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ChemicalBook >> CAS DataBase List >> Mitomycin C

Mitomycin C

Mitomycin C price.
  • $39 - $3990
  • Product name: Mitomycin C
  • CAS: 50-07-7
  • MF: C15H18N4O5
  • MW: 334.33
  • EINECS:200-008-6
  • MDL Number:MFCD00078109
  • Synonyms:Mitomycin C(Ametycine);Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-;Mytomycin C;[1aR-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-α]indole-4,7-dione;6-Amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methox-5-methylazirino[2',3':3,4]pyrrolo[1,2-;MitonyycinC;[1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione;8balpha)]-8aalph
44 prices
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  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • Alfa Aesar
  • ApexBio Technology
  • Apolloscientific
  • AvaChem
  • Biosynth Carbosynth
  • BroadPharm
  • Cayman Chemical
  • Chem-Impex
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  • 10mM(in 1mL DMSO)
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  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-M0161-M005
  • Product descriptionMitomycin C
  • Packaging5mg
  • Price$47
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-M0161-M010
  • Product descriptionMitomycin C
  • Packaging10mg
  • Price$82
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberMT-54310
  • Product descriptionMitomycin 98%
  • Packaging0.1g
  • Price$310
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberC474
  • Product descriptionMitomycin C
  • Packaging5mg
  • Price$49
  • Updated2021-12-16
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  • ManufacturerAlfa Aesar
  • Product numberJ63193
  • Product descriptionMitomycin C
  • Packaging10mg
  • Price$182
  • Updated2023-06-20
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  • ManufacturerAlfa Aesar
  • Product numberJ67460
  • Product descriptionMitomycin C, 5 mg/ml in DMSO, sterile-filtered
  • Packaging1ml
  • Price$401
  • Updated2023-06-20
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  • ManufacturerApexBio Technology
  • Product numberA4452
  • Product descriptionMitomycin C
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4452
  • Product descriptionMitomycin C
  • Packaging10mM(in 1mL DMSO)
  • Price$58
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA4452
  • Product descriptionMitomycin C
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIM0133
  • Product descriptionMitomycin C
  • Packaging5mg
  • Price$66
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIM0133
  • Product descriptionMitomycin C
  • Packaging10mg
  • Price$122
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIM0133
  • Product descriptionMitomycin C
  • Packaging25mg
  • Price$232
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number1996
  • Product descriptionMitomycin C
  • Packaging5mg
  • Price$39
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number1996
  • Product descriptionMitomycin C
  • Packaging10mg
  • Price$49
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1996
  • Product descriptionMitomycin C
  • Packaging25mg
  • Price$79
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1996
  • Product descriptionMitomycin C
  • Packaging100mg
  • Price$229
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-M0161-M005 Mitomycin C 5mg $47 2021-12-16 Buy
Adipogen Life Sciences CDX-M0161-M010 Mitomycin C 10mg $82 2021-12-16 Buy
AHH MT-54310 Mitomycin 98% 0.1g $310 2021-12-16 Buy
AK Scientific C474 Mitomycin C 5mg $49 2021-12-16 Buy
Alfa Aesar J63193 Mitomycin C 10mg $182 2023-06-20 Buy
Alfa Aesar J67460 Mitomycin C, 5 mg/ml in DMSO, sterile-filtered 1ml $401 2023-06-20 Buy
ApexBio Technology A4452 Mitomycin C 5mg $50 2021-12-16 Buy
ApexBio Technology A4452 Mitomycin C 10mM(in 1mL DMSO) $58 2021-12-16 Buy
ApexBio Technology A4452 Mitomycin C 10mg $70 2021-12-16 Buy
Apolloscientific BIM0133 Mitomycin C 5mg $66 2021-12-16 Buy
Apolloscientific BIM0133 Mitomycin C 10mg $122 2021-12-16 Buy
Apolloscientific BIM0133 Mitomycin C 25mg $232 2021-12-16 Buy
AvaChem 1996 Mitomycin C 5mg $39 2021-12-16 Buy
AvaChem 1996 Mitomycin C 10mg $49 2021-12-16 Buy
AvaChem 1996 Mitomycin C 25mg $79 2021-12-16 Buy
AvaChem 1996 Mitomycin C 100mg $229 2021-12-16 Buy

Properties

Melting point :360 °C
Boiling point :471.14°C (rough estimate)
Density :1.2238 (rough estimate)
refractive index :1.6800 (estimate)
storage temp. :2-8°C
solubility :H2O: 4 mL/vial Stock solutions should be filter sterilized and stored at 2-8 °C in the dark., clear to slightly hazy, blue to purple
form :powder
pka :pKa 2.8(H2O,t =25,I=0.1) (Uncertain)
color :blue-gray
PH :pH (0.5 g/l, 25℃ : )5.0～7.0
Water Solubility :soluble
Merck :14,6215
BRN :7231816
Stability :Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.
CAS DataBase Reference :50-07-7(CAS DataBase Reference)
IARC :2B (Vol. 10, Sup 7) 1987
EPA Substance Registry System :Mitomycin C (50-07-7)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Mitomycin C (MMC), an antineoplastic antibiotic derived from Streptomyces caespitosus or Streptomyces lavendulae, is a cell cycle-specific alkylating agent, inhibits DNA synthesis through covalent mitomycin C-DNA adduct with EC50 values of 0.14μM in PC3 cells. Therefore, it was served as a chemotherapeutic agent that has demonstrated its antitumor activity and has been used widely in treatment of various cancers.
Although it is active against a wide variety of tumors, newer agents have largely replaced MMC except in anal cancer; outside of the United States, MMC is infrequently used for treatment of advanced non-small cell lung cancer (NSCLC), and breast cancer.

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