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ChemicalBook >> CAS DataBase List >> Ezetimibe

Ezetimibe

Ezetimibe price.
  • $5 - $1270
  • Product name: Ezetimibe
  • CAS: 163222-33-1
  • MF: C24H21F2NO3
  • MW: 409.43
  • EINECS:682-606-0
  • MDL Number:MFCD00937872
  • Synonyms:Ticagrelor and its interMediate;Ezetimibe 1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxy-propyl]-4-(4-hydroxyphenyl)-azetidin-2-one;zetia/vytorin;SCH 60969;Ezetimibe, >=99%;(3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azeti;1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxy-propyl]-4-(4-hydroxyphenyl)-azetidin-2-one;EZETIMIBE
53 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 10MG
  • 10mM(in 1mL DMSO)
  • 5mg
  • 20mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • 5g
  • 10g
  • 25g
  • 100g
  • ManufacturerAK Scientific
  • Product numberE190
  • Product descriptionEzetimibe
  • Packaging250mg
  • Price$37
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ51051
  • Product descriptionEzetimibe
  • Packaging5g
  • Price$1270
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA124629
  • Product descriptionEzetimibe 98+%
  • Packaging50mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA124629
  • Product descriptionEzetimibe 98+%
  • Packaging100mg
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA124629
  • Product descriptionEzetimibe 98+%
  • Packaging250mg
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA124629
  • Product descriptionEzetimibe 98+%
  • Packaging1g
  • Price$26
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA124629
  • Product descriptionEzetimibe 98+%
  • Packaging5g
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA124629
  • Product descriptionEzetimibe 98+%
  • Packaging10g
  • Price$173
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA124629
  • Product descriptionEzetimibe 98+%
  • Packaging25g
  • Price$404
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA124629
  • Product descriptionEzetimibe 98+%
  • Packaging100g
  • Price$1105
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002672
  • Product descriptionEZETIMIBE 95.00%
  • Packaging10MG
  • Price$704.55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8430
  • Product descriptionEzetimibe
  • Packaging50mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8430
  • Product descriptionEzetimibe
  • Packaging10mM(in 1mL DMSO)
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8430
  • Product descriptionEzetimibe
  • Packaging100mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS440820
  • Product descriptionEzetimibe ≥98%
  • Packaging25g
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS440820
  • Product descriptionEzetimibe ≥98%
  • Packaging10g
  • Price$180
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific E190 Ezetimibe 250mg $37 2021-12-16 Buy
AK Scientific J51051 Ezetimibe 5g $1270 2021-12-16 Buy
Ambeed A124629 Ezetimibe 98+% 50mg $5 2021-12-16 Buy
Ambeed A124629 Ezetimibe 98+% 100mg $7 2021-12-16 Buy
Ambeed A124629 Ezetimibe 98+% 250mg $11 2021-12-16 Buy
Ambeed A124629 Ezetimibe 98+% 1g $26 2021-12-16 Buy
Ambeed A124629 Ezetimibe 98+% 5g $96 2021-12-16 Buy
Ambeed A124629 Ezetimibe 98+% 10g $173 2021-12-16 Buy
Ambeed A124629 Ezetimibe 98+% 25g $404 2021-12-16 Buy
Ambeed A124629 Ezetimibe 98+% 100g $1105 2021-12-16 Buy
American Custom Chemicals Corporation API0002672 EZETIMIBE 95.00% 10MG $704.55 2021-12-16 Buy
ApexBio Technology A8430 Ezetimibe 50mg $70 2021-12-16 Buy
ApexBio Technology A8430 Ezetimibe 10mM(in 1mL DMSO) $80 2021-12-16 Buy
ApexBio Technology A8430 Ezetimibe 100mg $100 2021-12-16 Buy
Arctom AS440820 Ezetimibe ≥98% 25g $400 2021-12-16 Buy
Arctom AS440820 Ezetimibe ≥98% 10g $180 2021-12-16 Buy

Properties

Melting point :164-166°C
alpha :D22 -33.9° (c = 3 in methanol)
Boiling point :654.9±55.0 °C(Predicted)
Density :1.334±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 15 mg/ml)
pka :9.72±0.30(Predicted)
form :powder
color :White or off-white
BCS Class :2
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1
InChIKey :OLNTVTPDXPETLC-XPWALMASSA-N
SMILES :N1(C2=CC=C(F)C=C2)[C@H](C2=CC=C(O)C=C2)[C@@H](CC[C@@H](C2=CC=C(F)C=C2)O)C1=O
CAS DataBase Reference :163222-33-1(CAS DataBase Reference)
EPA Substance Registry System :2-Azetidinone, 1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-, (3R,4S)- (163222-33-1)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.
P391 Collect spillage. Hazardous to the aquatic environment
P501 Dispose of contents/container to..…

Description

Ezetimibe is ananti-hyperlipidemic drug used for lowering the plasma cholesterol levels. It is indicated as an adjunctive therapy to diet for the reduction of high-level total-C, LDL-C, and ApoB in patients suffering primary (heterozygous familial and non-familial) hypercholesterolemia. It is also used in combination therapy with HMG-CoA reductase inhibitors.Ezetimibe does not inhibit the cholesterol synthesis in the liver, or increase bile acid excretion.It takes effect throughacting at the brush border of the small intestine and inhibiting the absorption of cholesterol, further leading to a decrease in the delivery of intestinal cholesterol to the liver. This causes a reduction of hepatic cholesterol stores and an increase in clearance of blood cholesterol.

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