MK8745
- $49 - $1200
- Product name: MK8745
- CAS: 885325-71-3
- MF: C20H19ClFN5OS
- MW: 431.91
- EINECS:
- MDL Number:MFCD28009367
- Synonyms:MK8745;6-[[4-(3-Chloro-2-fluorobenzoyl)piperazin-1-yl]methyl]-N-(thiazol-2-yl)pyridin-2-amine;Methanone, (3-chloro-2-fluorophenyl)[4-[[6-(2-thiazolylamino)-2-pyridinyl]methyl]-1-piperazinyl]-;(3-chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone. MK-8745;(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanon;CS-1904;MK8745 USP/EP/BP;Inhibitor,inhibit,MK8745,Aurora Kinase,MK-8745,MK 8745,Apoptosis
21 prices
Selected condition:
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- TRC
Package
- 10mM(in 1mL DMSO)
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number2550AH
- Product description(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone
- Packaging5mg
- Price$152
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2550AH
- Product description(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone
- Packaging10mg
- Price$194
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2550AH
- Product description(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone
- Packaging25mg
- Price$310
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2550AH
- Product description(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone
- Packaging50mg
- Price$415
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8807
- Product descriptionMK-8745
- Packaging10mM(in 1mL DMSO)
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8807
- Product descriptionMK-8745
- Packaging10mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8807
- Product descriptionMK-8745
- Packaging50mg
- Price$189
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number26190
- Product descriptionMK-8745
- Packaging5mg
- Price$49
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number26190
- Product descriptionMK-8745
- Packaging10mg
- Price$87
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number26190
- Product descriptionMK-8745
- Packaging25mg
- Price$190
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number26190
- Product descriptionMK-8745
- Packaging50mg
- Price$286
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM170040
- Product description(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone 98%
- Packaging100mg
- Price$230
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5664
- Product descriptionMK-8745 99.28%
- Packaging10mg
- Price$72
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5664
- Product descriptionMK-8745 99.28%
- Packaging50mg
- Price$216
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5664
- Product descriptionMK-8745 99.28%
- Packaging100mg
- Price$396
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31000418
- Product descriptionMK-8745 98+%
- Packaging10mg
- Price$50
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 2550AH | (3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone | 5mg | $152 | 2021-12-16 | Buy |
AK Scientific | 2550AH | (3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone | 10mg | $194 | 2021-12-16 | Buy |
AK Scientific | 2550AH | (3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone | 25mg | $310 | 2021-12-16 | Buy |
AK Scientific | 2550AH | (3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone | 50mg | $415 | 2021-12-16 | Buy |
ApexBio Technology | A8807 | MK-8745 | 10mM(in 1mL DMSO) | $60 | 2021-12-16 | Buy |
ApexBio Technology | A8807 | MK-8745 | 10mg | $68 | 2021-12-16 | Buy |
ApexBio Technology | A8807 | MK-8745 | 50mg | $189 | 2021-12-16 | Buy |
Cayman Chemical | 26190 | MK-8745 | 5mg | $49 | 2024-03-01 | Buy |
Cayman Chemical | 26190 | MK-8745 | 10mg | $87 | 2024-03-01 | Buy |
Cayman Chemical | 26190 | MK-8745 | 25mg | $190 | 2024-03-01 | Buy |
Cayman Chemical | 26190 | MK-8745 | 50mg | $286 | 2024-03-01 | Buy |
Chemenu | CM170040 | (3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone 98% | 100mg | $230 | 2021-12-16 | Buy |
ChemScene | CS-5664 | MK-8745 99.28% | 10mg | $72 | 2021-12-16 | Buy |
ChemScene | CS-5664 | MK-8745 99.28% | 50mg | $216 | 2021-12-16 | Buy |
ChemScene | CS-5664 | MK-8745 99.28% | 100mg | $396 | 2021-12-16 | Buy |
Crysdot | CD31000418 | MK-8745 98+% | 10mg | $50 | 2021-12-16 | Buy |
Properties
Melting point :177-179°C
Boiling point :605.5±65.0 °C(Predicted)
Density :1.430±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
form :Solid
pka :5.20±0.10(Predicted)
color :Off-White
Boiling point :605.5±65.0 °C(Predicted)
Density :1.430±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
form :Solid
pka :5.20±0.10(Predicted)
color :Off-White
Safety Information
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Signal word: | Warning | |||||||||||||||||||||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
MK-8745 is a potent and selective Aurora A kinase inhibitor that induces apoptotic cell death in a p53-dependent manner when tested in vitro in cell lines of multiple lineages.Related product price
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