Fosaprepitant dimeglumine
- $5 - $4990
- Product name: Fosaprepitant dimeglumine
- CAS: 265121-04-8
- MF: C30H39F7N5O11P
- MW: 809.63
- EINECS:682-419-4
- MDL Number:MFCD23102059
- Synonyms:Phosphonic acid, (3-(((2R,3S)-2-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-morpholinyl)methyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl)-, compd. with 1-deoxy-1-(methylamino)-D-glucitol (1:2);Unii-D35fm8T64x;[3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-Morpholinyl]Methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate 1-Deoxy-1-(MethylaMino)-D-glucitol;1-Deoxy-1-(MethylaMino)-D-glucitol [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-Morpholinyl]Methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate;1-DEOXY-1-(METHYLAMINO)-D-GLUCITOL [[(2R,3S]-2-[(1R)-1-[3,5-BIS (TRIFLUOROMETHYL)PHENYL] PHENYL]ETHOXY]-(4-FLUOROPHENYL);3-[2(R)-[1(R)-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3(S)-(4-fluorophenyl)Morpholin-4-ylMethyl]-5-oxo-4,5-dihydro-1H-1,2,4-triazole-1-phosphinic acid bis(N-Methyl-D-glucaMine) salt;Fosaprepitant diMegluMine salt;Fosaprepitant dimeglumine, >=99%
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Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Chemtos
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500mg
- 1g
- 2g
- 5g
- ManufacturerAK Scientific
- Product numberJ11396
- Product descriptionFosaprepitantdimeglumine
- Packaging10mg
- Price$226
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA455841
- Product descriptionFosaprepitantdimeglumine 98+%
- Packaging5mg
- Price$6
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA455841
- Product descriptionFosaprepitantdimeglumine 98+%
- Packaging10mg
- Price$8
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA455841
- Product descriptionFosaprepitantdimeglumine 98+%
- Packaging50mg
- Price$19
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA455841
- Product descriptionFosaprepitantdimeglumine 98+%
- Packaging100mg
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA455841
- Product descriptionFosaprepitantdimeglumine 98+%
- Packaging250mg
- Price$47
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA455841
- Product descriptionFosaprepitantdimeglumine 98+%
- Packaging1g
- Price$126
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA455841
- Product descriptionFosaprepitantdimeglumine 98+%
- Packaging5g
- Price$423
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB2145
- Product descriptionFosaprepitantdimegluminesalt
- Packaging50mg
- Price$485
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS564407
- Product descriptionFosaprepitantdimeglumine ≥98%
- Packaging1mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS564407
- Product descriptionFosaprepitantdimeglumine ≥98%
- Packaging5mg
- Price$6
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS564407
- Product descriptionFosaprepitantdimeglumine ≥98%
- Packaging10mg
- Price$8
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS564407
- Product descriptionFosaprepitantdimeglumine ≥98%
- Packaging50mg
- Price$13
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS564407
- Product descriptionFosaprepitantdimeglumine ≥98%
- Packaging100mg
- Price$19
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS564407
- Product descriptionFosaprepitantdimeglumine ≥98%
- Packaging250mg
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS564407
- Product descriptionFosaprepitantdimeglumine ≥98%
- Packaging1g
- Price$91
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | J11396 | Fosaprepitantdimeglumine | 10mg | $226 | 2021-12-16 | Buy |
Ambeed | A455841 | Fosaprepitantdimeglumine 98+% | 5mg | $6 | 2021-12-16 | Buy |
Ambeed | A455841 | Fosaprepitantdimeglumine 98+% | 10mg | $8 | 2021-12-16 | Buy |
Ambeed | A455841 | Fosaprepitantdimeglumine 98+% | 50mg | $19 | 2021-12-16 | Buy |
Ambeed | A455841 | Fosaprepitantdimeglumine 98+% | 100mg | $28 | 2021-12-16 | Buy |
Ambeed | A455841 | Fosaprepitantdimeglumine 98+% | 250mg | $47 | 2021-12-16 | Buy |
Ambeed | A455841 | Fosaprepitantdimeglumine 98+% | 1g | $126 | 2021-12-16 | Buy |
Ambeed | A455841 | Fosaprepitantdimeglumine 98+% | 5g | $423 | 2021-12-16 | Buy |
ApexBio Technology | B2145 | Fosaprepitantdimegluminesalt | 50mg | $485 | 2021-12-16 | Buy |
Arctom | AS564407 | Fosaprepitantdimeglumine ≥98% | 1mg | $5 | 2021-12-16 | Buy |
Arctom | AS564407 | Fosaprepitantdimeglumine ≥98% | 5mg | $6 | 2021-12-16 | Buy |
Arctom | AS564407 | Fosaprepitantdimeglumine ≥98% | 10mg | $8 | 2021-12-16 | Buy |
Arctom | AS564407 | Fosaprepitantdimeglumine ≥98% | 50mg | $13 | 2021-12-16 | Buy |
Arctom | AS564407 | Fosaprepitantdimeglumine ≥98% | 100mg | $19 | 2021-12-16 | Buy |
Arctom | AS564407 | Fosaprepitantdimeglumine ≥98% | 250mg | $35 | 2021-12-16 | Buy |
Arctom | AS564407 | Fosaprepitantdimeglumine ≥98% | 1g | $91 | 2021-12-16 | Buy |
Properties
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :≥50.24 mg/mL in DMSO; insoluble in EtOH; ≥13.16 mg/mL in H2O with ultrasonic
form :Powder
pka :Fosaprepitant dimeglumine has four functional groups which have pKa values of 3.05 ± 0.03, 4.92 ± 0.02, 9.67 ± 0.01 and 10.59 ± 0.03. The pka value of 3.05 corresponds to the morpholinium group, the pka of 4.92 corresponds to the monophosphonate group, the pka of 9.67 corresponds to the meglumine counter ion, and the pka of 10.59 corresponds to the triazolinone NH group.
color :White to off-white
solubility :≥50.24 mg/mL in DMSO; insoluble in EtOH; ≥13.16 mg/mL in H2O with ultrasonic
form :Powder
pka :Fosaprepitant dimeglumine has four functional groups which have pKa values of 3.05 ± 0.03, 4.92 ± 0.02, 9.67 ± 0.01 and 10.59 ± 0.03. The pka value of 3.05 corresponds to the morpholinium group, the pka of 4.92 corresponds to the monophosphonate group, the pka of 9.67 corresponds to the meglumine counter ion, and the pka of 10.59 corresponds to the triazolinone NH group.
color :White to off-white
Safety Information
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Signal word: | Warning | |||||||||||||||||||||
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Description
Fosaprepitant dimeglumine is a water-soluble prodrug form of the neurokinin-1 receptor antagonist aprepitant. Formulations containing fosaprepitant dimeglumine have been used to prevent chemotherapy-induced nausea and vomiting.Related product price
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Suppliers and manufacturers
Shanghai Daken Advanced Materials Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
Nanjing ChemLin Chemical Industry Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
Lianyungang happen teng technology co., LTD