Losartan Carboxaldehyde
|
- $57 - $1493.5
- Product name: Losartan Carboxaldehyde
- CAS: 114798-36-6
- MF: C22H21ClN6O
- MW: 420.89
- EINECS:
- MDL Number:MFCD00870256
- Synonyms:2-Butyl-4-chloro-1-[[2(1H-tetrazol-5-yl)[1,1biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxaldehyde;DUP 167;EXP 3179;Losartan Carboxaldehyde Discontinued see product # L470505;Losartan Carboxaldehyde;2-(Butyl-d3)-4-chloro-1-[[2(1H-tetrazol-5-yl)[1,1biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxaldehyde;Losartan Carboxaldehyde-d3;Losartan EP IMpurity K (LosaratnCarboxaldehyde)
14 prices
Selected condition：
Brand
- AK Scientific
- Alichem
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Crysdot
- TRC
- Usbiological
Package
- 1mg
- 2mg
- 5MG
- 10mg
- 50mg
- 250mg
- ManufacturerAK Scientific
- Product number3108CR
- Product descriptionLosartanCarboxaldehyde
- Packaging1mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number114798366
- Product description1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazole-5-carbaldehyde
- Packaging250mg
- Price$1493.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberRME0000173
- Product descriptionLOSARTAN CARBOXALDEHYDE-D3 95.00%
- Packaging5MG
- Price$496.44
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3539
- Product descriptionLosartanCarboxaldehyde
- Packaging1mg
- Price$62
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3539
- Product descriptionLosartanCarboxaldehyde
- Packaging5mg
- Price$172
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3539
- Product descriptionLosartanCarboxaldehyde
- Packaging10mg
- Price$281
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18855
- Product descriptionLosartan Carboxaldehyde ≥95%
- Packaging1mg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18855
- Product descriptionLosartan Carboxaldehyde ≥95%
- Packaging5mg
- Price$152
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18855
- Product descriptionLosartan Carboxaldehyde ≥95%
- Packaging10mg
- Price$249
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD11346592
- Product description1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazole-5-carbaldehyde 97%
- Packaging250mg
- Price$1450
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberL470505
- Product descriptionLosartanCarboxaldehyde
- Packaging50mg
- Price$670
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number281287
- Product descriptionLosartan carboxaldehyde
- Packaging2mg
- Price$345
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number015678
- Product descriptionLosartan Carboxaldehyde
- Packaging10mg
- Price$403
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number015679
- Product descriptionLosartan Carboxaldehyde-d3
- Packaging1mg
- Price$403
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3108CR | LosartanCarboxaldehyde | 1mg | $160 | 2021-12-16 | Buy |
| Alichem | 114798366 | 1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazole-5-carbaldehyde | 250mg | $1493.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | RME0000173 | LOSARTAN CARBOXALDEHYDE-D3 95.00% | 5MG | $496.44 | 2021-12-16 | Buy |
| ApexBio Technology | C3539 | LosartanCarboxaldehyde | 1mg | $62 | 2021-12-16 | Buy |
| ApexBio Technology | C3539 | LosartanCarboxaldehyde | 5mg | $172 | 2021-12-16 | Buy |
| ApexBio Technology | C3539 | LosartanCarboxaldehyde | 10mg | $281 | 2021-12-16 | Buy |
| Cayman Chemical | 18855 | Losartan Carboxaldehyde ≥95% | 1mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 18855 | Losartan Carboxaldehyde ≥95% | 5mg | $152 | 2024-03-01 | Buy |
| Cayman Chemical | 18855 | Losartan Carboxaldehyde ≥95% | 10mg | $249 | 2024-03-01 | Buy |
| Crysdot | CD11346592 | 1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazole-5-carbaldehyde 97% | 250mg | $1450 | 2021-12-16 | Buy |
| TRC | L470505 | LosartanCarboxaldehyde | 50mg | $670 | 2021-12-16 | Buy |
| Usbiological | 281287 | Losartan carboxaldehyde | 2mg | $345 | 2021-12-16 | Buy |
| Usbiological | 015678 | Losartan Carboxaldehyde | 10mg | $403 | 2021-12-16 | Buy |
| Usbiological | 015679 | Losartan Carboxaldehyde-d3 | 1mg | $403 | 2021-12-16 | Buy |
Properties
Melting point :84-86°C
Boiling point :666.7±65.0 °C(Predicted)
Density :1.34±0.1 g/cm3(Predicted)
storage temp. :Refrigerator, Under Inert Atmosphere
solubility :Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form :Solid
pka :4.16±0.10(Predicted)
color :Off-White to Light Yellow
CAS DataBase Reference :114798-36-6
Boiling point :666.7±65.0 °C(Predicted)
Density :1.34±0.1 g/cm3(Predicted)
storage temp. :Refrigerator, Under Inert Atmosphere
solubility :Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form :Solid
pka :4.16±0.10(Predicted)
color :Off-White to Light Yellow
CAS DataBase Reference :114798-36-6
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
Losartan carboxaldehyde is an intermediate aldehyde metabolite of the angiotensin II type 1 receptor antagonist, losartan . It does not block angiotensin receptors, but instead inhibits endothelial cyclooxygenase (COX)-2 expression, thereby exerting anti-inflammatory actions. At 1 μM in vitro, losartan carboxaldehyde has also been shown to block the upregulation of intercellular adhesion molecule (ICAM)-1 mRNA and COX-dependent generation of thromboxane A2 and prostaglandin F2α . Losartan carboxaldehyde can also act as a partial agonist (EC50 = 17.1 μM) of the insulin-sensitizing peroxisome proliferator-activated receptor γ in vitro.Related product price
- 124750-92-1
$7-1750 - Losartan
$6-1500 - Losartan potassium
$5-541
