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ChemicalBook >> CAS DataBase List >> GZD 824

GZD 824

GZD 824 price.
  • $30 - $2691.1
  • Product name: GZD 824
  • CAS: 1257628-77-5
  • MF: C29H27F3N6O
  • MW: 532.56
  • EINECS:
  • MDL Number:MFCD26142930
  • Synonyms:4-Methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[2-(1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]benzamide;3-(2-(1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide;GZD8824;GZD824;GZD-824;GZD 824;GZD-824 Free;GZD 824;GZD824;GZD-824
22 prices
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Brand
  • Activate Scientific
  • AK Scientific
  • Ambeed
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
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  • 10mg
  • 25mg
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  • 250mg
  • 1g
  • 1000mg
  • ManufacturerActivate Scientific
  • Product numberAS117572
  • Product descriptionGZD824 98+%
  • Packaging5mg
  • Price$212
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS117572
  • Product descriptionGZD824 98+%
  • Packaging1mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number8976DH
  • Product descriptionCID51038269
  • Packaging5mg
  • Price$252
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA163539
  • Product descriptionGZD824 98+%
  • Packaging1mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA163539
  • Product descriptionGZD824 98+%
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA163539
  • Product descriptionGZD824 98+%
  • Packaging10mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA163539
  • Product descriptionGZD824 98+%
  • Packaging100mg
  • Price$142
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA163539
  • Product descriptionGZD824 98+%
  • Packaging250mg
  • Price$284
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA163539
  • Product descriptionGZD824 98+%
  • Packaging1g
  • Price$709
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181016
  • Product descriptionGZD824 >98%
  • Packaging100mg
  • Price$690.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181016
  • Product descriptionGZD824 >98%
  • Packaging250mg
  • Price$1356.6
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181016
  • Product descriptionGZD824 >98%
  • Packaging1000mg
  • Price$2691.1
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21508
  • Product descriptionGZD-824 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21508
  • Product descriptionGZD-824 ≥98%
  • Packaging5mg
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21508
  • Product descriptionGZD-824 ≥98%
  • Packaging10mg
  • Price$243
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21508
  • Product descriptionGZD-824 ≥98%
  • Packaging25mg
  • Price$456
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Activate Scientific AS117572 GZD824 98+% 5mg $212 2021-12-16 Buy
Activate Scientific AS117572 GZD824 98+% 1mg $119 2021-12-16 Buy
AK Scientific 8976DH CID51038269 5mg $252 2021-12-16 Buy
Ambeed A163539 GZD824 98+% 1mg $30 2021-12-16 Buy
Ambeed A163539 GZD824 98+% 5mg $50 2021-12-16 Buy
Ambeed A163539 GZD824 98+% 10mg $65 2021-12-16 Buy
Ambeed A163539 GZD824 98+% 100mg $142 2021-12-16 Buy
Ambeed A163539 GZD824 98+% 250mg $284 2021-12-16 Buy
Ambeed A163539 GZD824 98+% 1g $709 2021-12-16 Buy
Biorbyt Ltd orb181016 GZD824 >98% 100mg $690.2 2021-12-16 Buy
Biorbyt Ltd orb181016 GZD824 >98% 250mg $1356.6 2021-12-16 Buy
Biorbyt Ltd orb181016 GZD824 >98% 1000mg $2691.1 2021-12-16 Buy
Cayman Chemical 21508 GZD-824 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 21508 GZD-824 ≥98% 5mg $139 2024-03-01 Buy
Cayman Chemical 21508 GZD-824 ≥98% 10mg $243 2024-03-01 Buy
Cayman Chemical 21508 GZD-824 ≥98% 25mg $456 2024-03-01 Buy

Properties

Boiling point :630.4±55.0 °C(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : ≥ 100 mg/mL (187.77 mM)
form :A crystalline solid
pka :9.04±0.40(Predicted)
color :Off-white to yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

GZD-824 is an orally available inhibitor of a broad spectrum of Bcr/Abl tyrosine kinase mutants including T315I (IC50s = 0.34 and 0.68 nM for wild-type Bcr/Abl and Bcr/AblT315I, respectively). It has been shown to suppress the proliferation of Bcr/Abl-positive K562 and Ku812 human chronic myelogenous leukemia cells (IC50s = 0.2 and 0.13 nM, respectively) and induce tumor regression in mouse xenograft tumor models driven by either wild-type or mutant Bcr/Abl.

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