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ChemicalBook >> CAS DataBase List >> Gemfibrozil

Gemfibrozil

Gemfibrozil price.
  • $5 - $2055.9
  • Product name: Gemfibrozil
  • CAS: 25812-30-0
  • MF: C15H22O3
  • MW: 250.33
  • EINECS:247-280-2
  • MDL Number:MFCD00079335
  • Synonyms:PENTANOIC ACID, 5-(2,5-DIMETHYLPHENOXY)-2,2-DIMETHYL-;5-(2,5-DIMETHYLPHYLPHENOXY)-2,2-DIMETHYLPENTANOIC ACID;5-(2,5-DIMETHYL-PHENOXY)-2,2-DIMETHYL-PENTANOIC ACID;2,2-DIMETHYL-5-[2,5-DIMETHYL-PHENOXY]PENTANOIC ACID;2,2-DIMETHYL-5-(2,5-XYLYLOXY) VALERIC ACID;GEMFIBROZIL;Gemcitabine intermediates;5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic Acid, CI-719, Decrelip, Genlip, Gevilon, Lipozid, Lpur, Lopid
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  • AHH
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Aronis compounds
  • Biorbyt Ltd
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  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 100μg
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  • 10mM(in 1mL DMSO)
  • 50mg
  • y0000513
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  • ManufacturerAHH
  • Product numberAPI-1649
  • Product descriptionGemfibrozil 98%
  • Packaging1000g
  • Price$490
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberH900
  • Product descriptionGemfibrozil
  • Packaging25g
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA640007
  • Product descriptionGemfibrozil 98%
  • Packaging100mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA640007
  • Product descriptionGemfibrozil 98%
  • Packaging5g
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA640007
  • Product descriptionGemfibrozil 98%
  • Packaging10g
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA640007
  • Product descriptionGemfibrozil 98%
  • Packaging25g
  • Price$26
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA640007
  • Product descriptionGemfibrozil 98%
  • Packaging100g
  • Price$74
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA640007
  • Product descriptionGemfibrozil 98%
  • Packaging500g
  • Price$263
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002816
  • Product descriptionGemfibrozil 95.00%
  • Packaging1G
  • Price$704.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002816
  • Product descriptionGemfibrozil 95.00%
  • Packaging10G
  • Price$2055.9
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1947
  • Product descriptionGemfibrozil
  • Packaging100mg
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1947
  • Product descriptionGemfibrozil
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1947
  • Product descriptionGemfibrozil
  • Packaging500mg
  • Price$86
  • Updated2021-12-16
  • Buy
  • ManufacturerAronis compounds
  • Product numberBBC/228
  • Product description5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoicacid
  • Packaging1g
  • Price$35
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb593446
  • Product descriptionGemfibrozil
  • Packaging50μg
  • Price$425
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb134440
  • Product descriptionGemfibrozil (Lopid) >99%
  • Packaging100mg
  • Price$510
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1649 Gemfibrozil 98% 1000g $490 2021-12-16 Buy
AK Scientific H900 Gemfibrozil 25g $70 2021-12-16 Buy
Ambeed A640007 Gemfibrozil 98% 100mg $5 2021-12-16 Buy
Ambeed A640007 Gemfibrozil 98% 5g $6 2021-12-16 Buy
Ambeed A640007 Gemfibrozil 98% 10g $11 2021-12-16 Buy
Ambeed A640007 Gemfibrozil 98% 25g $26 2021-12-16 Buy
Ambeed A640007 Gemfibrozil 98% 100g $74 2021-12-16 Buy
Ambeed A640007 Gemfibrozil 98% 500g $263 2021-12-16 Buy
American Custom Chemicals Corporation API0002816 Gemfibrozil 95.00% 1G $704.55 2021-12-16 Buy
American Custom Chemicals Corporation API0002816 Gemfibrozil 95.00% 10G $2055.9 2021-12-16 Buy
ApexBio Technology B1947 Gemfibrozil 100mg $42 2021-12-16 Buy
ApexBio Technology B1947 Gemfibrozil 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology B1947 Gemfibrozil 500mg $86 2021-12-16 Buy
Aronis compounds BBC/228 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoicacid 1g $35 2021-12-16 Buy
Biorbyt Ltd orb593446 Gemfibrozil 50μg $425 2021-12-16 Buy
Biorbyt Ltd orb134440 Gemfibrozil (Lopid) >99% 100mg $510 2021-12-16 Buy

Properties

Melting point :61-63°C
Boiling point :158-159 C
Density :1.1109 (rough estimate)
refractive index :1.5020 (estimate)
storage temp. :2-8°C
solubility :Practically insoluble in water, very soluble in methylene chloride, freely soluble in anhydrous ethanol and in methanol.
form :powder
pka :4.75±0.45(Predicted)
color :White to Off-White
Water Solubility :>0.5g/L(temperature not stated)
Merck :14,4388
BCS Class :2
CAS DataBase Reference :25812-30-0(CAS DataBase Reference)
IARC :3 (Vol. 66) 1996
EPA Substance Registry System :Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl- (25812-30-0)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Gemfibrozil is a fibrate that activates peroxisome proliferator-activator α (PPARα, EC50 = 193 μM) with 100% efficacy. It also activates PPARγ (EC50 = 148 μM), but with only 79% efficacy. Presumably through its effects on PPARα, gemfibrozil lowers triglycerides and increases high density lipoprotein cholesterol levels and is used in the context of atherogenic dyslipidemia. Gemfibrozil strongly binds liver fatty acid-binding protein (Ki = 1.8 μM). Phase II metabolites of gemfibrozil inhibit certain cytochrome P450 isoforms, increasing drug-drug interaction risks.

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