GZD 824
- $30 - $2691.1
- Product name: GZD 824
- CAS: 1257628-77-5
- MF: C29H27F3N6O
- MW: 532.56
- EINECS:
- MDL Number:MFCD26142930
- Synonyms:4-Methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[2-(1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]benzamide;3-(2-(1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide;GZD8824;GZD824;GZD-824;GZD 824;GZD-824 Free;GZD 824;GZD824;GZD-824
22 prices
Selected condition:
Brand
- Activate Scientific
- AK Scientific
- Ambeed
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 100mg
- 250mg
- 1g
- 1000mg
- ManufacturerActivate Scientific
- Product numberAS117572
- Product descriptionGZD824 98+%
- Packaging5mg
- Price$212
- Updated2021-12-16
- Buy
- ManufacturerActivate Scientific
- Product numberAS117572
- Product descriptionGZD824 98+%
- Packaging1mg
- Price$119
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8976DH
- Product descriptionCID51038269
- Packaging5mg
- Price$252
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA163539
- Product descriptionGZD824 98+%
- Packaging1mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA163539
- Product descriptionGZD824 98+%
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA163539
- Product descriptionGZD824 98+%
- Packaging10mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA163539
- Product descriptionGZD824 98+%
- Packaging100mg
- Price$142
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA163539
- Product descriptionGZD824 98+%
- Packaging250mg
- Price$284
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA163539
- Product descriptionGZD824 98+%
- Packaging1g
- Price$709
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181016
- Product descriptionGZD824 >98%
- Packaging100mg
- Price$690.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181016
- Product descriptionGZD824 >98%
- Packaging250mg
- Price$1356.6
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181016
- Product descriptionGZD824 >98%
- Packaging1000mg
- Price$2691.1
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21508
- Product descriptionGZD-824 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21508
- Product descriptionGZD-824 ≥98%
- Packaging5mg
- Price$139
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21508
- Product descriptionGZD-824 ≥98%
- Packaging10mg
- Price$243
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21508
- Product descriptionGZD-824 ≥98%
- Packaging25mg
- Price$456
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Activate Scientific | AS117572 | GZD824 98+% | 5mg | $212 | 2021-12-16 | Buy |
Activate Scientific | AS117572 | GZD824 98+% | 1mg | $119 | 2021-12-16 | Buy |
AK Scientific | 8976DH | CID51038269 | 5mg | $252 | 2021-12-16 | Buy |
Ambeed | A163539 | GZD824 98+% | 1mg | $30 | 2021-12-16 | Buy |
Ambeed | A163539 | GZD824 98+% | 5mg | $50 | 2021-12-16 | Buy |
Ambeed | A163539 | GZD824 98+% | 10mg | $65 | 2021-12-16 | Buy |
Ambeed | A163539 | GZD824 98+% | 100mg | $142 | 2021-12-16 | Buy |
Ambeed | A163539 | GZD824 98+% | 250mg | $284 | 2021-12-16 | Buy |
Ambeed | A163539 | GZD824 98+% | 1g | $709 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181016 | GZD824 >98% | 100mg | $690.2 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181016 | GZD824 >98% | 250mg | $1356.6 | 2021-12-16 | Buy |
Biorbyt Ltd | orb181016 | GZD824 >98% | 1000mg | $2691.1 | 2021-12-16 | Buy |
Cayman Chemical | 21508 | GZD-824 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 21508 | GZD-824 ≥98% | 5mg | $139 | 2024-03-01 | Buy |
Cayman Chemical | 21508 | GZD-824 ≥98% | 10mg | $243 | 2024-03-01 | Buy |
Cayman Chemical | 21508 | GZD-824 ≥98% | 25mg | $456 | 2024-03-01 | Buy |
Properties
Boiling point :630.4±55.0 °C(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : ≥ 100 mg/mL (187.77 mM)
form :A crystalline solid
pka :9.04±0.40(Predicted)
color :Off-white to yellow
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : ≥ 100 mg/mL (187.77 mM)
form :A crystalline solid
pka :9.04±0.40(Predicted)
color :Off-white to yellow
Safety Information
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Description
GZD-824 is an orally available inhibitor of a broad spectrum of Bcr/Abl tyrosine kinase mutants including T315I (IC50s = 0.34 and 0.68 nM for wild-type Bcr/Abl and Bcr/AblT315I, respectively). It has been shown to suppress the proliferation of Bcr/Abl-positive K562 and Ku812 human chronic myelogenous leukemia cells (IC50s = 0.2 and 0.13 nM, respectively) and induce tumor regression in mouse xenograft tumor models driven by either wild-type or mutant Bcr/Abl.More related product prices
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