LY 2606368
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- $116 - $4175
- Product name: LY 2606368
- CAS: 1234015-52-1
- MF: C18H19N7O2
- MW: 365.39
- EINECS:
- MDL Number:MFCD25977016
- Synonyms:LY 2606368;5-((5-(2-(3-aminopropoxy)-6-methoxyphenyl)-1H-pyrazol-3-yl)amino)pyrazine-2-carbonitrile LY2606368;5-[[5-[2-(3-Aminopropoxy)-6-methoxyphenyl]-1H-pyrazol-3-yl]amino]-2-pyrazinecarbonitrile;5-((5-(2-(3-aminopropoxy)-6-methoxyphenyl)-1H-pyrazol-3-yl)amino)pyrazine-2-carbonitrile;Prexasertib;LY 2606368;LY-2606368;PREXASERTIB;Prexasertib (LY2606368);CS-1453
30 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- TRC
- Usbiological
Package
- 0.5mg
- 500ug
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number5000DG
- Product descriptionPrexasertib
- Packaging1mg
- Price$226
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number5000DG
- Product descriptionPrexasertib
- Packaging5mg
- Price$640
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB8313
- Product descriptionLY2606368HCl
- Packaging5mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1088
- Product descriptionLY2606368
- Packaging5mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB8313
- Product descriptionLY2606368HCl
- Packaging25mg
- Price$660
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1088
- Product descriptionLY2606368
- Packaging25mg
- Price$660
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA161375
- Product descriptionLY2606368
- Packaging1mg
- Price$145
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA161375
- Product descriptionLY2606368
- Packaging2mg
- Price$232
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA161375
- Product descriptionLY2606368
- Packaging5mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA161375
- Product descriptionLY2606368
- Packaging10mg
- Price$610
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA161375
- Product descriptionLY2606368
- Packaging25mg
- Price$1250
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21490
- Product descriptionLY2606368 ≥98%
- Packaging1mg
- Price$116
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21490
- Product descriptionLY2606368 ≥98%
- Packaging5mg
- Price$486
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21490
- Product descriptionLY2606368 ≥98%
- Packaging10mg
- Price$799
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21490
- Product descriptionLY2606368 ≥98%
- Packaging25mg
- Price$1141
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-2198
- Product descriptionPrexasertib 98.22%
- Packaging5mg
- Price$160
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 5000DG | Prexasertib | 1mg | $226 | 2021-12-16 | Buy |
| AK Scientific | 5000DG | Prexasertib | 5mg | $640 | 2021-12-16 | Buy |
| ApexBio Technology | B8313 | LY2606368HCl | 5mg | $220 | 2021-12-16 | Buy |
| ApexBio Technology | B1088 | LY2606368 | 5mg | $220 | 2021-12-16 | Buy |
| ApexBio Technology | B8313 | LY2606368HCl | 25mg | $660 | 2021-12-16 | Buy |
| ApexBio Technology | B1088 | LY2606368 | 25mg | $660 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA161375 | LY2606368 | 1mg | $145 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA161375 | LY2606368 | 2mg | $232 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA161375 | LY2606368 | 5mg | $420 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA161375 | LY2606368 | 10mg | $610 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA161375 | LY2606368 | 25mg | $1250 | 2021-12-16 | Buy |
| Cayman Chemical | 21490 | LY2606368 ≥98% | 1mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 21490 | LY2606368 ≥98% | 5mg | $486 | 2024-03-01 | Buy |
| Cayman Chemical | 21490 | LY2606368 ≥98% | 10mg | $799 | 2024-03-01 | Buy |
| Cayman Chemical | 21490 | LY2606368 ≥98% | 25mg | $1141 | 2024-03-01 | Buy |
| ChemScene | CS-2198 | Prexasertib 98.22% | 5mg | $160 | 2021-12-16 | Buy |
Properties
Boiling point :608.5±55.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in DMSO
form :A crystalline solid
pka :11.89±0.10(Predicted)
color :Light yellow to brown
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in DMSO
form :A crystalline solid
pka :11.89±0.10(Predicted)
color :Light yellow to brown
Safety Information
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Description
LY2606368 is a checkpoint kinase 1 (Chk1) inhibitor with a Ki value of 0.9 nM against the purified target and IC50 values of <13 nM in a viability study of multiple colorectal cancer cell lines. Inhibition of Chk1 causes double-strand DNA breakage in cells leading to an excessive cell damage burden and subsequent cell death. In vitro, LY2606368 inhibits the doxorubicin-activated G2/M checkpoint in p53-deficient HeLa cells with an EC50 value of 9 nM. LY2606368, at 25 nM, also significantly induces apoptosis and inhibits colony formation in AGS and MKN1 gastric cancer cells.More related product prices
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