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ChemicalBook >> CAS DataBase List >> Daminozide

Daminozide

Daminozide price.
  • $16.8 - $774
  • Product name: Daminozide
  • CAS: 1596-84-5
  • MF: C6H12N2O3
  • MW: 160.17
  • EINECS:216-485-9
  • MDL Number:MFCD00002787
  • Synonyms:4-(2,2-diMethylhydrazinyl)-4-oxobutanoic acid;DAMINOZIDE, 1GM, NEAT;DAMINOZID PESTANAL (SUCCINIC ACID MONO-(;SUCCINIC ACID 2,2-DIMETHYLHYDRAZIDE*PLAN T CELL CULT;Alar(B-9)Gr-(Daminozide)(SuccinicAcid2,2-DimethylHydrazide);Daminozide(B9);Alar(B-9)Gr;N-(DIMETHYLAMINO)SUCCINAMIC ACID
31 prices
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Brand
  • AK Scientific
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
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  • TCI Chemical
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  • TRC
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  • 10mM(in 1mL DMSO)
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  • 1kg
  • ManufacturerAK Scientific
  • Product numberJ99573
  • Product description3-(N',N'-dimethylhydrazinecarbonyl)propanoicacid
  • Packaging100g
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberS346
  • Product description3-(N',N'-dimethylhydrazinecarbonyl)propanoicacid
  • Packaging100g
  • Price$107
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ99573
  • Product description3-(N',N'-dimethylhydrazinecarbonyl)propanoicacid
  • Packaging1kg
  • Price$480
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3348
  • Product descriptionDaminozide
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA3348
  • Product descriptionDaminozide
  • Packaging25g
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3348
  • Product descriptionDaminozide
  • Packaging50g
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD33787
  • Product descriptionDaminozide
  • Packaging100g
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD33787
  • Product descriptionDaminozide
  • Packaging1kg
  • Price$490
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number12033
  • Product descriptionDaminozide ≥95%
  • Packaging5g
  • Price$22
  • Updated2023-06-20
  • Buy
  • ManufacturerCayman Chemical
  • Product number12033
  • Product descriptionDaminozide ≥95%
  • Packaging10g
  • Price$36
  • Updated2023-06-20
  • Buy
  • ManufacturerCayman Chemical
  • Product number12033
  • Product descriptionDaminozide ≥95%
  • Packaging25g
  • Price$83
  • Updated2023-06-20
  • Buy
  • ManufacturerChem-Impex
  • Product number01480
  • Product descriptionDaminozide,99%(Assay) 99%(Assay)
  • Packaging5G
  • Price$16.8
  • Updated2021-12-16
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  • ManufacturerChem-Impex
  • Product number01480
  • Product descriptionDaminozide,≥99%(Assay) ≥99%(Assay)
  • Packaging25G
  • Price$34.94
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number01480
  • Product descriptionDaminozide,≥99%(Assay) ≥99%(Assay)
  • Packaging100G
  • Price$93.18
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number01480
  • Product descriptionDaminozide,99%(Assay) 99%(Assay)
  • Packaging250G
  • Price$184.8
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number01480
  • Product descriptionDaminozide,≥99%(Assay) ≥99%(Assay)
  • Packaging1KG
  • Price$698.88
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J99573 3-(N',N'-dimethylhydrazinecarbonyl)propanoicacid 100g $80 2021-12-16 Buy
AK Scientific S346 3-(N',N'-dimethylhydrazinecarbonyl)propanoicacid 100g $107 2021-12-16 Buy
AK Scientific J99573 3-(N',N'-dimethylhydrazinecarbonyl)propanoicacid 1kg $480 2021-12-16 Buy
ApexBio Technology A3348 Daminozide 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology A3348 Daminozide 25g $65 2021-12-16 Buy
ApexBio Technology A3348 Daminozide 50g $99 2021-12-16 Buy
Biosynth Carbosynth FD33787 Daminozide 100g $75 2021-12-16 Buy
Biosynth Carbosynth FD33787 Daminozide 1kg $490 2021-12-16 Buy
Cayman Chemical 12033 Daminozide ≥95% 5g $22 2023-06-20 Buy
Cayman Chemical 12033 Daminozide ≥95% 10g $36 2023-06-20 Buy
Cayman Chemical 12033 Daminozide ≥95% 25g $83 2023-06-20 Buy
Chem-Impex 01480 Daminozide,99%(Assay) 99%(Assay) 5G $16.8 2021-12-16 Buy
Chem-Impex 01480 Daminozide,≥99%(Assay) ≥99%(Assay) 25G $34.94 2021-12-16 Buy
Chem-Impex 01480 Daminozide,≥99%(Assay) ≥99%(Assay) 100G $93.18 2021-12-16 Buy
Chem-Impex 01480 Daminozide,99%(Assay) 99%(Assay) 250G $184.8 2021-12-16 Buy
Chem-Impex 01480 Daminozide,≥99%(Assay) ≥99%(Assay) 1KG $698.88 2021-12-16 Buy

Properties

Melting point :162-164 °C(lit.)
Boiling point :286.06°C (rough estimate)
Density :1.2751 (rough estimate)
refractive index :1.4500 (estimate)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 50 mg/ml), or in Water (up to 20 mg/ml with warming).
pka :5.59±0.10(Predicted)
form :White powder
color :White crystalline
Water Solubility :100 g/L
Merck :14,2810
BRN :1863230
Stability :Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, strong acids, wetting agents, oils, copper-containing compounds.
InChIKey :NOQGZXFMHARMLW-UHFFFAOYSA-N
CAS DataBase Reference :1596-84-5(CAS DataBase Reference)
NIST Chemistry Reference :Butanedioic acid, mono(2,2-dimethylhydrazide)(1596-84-5)
EPA Substance Registry System :Daminozide (1596-84-5)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Daminozide is a highly selective inhibitor of the human 2-oxoglutarate (JmjC) histone demethylases KDM2A, PHF8, and KDM7A with IC50 values of 1.5, 0.55, and 2.1 μM, respectively. When tested for inhibition of other demethylase subfamily members (KDM3, KDM4, KDM5, KDM6) and other 2OG oxygenases (FIH, PHD2, BBOX1), daminozide was considerably less potent (IC50s > 100 μM). Daminozide is known to retard plant growth and was widely used in the 1960s for agricultural and horticultural applications to control plant size and fruit ripening before it was withdrawn because of carcinogenicity concerns.

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