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ChemicalBook >> CAS DataBase List >> Otilonium bromide

Otilonium bromide

Otilonium bromide price.
  • $5 - $1805
  • Product name: Otilonium bromide
  • CAS: 26095-59-0
  • MF: C29H43BrN2O4
  • MW: 563.58
  • EINECS:247-457-4
  • MDL Number:MFCD00211142
  • Synonyms:Menoctyl;N,N-Diethyl-N-methy-2-[[4-[[2-(octyloxy)benzoyl]amino]benzoyl]oxy]ethanaminium Bromide;Pasminox;SP-63;Spasen;Spasmoctyl;Spasmome;OTYLONIUMBROMIDE
23 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Usbiological
Package
  • 10MG
  • 50mg
  • 10mM(in 1mL DMSO)
  • 5MG
  • 25MG
  • 0.1g
  • 100mg
  • 250mg
  • 5g
  • 25g
  • 100g
  • ManufacturerAHH
  • Product numberAPI-1697
  • Product descriptionOctyloniumbromide 98%
  • Packaging0.1g
  • Price$690
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberR504
  • Product descriptionOtiloniumbromide
  • Packaging5g
  • Price$81
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10938
  • Product descriptionOtiloniumbromide
  • Packaging100mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberR504
  • Product descriptionOtiloniumbromide
  • Packaging25g
  • Price$154
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberR504
  • Product descriptionOtiloniumbromide
  • Packaging100g
  • Price$374
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA237499
  • Product descriptionOtiloniumbromide 98+%
  • Packaging50mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA237499
  • Product descriptionOtiloniumbromide 98+%
  • Packaging5g
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA237499
  • Product descriptionOtiloniumbromide 98+%
  • Packaging25g
  • Price$76
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA237499
  • Product descriptionOtiloniumbromide 98+%
  • Packaging100g
  • Price$224
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0015873
  • Product descriptionOCTYLONIUM BROMIDE 95.00%
  • Packaging10MG
  • Price$224.7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0015873
  • Product descriptionOCTYLONIUM BROMIDE 95.00%
  • Packaging100MG
  • Price$1686.3
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1607
  • Product descriptionOtiloniumBromide
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29907
  • Product descriptionOtilonium (bromide)
  • Packaging10mg
  • Price$106
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29907
  • Product descriptionOtilonium (bromide)
  • Packaging50mg
  • Price$467
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29907
  • Product descriptionOtilonium (bromide)
  • Packaging100mg
  • Price$826
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29907
  • Product descriptionOtilonium (bromide)
  • Packaging250mg
  • Price$1805
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1697 Octyloniumbromide 98% 0.1g $690 2021-12-16 Buy
AK Scientific R504 Otiloniumbromide 5g $81 2021-12-16 Buy
AK Scientific J10938 Otiloniumbromide 100mg $95 2021-12-16 Buy
AK Scientific R504 Otiloniumbromide 25g $154 2021-12-16 Buy
AK Scientific R504 Otiloniumbromide 100g $374 2021-12-16 Buy
Ambeed A237499 Otiloniumbromide 98+% 50mg $5 2021-12-16 Buy
Ambeed A237499 Otiloniumbromide 98+% 5g $25 2021-12-16 Buy
Ambeed A237499 Otiloniumbromide 98+% 25g $76 2021-12-16 Buy
Ambeed A237499 Otiloniumbromide 98+% 100g $224 2021-12-16 Buy
American Custom Chemicals Corporation API0015873 OCTYLONIUM BROMIDE 95.00% 10MG $224.7 2021-12-16 Buy
American Custom Chemicals Corporation API0015873 OCTYLONIUM BROMIDE 95.00% 100MG $1686.3 2021-12-16 Buy
ApexBio Technology B1607 OtiloniumBromide 10mM(in 1mL DMSO) $60 2021-12-16 Buy
Cayman Chemical 29907 Otilonium (bromide) 10mg $106 2024-03-01 Buy
Cayman Chemical 29907 Otilonium (bromide) 50mg $467 2024-03-01 Buy
Cayman Chemical 29907 Otilonium (bromide) 100mg $826 2024-03-01 Buy
Cayman Chemical 29907 Otilonium (bromide) 250mg $1805 2024-03-01 Buy

Properties

Melting point :130-133°C
storage temp. :-20°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :powder
color :white to beige
CAS DataBase Reference :26095-59-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Otilonium is an inhibitor of L-type (IC50 = 2.3 μM) and T-type calcium channels (IC50s = 0.8, 1.1, and 0.4 μM for Cav3.1, Cav3.2, and Cav3.3, respectively). It is also an antagonist of muscarinic acetylcholine receptors (mAChRs; IC50s = 0.054, 0.4, 0.222, and 0.156 μM for M1, M2, M4, and M5 muscarinic receptors, respectively) and the platelet activating factor (PAF) receptor (IC50 = 0.0552 μM). Otilonium inhibits the inward calcium current in isolated rat colonic smooth muscle cells (EC50 = 885 nM), an effect that can be blocked by the L-type calcium channel inhibitor nifedipine . It inhibits contractions induced by the muscarinic acetylcholine receptor (mAChR) agonist methacholine in isolated circular muscle of the guinea pig proximal colon (IC50 = 3.7 μM). Otilonium (4 mg/kg) decreases fecal excretion and wet dog shakes and increases the tail withdrawal latency in the tail-flick test in a rat model of opioid withdrawal syndrome induced by morphine and naloxone.

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