C
storage temp. :Store at -20°C
solubility :Soluble in DMSO (25 mg/ml) or water (25 mg/mL)
form :White solid.
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

SC-51089 is a selective antagonist of prostaglandin E2, which displays specificity towards the EP1 receptor subtype. Studies indicate that SC-51089 can induce nociceptive behaviors in rats as a result of its antagonistic effects on prostaglandin E2. This compound contains a diacylhydrazine moiety, which has often been observed to release hydrazine. Alternate studies suggest that SC-51089 can be metabolized by rat and human hepatocytes, however different metabolic products are produced. For instance, SC-51089 undergoes aromatic hydroxylation with consequent glucuronidation and sulphation in human hepatocytes, while oxidative N-dealkylation with opening of the oxazepine ring and consequent glucuronidation in observed in rat hepatocytes. SC-51089 is an inhibitor of EP2 and EP3.

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