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ChemicalBook >> CAS DataBase List >> DECAMETHONIUM BROMIDE

DECAMETHONIUM BROMIDE

DECAMETHONIUM BROMIDE price.
  • $28 - $1284.49
  • Product name: DECAMETHONIUM BROMIDE
  • CAS: 541-22-0
  • MF: C16H38Br2N2
  • MW: 418.29
  • EINECS:208-772-2
  • MDL Number:MFCD00011779
  • Synonyms:1,10-Decanediaminium,N,N,N,N’,N’,N’-hexamethyl-,dibromide ;10-decanediaminium,n,n,n,n’,n’,n’-hexamethyl-dibromide ;decacuran ;decamethoniumdibromide ;decamethylene-1,10-bistrimethylammoniumdibromide ;decamethylenebis(trimethyl-ammoniudibromide ;1,10-Decanediaminium, N1,N1,N1,N10,N10,N10-hexamethyl-, bromide (1:2);dekamethoniumbromid
22 prices
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Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
Package
  • 10mM(in 1mL DMSO)
  • 1unit
  • 50MG
  • 1g
  • 5G
  • 10g
  • 25g
  • ManufacturerAK Scientific
  • Product number6379AF
  • Product descriptionDecamethonium Bromide
  • Packaging25g
  • Price$349
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008507
  • Product descriptionDECAMETHONIUM BROMIDE 95.00%
  • Packaging50MG
  • Price$224.7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008507
  • Product descriptionDECAMETHONIUM BROMIDE 95.00%
  • Packaging5G
  • Price$845.23
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008507
  • Product descriptionDECAMETHONIUM BROMIDE 95.00%
  • Packaging25G
  • Price$1284.49
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1601
  • Product descriptionDecamethonium Bromide
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1601
  • Product descriptionDecamethonium Bromide
  • Packaging5g
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1601
  • Product descriptionDecamethonium Bromide
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1601
  • Product descriptionDecamethonium Bromide
  • Packaging10g
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD61447
  • Product descriptionDecamethonium bromide
  • Packaging10g
  • Price$175
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD61447
  • Product descriptionDecamethonium bromide
  • Packaging25g
  • Price$375
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number24907
  • Product descriptionDecamethonium (bromide) ≥98%
  • Packaging1g
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24907
  • Product descriptionDecamethonium (bromide) ≥98%
  • Packaging5g
  • Price$78
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24907
  • Product descriptionDecamethonium (bromide) ≥98%
  • Packaging10g
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerChem-Impex
  • Product number37778
  • Product descriptionDecamethoniumbromide,98%(Assaybytitration) 98%(Assaybytitration)
  • Packaging5G
  • Price$69.44
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number37778
  • Product descriptionDecamethoniumbromide,98%(Assaybytitration) 98%(Assaybytitration)
  • Packaging25G
  • Price$229.6
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2678
  • Product descriptionDecamethonium Bromide >98.0%
  • Packaging25g
  • Price$160
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 6379AF Decamethonium Bromide 25g $349 2021-12-16 Buy
American Custom Chemicals Corporation API0008507 DECAMETHONIUM BROMIDE 95.00% 50MG $224.7 2021-12-16 Buy
American Custom Chemicals Corporation API0008507 DECAMETHONIUM BROMIDE 95.00% 5G $845.23 2021-12-16 Buy
American Custom Chemicals Corporation API0008507 DECAMETHONIUM BROMIDE 95.00% 25G $1284.49 2021-12-16 Buy
ApexBio Technology B1601 Decamethonium Bromide 1unit $28 2021-12-16 Buy
ApexBio Technology B1601 Decamethonium Bromide 5g $50 2021-12-16 Buy
ApexBio Technology B1601 Decamethonium Bromide 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology B1601 Decamethonium Bromide 10g $90 2021-12-16 Buy
Biosynth Carbosynth FD61447 Decamethonium bromide 10g $175 2021-12-16 Buy
Biosynth Carbosynth FD61447 Decamethonium bromide 25g $375 2021-12-16 Buy
Cayman Chemical 24907 Decamethonium (bromide) ≥98% 1g $32 2024-03-01 Buy
Cayman Chemical 24907 Decamethonium (bromide) ≥98% 5g $78 2024-03-01 Buy
Cayman Chemical 24907 Decamethonium (bromide) ≥98% 10g $139 2024-03-01 Buy
Chem-Impex 37778 Decamethoniumbromide,98%(Assaybytitration) 98%(Assaybytitration) 5G $69.44 2021-12-16 Buy
Chem-Impex 37778 Decamethoniumbromide,98%(Assaybytitration) 98%(Assaybytitration) 25G $229.6 2021-12-16 Buy
ChemScene CS-2678 Decamethonium Bromide >98.0% 25g $160 2021-12-16 Buy

Properties

Melting point :263-267 °C(lit.)
storage temp. :Inert atmosphere,Room Temperature
solubility :DMF: 2 mg/ml; DMSO: 16 mg/ml; Ethanol: 33 mg/ml; PBS (pH 7.2): 5 mg/ml
form :crystalline
color :off-white
Water Solubility :almost transparency
λmax :λ: 240 nm Amax: 0.04
λ: 250 nm Amax: 0.03
λ: 260 nm Amax: 0.02
λ: 500 nm Amax: 0.02 Merck :14,2847
BRN :3728288
Stability :Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference :541-22-0(CAS DataBase Reference)
EPA Substance Registry System :Decamethonium dibromide (541-22-0)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Decamethonium is a depolarizing neuromuscular blocking agent. It is a partial agonist of muscle-type nicotinic acetylcholine receptors (nAChRs). Decamethonium activates α1β1-containing adult mouse muscle-type nAChRs expressed in X. laevis oocytes with an EC50 value of 40 μM using voltage clamp electrophysiology. It is also a nondepolarizing antagonist of neuronal-type nAChRs, inhibiting mouse α7-, α3β2-, α3β4-, and α4β2-containing receptors with IC50 values of 7.4, 405, 28, and 59 μM, respectively. Decamethonoium is a competitive antagonist of α4β2-containing nAChRs expressed in SH-EP1 cells (IC50 = 52 μM for the human receptor). It also inhibits electric eel acetylcholinesterase (AChE) and blocks electrically-evoked tibialis muscle twitches in anesthetized cats with ED95 values of 35 and 70 μg/kg for cats under chloralose and ether anesthesia, respectively. Formulations containing decamethonium have been used to induce paralysis during anesthesia.

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