PURVALANOL A
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- $22 - $1800
- Product name: PURVALANOL A
- CAS: 212844-53-6
- MF: C19H25ClN6O
- MW: 388.89
- EINECS:
- MDL Number:MFCD02179211
- Synonyms:PURVALANOL A;NG-60;6-(3-CHLOROANILINO)-2(1R)-ISOPROPYL-2-HYDROXYETHYLAMINO-9-ISOPROPYLPURINE;(2R)-2-[[6-[(3-CHLOROPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL;2-(1R-ISOPROPOYL-2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE;2-(1R-ISOPROPYL-2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYL-PURINE;CH61386;2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanolCDKinhibitor.
43 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
Package
- 1MG
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 10
- 250mg
- 500mg
- 50
- 1g
- 10mM(in 1mL DMSO)
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-2903-M005
- Product descriptionPurvalanol A ≥98%(HPLC)
- Packaging5mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3983AH
- Product descriptionPurvalanol A
- Packaging5mg
- Price$107
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA106338
- Product descriptionPurvalanol A 98+%
- Packaging2mg
- Price$22
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA106338
- Product descriptionPurvalanol A 98+%
- Packaging5mg
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA106338
- Product descriptionPurvalanol A 98+%
- Packaging10mg
- Price$38
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA106338
- Product descriptionPurvalanol A 98+%
- Packaging50mg
- Price$112
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA106338
- Product descriptionPurvalanol A 98+%
- Packaging100mg
- Price$212
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA106338
- Product descriptionPurvalanol A 98+%
- Packaging250mg
- Price$351
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA106338
- Product descriptionPurvalanol A 98+%
- Packaging1g
- Price$841
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000205
- Product descriptionPURVALANOL A 95.00%
- Packaging1MG
- Price$160.65
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000205
- Product descriptionPURVALANOL A 95.00%
- Packaging10MG
- Price$745.85
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000205
- Product descriptionPURVALANOL A 95.00%
- Packaging50MG
- Price$1417.71
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4990
- Product descriptionPurvalanol A
- Packaging5mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4990
- Product descriptionPurvalanol A
- Packaging10mM(in 1mL DMSO)
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4990
- Product descriptionPurvalanol A
- Packaging25mg
- Price$243
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4990
- Product descriptionPurvalanol A
- Packaging100mg
- Price$593
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-2903-M005 | Purvalanol A ≥98%(HPLC) | 5mg | $90 | 2021-12-16 | Buy |
| AK Scientific | 3983AH | Purvalanol A | 5mg | $107 | 2021-12-16 | Buy |
| Ambeed | A106338 | Purvalanol A 98+% | 2mg | $22 | 2021-12-16 | Buy |
| Ambeed | A106338 | Purvalanol A 98+% | 5mg | $28 | 2021-12-16 | Buy |
| Ambeed | A106338 | Purvalanol A 98+% | 10mg | $38 | 2021-12-16 | Buy |
| Ambeed | A106338 | Purvalanol A 98+% | 50mg | $112 | 2021-12-16 | Buy |
| Ambeed | A106338 | Purvalanol A 98+% | 100mg | $212 | 2021-12-16 | Buy |
| Ambeed | A106338 | Purvalanol A 98+% | 250mg | $351 | 2021-12-16 | Buy |
| Ambeed | A106338 | Purvalanol A 98+% | 1g | $841 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000205 | PURVALANOL A 95.00% | 1MG | $160.65 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000205 | PURVALANOL A 95.00% | 10MG | $745.85 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000205 | PURVALANOL A 95.00% | 50MG | $1417.71 | 2021-12-16 | Buy |
| ApexBio Technology | B4990 | Purvalanol A | 5mg | $68 | 2021-12-16 | Buy |
| ApexBio Technology | B4990 | Purvalanol A | 10mM(in 1mL DMSO) | $80 | 2021-12-16 | Buy |
| ApexBio Technology | B4990 | Purvalanol A | 25mg | $243 | 2021-12-16 | Buy |
| ApexBio Technology | B4990 | Purvalanol A | 100mg | $593 | 2021-12-16 | Buy |
Properties
Boiling point :590.5±60.0 °C(Predicted)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :methylene chloride: 50 mg/mL, clear, colorless
form :powder
pka :14.51±0.10(Predicted)
color :off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :methylene chloride: 50 mg/mL, clear, colorless
form :powder
pka :14.51±0.10(Predicted)
color :off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Purvalanol A is a potent, cell-permeable, and selective inhibitor of cyclin-dependent kinases (CDKs) with IC50 values of 4, 70, 35, 850, and 75 nM for cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk4/cyclin D1 and Cdk5-p35, respectively. Purvalanol A reversibly arrests synchronized cells in the G1 and G2 phase of the cell cycle, inhibiting both cell proliferation and cell death. At 10 μM, purvalanol A potently suppresses the anchorage-independent growth of c-Src-transformed cells as well as HT-29 and SW48 human colon cancer cells.More related product prices
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