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ChemicalBook >> CAS DataBase List >> LY 456236

LY 456236

LY 456236 price.
  • $125 - $896
  • Product name: LY 456236
  • CAS: 338736-46-2
  • MF: C16H16ClN3O2
  • MW: 317.77
  • EINECS:
  • MDL Number:MFCD08703117
  • Synonyms:(4-Methoxy-phenyl)-(6-methoxy-quinazolin-4-yl)-amine hydrochloride;LY456236 HCl
5 prices
Selected condition:
Brand
  • ApexBio Technology
  • Crysdot
  • Medical Isotopes, Inc.
  • TRC
Package
  • 10mg
  • 25mg
  • 50mg
  • ManufacturerApexBio Technology
  • Product numberB7037
  • Product descriptionLY456236hydrochloride
  • Packaging10mg
  • Price$219
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7037
  • Product descriptionLY456236hydrochloride
  • Packaging50mg
  • Price$896
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD00004640
  • Product descriptionLY456236Hydrochloride 97%
  • Packaging10mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number41217
  • Product descriptionLY456236
  • Packaging10mg
  • Price$610
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberL486730
  • Product descriptionLY456236
  • Packaging25mg
  • Price$125
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology B7037 LY456236hydrochloride 10mg $219 2021-12-16 Buy
ApexBio Technology B7037 LY456236hydrochloride 50mg $896 2021-12-16 Buy
Crysdot CD00004640 LY456236Hydrochloride 97% 10mg $220 2021-12-16 Buy
Medical Isotopes, Inc. 41217 LY456236 10mg $610 2021-12-16 Buy
TRC L486730 LY456236 25mg $125 2021-12-16 Buy

Properties

storage temp. :2-8°C
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

LY 456236 hydrochloride is a selective mGluR-1a (mGluR-1) antagonist (IC50 values are 143 nM and > 10 μM for mGluR-1 and mGluR-5 respectively). mGluR (Metabotropic glutamate receptors) are divided group I, group II, and group III. Group I receptors are coupled to Gq/11and are activators of phospholipase C.

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