Glimepiride
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- $29 - $1750
- Product name: Glimepiride
- CAS: 93479-97-1
- MF: C24H34N4O5S
- MW: 490.62
- EINECS:642-919-5
- MDL Number:MFCD00878417
- Synonyms:3-ETHYL-2,5-DIHYDRO-4-METHYL-N-[2-[4-[[[[(TRANS-4-METHYLCYCLOHEXYL)AMINO]CARBONYL]AMINO]SULFONYL]PHENYL]ETHYL]-2-OXO-1H-PYRROLE-1-CARBOXAMIDE;3-ETHYL-2,5-DIHYDRO-4-METHYL-N-[2-[4-[[[[(TRANS-4-METHYLCYCLOHEXYL)AMINO]CARBONYL]AMINO]SULFONYL]PHENYL]ETHYL]-2-OXO-1H-PYRROLE-1-CARBOXYAMIDE;Gliclazide(diamicron);CLIMEPIRIDE;trans-3-Ethyl-2，5-dihydro-4-methyl-N-[2-[4-[[[[(4-methyleyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide;3-Ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[trans-4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxyamide;1H-Pyrrole-1-carboxamide, 3-ethyl-2,5-dihydro-4-methyl-N-2-4-(trans-4-methylcyclohexyl)aminocarbonylaminosulfonylphenylethyl-2-oxo-;1H-Pyrrole-1-carboxamide, 2,5-dihydro-3-ethyl-4-methyl-N-(2-(4-(((((4-methylcyclohexyl)amino) carbonyl)amino)sulfonyl)phenyl)ethyl)-2-oxo-, trans
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Brand
- Adipogen Life Sciences
- AHH
- AK Scientific
- Alfa Aesar
- ApexBio Technology
- AvaChem
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- y0000515
- 5mg
- 10mg
- y0000516
- 1mg
- 50
- 10
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 0.5g
- 500mg
- 1g
- 5g
- 10g
- 25g
- 10mM(in 1mL DMSO)
- ManufacturerAdipogen Life Sciences
- Product numberCDX-G0208-G001
- Product descriptionGlimepiride ≥98%(HPLC)
- Packaging1g
- Price$129
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberAPI-1398
- Product descriptionGlimepiride 98%
- Packaging0.5g
- Price$470
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberG193
- Product descriptionGlimepiride
- Packaging1g
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ10973
- Product descriptionGlimepiride
- Packaging5g
- Price$468
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ62032
- Product descriptionGlimepiride
- Packaging100mg
- Price$77.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ62032
- Product descriptionGlimepiride
- Packaging1g
- Price$336.65
- Updated2024-03-01
- Buy
- ManufacturerApexBio Technology
- Product numberA4033
- Product descriptionGlimepiride
- Packaging10mM(in 1mL DMSO)
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4033
- Product descriptionGlimepiride
- Packaging1g
- Price$79
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4033
- Product descriptionGlimepiride
- Packaging5g
- Price$285
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1669
- Product descriptionGlimepiride
- Packaging25mg
- Price$29
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1669
- Product descriptionGlimepiride
- Packaging100mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1669
- Product descriptionGlimepiride
- Packaging1g
- Price$69
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1669
- Product descriptionGlimepiride
- Packaging5g
- Price$129
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1669
- Product descriptionGlimepiride
- Packaging10g
- Price$189
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1669
- Product descriptionGlimepiride
- Packaging25g
- Price$289
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBG164507
- Product descriptionGlimepiride
- Packaging100mg
- Price$50
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | CDX-G0208-G001 | Glimepiride ≥98%(HPLC) | 1g | $129 | 2021-12-16 | Buy |
| AHH | API-1398 | Glimepiride 98% | 0.5g | $470 | 2021-12-16 | Buy |
| AK Scientific | G193 | Glimepiride | 1g | $96 | 2021-12-16 | Buy |
| AK Scientific | J10973 | Glimepiride | 5g | $468 | 2021-12-16 | Buy |
| Alfa Aesar | J62032 | Glimepiride | 100mg | $77.65 | 2024-03-01 | Buy |
| Alfa Aesar | J62032 | Glimepiride | 1g | $336.65 | 2024-03-01 | Buy |
| ApexBio Technology | A4033 | Glimepiride | 10mM(in 1mL DMSO) | $60 | 2021-12-16 | Buy |
| ApexBio Technology | A4033 | Glimepiride | 1g | $79 | 2021-12-16 | Buy |
| ApexBio Technology | A4033 | Glimepiride | 5g | $285 | 2021-12-16 | Buy |
| AvaChem | 1669 | Glimepiride | 25mg | $29 | 2021-12-16 | Buy |
| AvaChem | 1669 | Glimepiride | 100mg | $39 | 2021-12-16 | Buy |
| AvaChem | 1669 | Glimepiride | 1g | $69 | 2021-12-16 | Buy |
| AvaChem | 1669 | Glimepiride | 5g | $129 | 2021-12-16 | Buy |
| AvaChem | 1669 | Glimepiride | 10g | $189 | 2021-12-16 | Buy |
| AvaChem | 1669 | Glimepiride | 25g | $289 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BG164507 | Glimepiride | 100mg | $50 | 2021-12-16 | Buy |
Properties
Melting point :212.2-214.5 °C
Density :1.29±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: >10 mg/mL
pka :5.10±0.10(Predicted)
form :solid
color :white
Merck :14,4440
BCS Class :2
CAS DataBase Reference :93479-97-1(CAS DataBase Reference)
EPA Substance Registry System :1H-Pyrrole-1-carboxamide, 3-ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(trans- 4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo- (93479-97-1)
Density :1.29±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: >10 mg/mL
pka :5.10±0.10(Predicted)
form :solid
color :white
Merck :14,4440
BCS Class :2
CAS DataBase Reference :93479-97-1(CAS DataBase Reference)
EPA Substance Registry System :1H-Pyrrole-1-carboxamide, 3-ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(trans- 4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo- (93479-97-1)
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Glimepiride (original trade name Amaryl) is an orally available medium-to-long-acting sulfonylurea antidiabetic drug. It is sometimes classified as either the first third-generation sulfonylurea, or as second-generation. Like all sulfonylureas, glimepiride acts as an insulin secretagogue. It lowers blood sugar by stimulating the release of insulin from functioning pancreatic beta cells and by increasing sensitivity of peripheral tissues to insulin. Glimepiride likely binds to ATP-sensitive potassium channel receptors on the pancreatic cell surface, reducing potassium conductance and causing depolarization of the membrane. Membrane depolarization stimulates calcium ion influx through voltage-sensitive calcium channels. This increase in intracellular calcium ion concentration induces the secretion of insulin. Glimepiride is mainly used to treat patients with type 2 diabetes and can also decrease the chances that someone will develop complications of type 2 diabetes, such as kidney damage, blindness, nerve problems, loss of limbs, sexual function problems and heart attack or stroke. The drug was approved by the FDA in 1995 and is manufactured by Sanofi-Aventis. It can be used along with proper diet and exercise program and may also be used alone or with other antidiabetic medicines if need. The drug is available only with your doctor's prescription.Related product price
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Suppliers and manufacturers
Capot Chemical Co.,Ltd.
Henan Tianfu Chemical Co.,Ltd.
Hefei TNJ Chemical Industry Co.,Ltd.
