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ChemicalBook >> CAS DataBase List >> Cimetidine

Cimetidine

Cimetidine price.
  • $5 - $815
  • Product name: Cimetidine
  • CAS: 51481-61-9
  • MF: C10H16N6S
  • MW: 252.34
  • EINECS:257-232-2
  • MDL Number:MFCD00133296
  • Synonyms:SKF-92334;N-CYANO-N'-METHYL-N''-[[2-[(5-METHYL-1H-IMIDAZOL-4-YL)METHYL]THIO]ETHYL]GUANIDINE;Cimetidine (base and/or unspecified salts);Peptol;Tametin;Tratul;Ulcedin;Ulcedine
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  • y0001146
  • 1kg
  • ManufacturerAHH
  • Product numberAPI-1780
  • Product descriptionCimetidine 98%
  • Packaging1000g
  • Price$660
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberH505
  • Product descriptionCimetidine
  • Packaging25g
  • Price$126
  • Updated2021-12-16
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  • ManufacturerAlfa Aesar
  • Product numberJ62825
  • Product descriptionCimetidine, 98+%
  • Packaging5g
  • Price$71.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62825
  • Product descriptionCimetidine, 98+%
  • Packaging10g
  • Price$113.65
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberJ62825
  • Product descriptionCimetidine, 98+%
  • Packaging25g
  • Price$242.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA295450
  • Product descriptionN-Cyano-N'-methyl-N''-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine 98%
  • Packaging100mg
  • Price$5
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA295450
  • Product descriptionN-Cyano-N'-methyl-N''-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine 98%
  • Packaging1g
  • Price$12
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA295450
  • Product descriptionN-Cyano-N'-methyl-N''-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine 98%
  • Packaging5g
  • Price$40
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA295450
  • Product descriptionN-Cyano-N'-methyl-N''-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine 98%
  • Packaging25g
  • Price$109
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA295450
  • Product descriptionN-Cyano-N'-methyl-N''-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine 98%
  • Packaging100g
  • Price$276
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA295450
  • Product descriptionN-Cyano-N'-methyl-N''-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine 98%
  • Packaging500g
  • Price$815
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1557
  • Product descriptionCimetidine
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1557
  • Product descriptionCimetidine
  • Packaging100mg
  • Price$37
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1557
  • Product descriptionCimetidine
  • Packaging1g
  • Price$48
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1557
  • Product descriptionCimetidine
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1557
  • Product descriptionCimetidine
  • Packaging5g
  • Price$80
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1780 Cimetidine 98% 1000g $660 2021-12-16 Buy
AK Scientific H505 Cimetidine 25g $126 2021-12-16 Buy
Alfa Aesar J62825 Cimetidine, 98+% 5g $71.65 2024-03-01 Buy
Alfa Aesar J62825 Cimetidine, 98+% 10g $113.65 2024-03-01 Buy
Alfa Aesar J62825 Cimetidine, 98+% 25g $242.65 2024-03-01 Buy
Ambeed A295450 N-Cyano-N'-methyl-N''-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine 98% 100mg $5 2021-12-16 Buy
Ambeed A295450 N-Cyano-N'-methyl-N''-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine 98% 1g $12 2021-12-16 Buy
Ambeed A295450 N-Cyano-N'-methyl-N''-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine 98% 5g $40 2021-12-16 Buy
Ambeed A295450 N-Cyano-N'-methyl-N''-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine 98% 25g $109 2021-12-16 Buy
Ambeed A295450 N-Cyano-N'-methyl-N''-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine 98% 100g $276 2021-12-16 Buy
Ambeed A295450 N-Cyano-N'-methyl-N''-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine 98% 500g $815 2021-12-16 Buy
ApexBio Technology B1557 Cimetidine 1unit $28 2021-12-16 Buy
ApexBio Technology B1557 Cimetidine 100mg $37 2021-12-16 Buy
ApexBio Technology B1557 Cimetidine 1g $48 2021-12-16 Buy
ApexBio Technology B1557 Cimetidine 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology B1557 Cimetidine 5g $80 2021-12-16 Buy

Properties

Melting point :139-144°C
Boiling point :476.2±55.0 °C(Predicted)
Density :1.2583 (rough estimate)
refractive index :1.5700 (estimate)
storage temp. :2-8°C
solubility :Slightly soluble in water, soluble in ethanol (96 per cent), practically insoluble in methylene chloride. It dissolves in dilute mineral acids.
form :Solid
pka :pKa 6.80 (Uncertain)
color :White to Off-White
Water Solubility :0.5 g/100 mL at 20 ºC
Merck :14,2279
InChIKey :AQIXAKUUQRKLND-UHFFFAOYSA-N
CAS DataBase Reference :51481-61-9(CAS DataBase Reference)
NIST Chemistry Reference :Cimetidine(51481-61-9)
IARC :3 (Vol. 50) 1990
EPA Substance Registry System :Guanidine, N-cyano-N'-methyl-N''-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]- (51481-61-9)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H303 May be harmfulif swallowed Acute toxicity,oral Category 5 P312
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.

Description

Cimetidine (brand name: Tagamet) is a kind of histamine H2 receptor antagonist being capable of inhibiting the production of stomach acid, which reduces the gastric volume and acidity. It is mainly used for the treatment of heartburn and peptic ulcers. There are also evidences that it can be used for the treatment of common warts, chronic calcific tendinitis of the shoulder, and even colorectal cancer. It is capable of not only inhibiting the gastric acid secretion, as well as pepsin and gastrins output, but also inhibiting the activity of cytochrome P450. It reduces the gastric acid secretion through binding to the H2 receptor locating on the basolateral membrane of the gastric parietal cell, and further blocking histamine effect.

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