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ChemicalBook >> CAS DataBase List >> Oridonin

Oridonin

Oridonin price.
  • $12 - $2567
  • Product name: Oridonin
  • CAS: 28957-04-2
  • MF: C20H28O6
  • MW: 364.44
  • EINECS:
  • MDL Number:MFCD00221762
  • Synonyms:Oridonin, R. rubescens;ISODONAL;(14r)-7-alpha,20-epoxy-1-alpha,6-beta,7,14-tetrahydroxykaur-16-en-15-one ;(1-alpha,6-beta,7-alpha,14r)-7,20-epoxy-1,6,7,14-tetrahydroxykaur-16-en-15-o ;,14r)- ;20-epoxy-1-alpha,6-beta,7,14-tetrahydroxy-7-alph(14r)-kaur-16-en-15-on ;kaur-16-en-15-one,7,20-epoxy-1,6,7,14-tetrahydroxy-,(1-alpha,6-beta,7-alpha ;Rubescensin
56 prices
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Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • JR MediChem
  • Labseeker
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 5mg
  • 10mg
  • 20mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500MG
  • 1g
  • 10g
  • 20g
  • 10mM(in 1mL DMSO)
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-O0131-M005
  • Product descriptionOridonin ≥98%(HPLC)
  • Packaging5mg
  • Price$41
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ53498
  • Product descriptionOridonin
  • Packaging25mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA472649
  • Product descriptionOridonin 99+%
  • Packaging10mg
  • Price$12
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA472649
  • Product descriptionOridonin 99+%
  • Packaging50mg
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA472649
  • Product descriptionOridonin 99+%
  • Packaging100mg
  • Price$43
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA472649
  • Product descriptionOridonin 99+%
  • Packaging250mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA472649
  • Product descriptionOridonin 99+%
  • Packaging1g
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBIO0000210
  • Product descriptionORIDONIN 95.00%
  • Packaging25MG
  • Price$619.47
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBIO0000210
  • Product descriptionORIDONIN 95.00%
  • Packaging100MG
  • Price$766.7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBIO0000210
  • Product descriptionORIDONIN 95.00%
  • Packaging500MG
  • Price$1282.12
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1802
  • Product descriptionOridonin
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1802
  • Product descriptionOridonin
  • Packaging20mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS569107
  • Product descriptionOridonin ≥99%
  • Packaging10mg
  • Price$34
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN99164
  • Product descriptionOridonin
  • Packaging20mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS569107
  • Product descriptionOridonin ≥99%
  • Packaging50mg
  • Price$58
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSY074724
  • Product descriptionOridonin
  • Packaging10mg
  • Price$65.45
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-O0131-M005 Oridonin ≥98%(HPLC) 5mg $41 2021-12-16 Buy
AK Scientific J53498 Oridonin 25mg $70 2021-12-16 Buy
Ambeed A472649 Oridonin 99+% 10mg $12 2021-12-16 Buy
Ambeed A472649 Oridonin 99+% 50mg $29 2021-12-16 Buy
Ambeed A472649 Oridonin 99+% 100mg $43 2021-12-16 Buy
Ambeed A472649 Oridonin 99+% 250mg $75 2021-12-16 Buy
Ambeed A472649 Oridonin 99+% 1g $180 2021-12-16 Buy
American Custom Chemicals Corporation BIO0000210 ORIDONIN 95.00% 25MG $619.47 2021-12-16 Buy
American Custom Chemicals Corporation BIO0000210 ORIDONIN 95.00% 100MG $766.7 2021-12-16 Buy
American Custom Chemicals Corporation BIO0000210 ORIDONIN 95.00% 500MG $1282.12 2021-12-16 Buy
ApexBio Technology N1802 Oridonin 10mM(in 1mL DMSO) $60 2021-12-16 Buy
ApexBio Technology N1802 Oridonin 20mg $70 2021-12-16 Buy
Arctom AS569107 Oridonin ≥99% 10mg $34 2021-12-16 Buy
Arctom CFN99164 Oridonin 20mg $40 2021-12-16 Buy
Arctom AS569107 Oridonin ≥99% 50mg $58 2021-12-16 Buy
Arctom SY074724 Oridonin 10mg $65.45 2021-12-16 Buy

Properties

Melting point :248-250°C
Boiling point :599.8±50.0 °C(Predicted)
Density :1.42±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: >20mg/mL
form :Yellow solid
pka :10.96±0.70(Predicted)
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
InChIKey :SDHTXBWLVGWJFT-WNKSEERENA-N
SMILES :O[C@@]12OC[C@]3([C@H](CCC(C)(C)[C@@]3([H])[C@@H]1O)O)[C@]1([H])CC[C@@]3([H])C(=C)C(=O)[C@@]21C3([H])O |&1:1,4,5,11,13,16,20,26,r|

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

A cell-permeable diterpenoid compound that possesses anti NF-κB activity and displays antiproliferative (ED50 ~ 2.7 g/ml in lymphoid malignant cells) and antiangiogenic properties (significantly inhibits network formation of HMEC-1 cells at 2.5 g/ml). Reported to affect DNA synthesis, induce apoptosis and initiate cell cycle arrest. Shown to efficiently block both TNF-α and LPS-induced NF-κB activity in Jurkat and in RAW264.7 murine macrophages, and inhibit p65 NF-κB transcriptional activity (IC50 ~ 5 g/ml in MT-1 cells) by disrupting NF-κB DNA-binding activity without interfering with its nuclear translocation.

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