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ChemicalBook >> CAS DataBase List >> Cinobufagin

Cinobufagin

Cinobufagin price.
  • $50 - $2295
  • Product name: Cinobufagin
  • CAS: 470-37-1
  • MF: C26H34O6
  • MW: 442.55
  • EINECS:636-927-8
  • MDL Number:MFCD00056825
  • Synonyms:RARECHEM BK HC T302;5b,20(22)-Bufadienolide-3b,16b-diol-14,15b-epoxy 16-acetate;CINOBUFAGIN95%,99%;CINOBUFAGIN(P);TRANS-3-PHENYLPROPENOIC ACID;TRANS-3-BENZENEPROPENOIC ACID;TRANS-CINNAMYLIC ACID;Cinobufagin std.
37 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 002
  • 5mg
  • 10mg
  • 20mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 003
  • 10mM(in 1mL DMSO)
  • 0.5g
  • 1g
  • ManufacturerAHH
  • Product numberMT-49277
  • Product descriptionCinobufagin 98%
  • Packaging0.5g
  • Price$820
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number8074AH
  • Product descriptionCinobufagin
  • Packaging5mg
  • Price$178
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number8074AH
  • Product descriptionCinobufagin
  • Packaging25mg
  • Price$522
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1154
  • Product descriptionCinobufagin
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1154
  • Product descriptionCinobufagin
  • Packaging20mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN98544
  • Product descriptionCinobufagin ≥98%
  • Packaging20mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1135
  • Product descriptionCinobufagin
  • Packaging5mg
  • Price$79
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1135
  • Product descriptionCinobufagin
  • Packaging10mg
  • Price$149
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1135
  • Product descriptionCinobufagin
  • Packaging25mg
  • Price$249
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1135
  • Product descriptionCinobufagin
  • Packaging100mg
  • Price$449
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1135
  • Product descriptionCinobufagin
  • Packaging250mg
  • Price$849
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1135
  • Product descriptionCinobufagin
  • Packaging1g
  • Price$2295
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb593829
  • Product descriptionCinobufagin
  • Packaging20mg
  • Price$340
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb104972
  • Product descriptionCinobufagin >98%,Standard References Grade
  • Packaging20mg
  • Price$569.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb593829
  • Product descriptionCinobufagin
  • Packaging100mg
  • Price$596.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC65673
  • Product descriptionCinobufagin
  • Packaging5mg
  • Price$95
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-49277 Cinobufagin 98% 0.5g $820 2021-12-16 Buy
AK Scientific 8074AH Cinobufagin 5mg $178 2021-12-16 Buy
AK Scientific 8074AH Cinobufagin 25mg $522 2021-12-16 Buy
ApexBio Technology N1154 Cinobufagin 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology N1154 Cinobufagin 20mg $150 2021-12-16 Buy
Arctom CFN98544 Cinobufagin ≥98% 20mg $80 2021-12-16 Buy
AvaChem 1135 Cinobufagin 5mg $79 2021-12-16 Buy
AvaChem 1135 Cinobufagin 10mg $149 2021-12-16 Buy
AvaChem 1135 Cinobufagin 25mg $249 2021-12-16 Buy
AvaChem 1135 Cinobufagin 100mg $449 2021-12-16 Buy
AvaChem 1135 Cinobufagin 250mg $849 2021-12-16 Buy
AvaChem 1135 Cinobufagin 1g $2295 2021-12-16 Buy
Biorbyt Ltd orb593829 Cinobufagin 20mg $340 2021-12-16 Buy
Biorbyt Ltd orb104972 Cinobufagin >98%,Standard References Grade 20mg $569.5 2021-12-16 Buy
Biorbyt Ltd orb593829 Cinobufagin 100mg $596.7 2021-12-16 Buy
Biosynth Carbosynth FC65673 Cinobufagin 5mg $95 2021-12-16 Buy

Properties

Melting point :133 °C(lit.)
Boiling point :300 °C(lit.)
Density :1.261 g/cm3
Flash point :>230 °F
storage temp. :2-8°C
solubility :DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml
form :powder to crystal
pka :15.10±0.70(Predicted)
color :White to Light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H310 Fatal in contact with skin Acute toxicity,dermal Category 1, 2 Danger GHS hazard pictograms P262, P264, P270, P280, P302+P350,P310, P322, P361, P363, P405, P501
H330 Fatal if inhaled Acute toxicity,inhalation Category 1, 2 Danger GHS hazard pictograms P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P302+P350 IF ON SKIN: Gently wash with plenty of soap and water.
P310 Immediately call a POISON CENTER or doctor/physician.

Description

Cinobufagin is a cardiotoxic bufanolide steroid secreted by the Asiatic toad Bufo gargarizans, having similar effects to digitalis and used in traditional Chinese medicine. It has potential antineoplastic activity and now is widely used in clinical practice, especially in anti-liver cancer. It has benn found to suppress cancer cell proliferation and cause apoptosis in cancer cells via a sequence of apoptotic modulators, including mitochondrial Bax and cytosolic chromosome c, and caspases 3, 8, and 9.

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