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ChemicalBook >> CAS DataBase List >> Clevidipine butyrate

Clevidipine butyrate

Clevidipine butyrate price.
  • $5 - $1686.3
  • Product name: Clevidipine butyrate
  • CAS: 167221-71-8
  • MF: C21H23Cl2NO6
  • MW: 456.32
  • EINECS:682-702-2
  • MDL Number:MFCD00940070
  • Synonyms:Methyl (1-oxobutoxy)methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dime thyl-3,5-pyridinedicarboxylate;4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-Pyridinedicarboxylic acid methyl (1-oxobutoxy)methyl ester;3,5-Pyridinedicarboxylicacid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, 3-methyl5-[(1-oxobutoxy)methyl] ester;Clevidipine butyrate;4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-diMethyl-3,5-pyridinedicarboxylic Acid 3-Methyl 5-[(1-Oxobutoxy)Methyl] Ester;Clevelox;H 324/38;rac-Clevidipine
36 prices
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  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • AvaChem
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • DC Chemicals
  • Labseeker
  • TCI Chemical
  • TRC
Package
  • 5MG
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  • 25mg
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  • 100mg
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  • 1g
  • 5g
  • ManufacturerAK Scientific
  • Product numberZ1845
  • Product descriptionClevidipinebutyrate
  • Packaging10mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA387256
  • Product description3-((Butyryloxy)methyl)5-methyl4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 97%
  • Packaging25mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA387256
  • Product description3-((Butyryloxy)methyl)5-methyl4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 97%
  • Packaging50mg
  • Price$16
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA387256
  • Product description3-((Butyryloxy)methyl)5-methyl4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 97%
  • Packaging100mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA387256
  • Product description3-((Butyryloxy)methyl)5-methyl4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 97%
  • Packaging250mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA387256
  • Product description3-((Butyryloxy)methyl)5-methyl4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 97%
  • Packaging1g
  • Price$118
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA387256
  • Product description3-((Butyryloxy)methyl)5-methyl4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 97%
  • Packaging5g
  • Price$118
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007041
  • Product descriptionCLEVIDIPINE BUTYRATE 95.00%
  • Packaging5MG
  • Price$160.6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007041
  • Product descriptionCLEVIDIPINE BUTYRATE 95.00%
  • Packaging10MG
  • Price$191.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007041
  • Product descriptionCLEVIDIPINE BUTYRATE 95.00%
  • Packaging25MG
  • Price$716.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007041
  • Product descriptionCLEVIDIPINE BUTYRATE 95.00%
  • Packaging250MG
  • Price$1686.3
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1415
  • Product descriptionClevidipineButyrate
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2618
  • Product descriptionClevidipine
  • Packaging25mg
  • Price$69
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2618
  • Product descriptionClevidipine
  • Packaging100mg
  • Price$119
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number2618
  • Product descriptionClevidipine
  • Packaging1g
  • Price$490
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC20480
  • Product descriptionClevidipine
  • Packaging25mg
  • Price$70
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Z1845 Clevidipinebutyrate 10mg $65 2021-12-16 Buy
Ambeed A387256 3-((Butyryloxy)methyl)5-methyl4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 97% 25mg $5 2021-12-16 Buy
Ambeed A387256 3-((Butyryloxy)methyl)5-methyl4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 97% 50mg $16 2021-12-16 Buy
Ambeed A387256 3-((Butyryloxy)methyl)5-methyl4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 97% 100mg $25 2021-12-16 Buy
Ambeed A387256 3-((Butyryloxy)methyl)5-methyl4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 97% 250mg $25 2021-12-16 Buy
Ambeed A387256 3-((Butyryloxy)methyl)5-methyl4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 97% 1g $118 2021-12-16 Buy
Ambeed A387256 3-((Butyryloxy)methyl)5-methyl4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 97% 5g $118 2021-12-16 Buy
American Custom Chemicals Corporation API0007041 CLEVIDIPINE BUTYRATE 95.00% 5MG $160.6 2021-12-16 Buy
American Custom Chemicals Corporation API0007041 CLEVIDIPINE BUTYRATE 95.00% 10MG $191.1 2021-12-16 Buy
American Custom Chemicals Corporation API0007041 CLEVIDIPINE BUTYRATE 95.00% 25MG $716.1 2021-12-16 Buy
American Custom Chemicals Corporation API0007041 CLEVIDIPINE BUTYRATE 95.00% 250MG $1686.3 2021-12-16 Buy
ApexBio Technology B1415 ClevidipineButyrate 10mg $50 2021-12-16 Buy
AvaChem 2618 Clevidipine 25mg $69 2021-12-16 Buy
AvaChem 2618 Clevidipine 100mg $119 2021-12-16 Buy
AvaChem 2618 Clevidipine 1g $490 2021-12-16 Buy
Biosynth Carbosynth FC20480 Clevidipine 25mg $70 2021-12-16 Buy

Properties

Melting point :128-130°C
Boiling point :539.7±50.0 °C(Predicted)
Density :1.289
Flash point :280℃
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Insoluble[in water]
Water Solubility :Insoluble in water
solubility :≥21.4 mg/mL in DMSO; insoluble in H2O; ≥7.45 mg/mL in EtOH with ultrasonic
form :powder to crystal
pka :2.45±0.70(Predicted)
color :White to Light yellow
CAS DataBase Reference :167221-71-8

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P281 Use personal protective equipment as required.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Clevidipine is an ultra-short-acting vasodilator of the dihydropyridine (DHP) class of CCB. It is indicated as an intravenous treatment for the acute management of hypertension when oral therapy is not feasible or not desirable. Clevidipine is the second intravenous CCB to be marketed behind nicardipine for this indication. Both agents are primarily used for urgent treatment of hypertension in cardiac surgical setting, intensive care units, and emergency departments. Other intravenous agents currently on the market for this indication include sodium nitroprusside, nitroglycerin, fenoldopam, hydralazine, esmolol, and labetalol. Clevidipine is a potent, arterial-specific, vasodilator with very little or no effect on the myocardial contractility and venous capacitance. It has a rapid onset and offset of action and a very short plasma half-life, which allows for titration of the drug to achieve precise BP control.
clevidipine is exclusively metabolized in the blood and the tissues. It does not undergo any renal or hepatic metabolism and does not accumulate in the body. Clevidipine is a blocker of L-type calcium channels, which mediate the influx of calcium during depolarization in arterial smooth muscle.

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