PFK-015
|
- $44 - $2499
- Product name: PFK-015
- CAS: 4382-63-2
- MF: C17H12N2O
- MW: 260.29
- EINECS:
- MDL Number:MFCD28099813
- Synonyms:2-Propen-1-one, 1-(4-pyridinyl)-3-(2-quinolinyl)-;1-(4-Pyridinyl)-3-(2-quinolinyl)-2-propen-1-one PFK15;1-(Pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one;PFK-015;1-(4-Pyridinyl)-3-(2-quinolinyl)-2-propen-1-one;PFK015;PFK15;PFK 15;PFK-15;CS-1317;PFK15 (PFK-015)
18 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- Arctom
- Cayman Chemical
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberSYN5216
- Product descriptionPFK15
- Packaging100mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA131123
- Product description1-(Pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one 98+%
- Packaging5mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA131123
- Product description1-(Pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one 98+%
- Packaging10mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA131123
- Product description1-(Pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one 98+%
- Packaging50mg
- Price$227
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA131123
- Product description1-(Pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one 98+%
- Packaging100mg
- Price$294
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA131123
- Product description1-(Pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one 98+%
- Packaging1g
- Price$2499
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS445368
- Product description1-(Pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one ≥98%
- Packaging100mg
- Price$291
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17689
- Product descriptionPFK15 ≥95%
- Packaging5mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17689
- Product descriptionPFK15 ≥95%
- Packaging10mg
- Price$75
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17689
- Product descriptionPFK15 ≥95%
- Packaging25mg
- Price$165
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17689
- Product descriptionPFK15 ≥95%
- Packaging50mg
- Price$264
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD31001902
- Product descriptionPFK-015 98+%
- Packaging100mg
- Price$507
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31001902
- Product descriptionPFK-015 98+%
- Packaging50mg
- Price$278
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8026
- Product descriptionPFK-015 >98%
- Packaging100mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8026
- Product descriptionPFK-015 >98%
- Packaging250mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1009
- Product descriptionPFK15 ≥98% (HPLC)
- Packaging5mg
- Price$120
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5216 | PFK15 | 100mg | $650 | 2021-12-16 | Buy |
| Ambeed | A131123 | 1-(Pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one 98+% | 5mg | $104 | 2021-12-16 | Buy |
| Ambeed | A131123 | 1-(Pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one 98+% | 10mg | $135 | 2021-12-16 | Buy |
| Ambeed | A131123 | 1-(Pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one 98+% | 50mg | $227 | 2021-12-16 | Buy |
| Ambeed | A131123 | 1-(Pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one 98+% | 100mg | $294 | 2021-12-16 | Buy |
| Ambeed | A131123 | 1-(Pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one 98+% | 1g | $2499 | 2021-12-16 | Buy |
| Arctom | AS445368 | 1-(Pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one ≥98% | 100mg | $291 | 2021-12-16 | Buy |
| Cayman Chemical | 17689 | PFK15 ≥95% | 5mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 17689 | PFK15 ≥95% | 10mg | $75 | 2024-03-01 | Buy |
| Cayman Chemical | 17689 | PFK15 ≥95% | 25mg | $165 | 2024-03-01 | Buy |
| Cayman Chemical | 17689 | PFK15 ≥95% | 50mg | $264 | 2024-03-01 | Buy |
| Crysdot | CD31001902 | PFK-015 98+% | 100mg | $507 | 2021-12-16 | Buy |
| Crysdot | CD31001902 | PFK-015 98+% | 50mg | $278 | 2021-12-16 | Buy |
| DC Chemicals | DC8026 | PFK-015 >98% | 100mg | $250 | 2021-12-16 | Buy |
| DC Chemicals | DC8026 | PFK-015 >98% | 250mg | $450 | 2021-12-16 | Buy |
| Sigma-Aldrich | SML1009 | PFK15 ≥98% (HPLC) | 5mg | $120 | 2024-03-01 | Buy |
Properties
Boiling point :464.4±45.0 °C(Predicted)
Density :1.237±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :3.11±0.61(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Density :1.237±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :3.11±0.61(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Safety Information
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Description
6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) is a bifunctional enzyme that contains distinct domains for the phosphorylation of fructose 6-phosphate and the dephosphorylation of fructose 2,6-bisphosphate. PFKFB3 protein expression is elevated in most tumor types. PFK15 is a selective inhibitor of PFKFB3 (IC50 = 207 nM). It has no significant inhibitory effect on any member of a panel of 96 other kinases, and does not inhibit purified 6-phosphofructo-1-kinase, hexokinase, phosphoglucose isomerase, or PFKFB4. PFK15 rapidly induces apoptosis in transformed cells, suppresses glucose uptake and growth of Lewis lung carcinomas in syngeneic mice, and yields antitumor effects in human xenograft models of cancer in athymic mice.More related product prices
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