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ChemicalBook >> CAS DataBase List >> Apixaban

Apixaban

Apixaban price.
  • $5 - $3036
  • Product name: Apixaban
  • CAS: 503612-47-3
  • MF: C25H25N5O4
  • MW: 459.5
  • EINECS:639-684-6
  • MDL Number:MFCD11977295
  • Synonyms:Apixaban;Apixaban, BMS 562247-01;BMS 562247-01;1-(4-Methoxy-phenyl)-7-oxo-6-[4-(2-oxo-piperidin-1-yl)-phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid aMide;1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4, 5-dihydropyrazolo[3,4-c]pyridine-3-carboxaMide;Nilotinib and its interMediate;Apixaban ,ELIQUIS;1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide Apixaban
43 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemcia Scientific
  • Chemenu
  • ChemScene
  • Chemtos
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1mg
  • 5mg
  • 20mg
  • 200mg
  • 500mg
  • 1g
  • 2g
  • 10mM(in 1mL DMSO)
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 5g
  • 25g
  • ManufacturerAK Scientific
  • Product numberJ98380
  • Product descriptionApixaban
  • Packaging1g
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA334174
  • Product description1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide 98+%
  • Packaging10mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA334174
  • Product description1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide 98+%
  • Packaging50mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA334174
  • Product description1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide 98+%
  • Packaging100mg
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA334174
  • Product description1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide 98+%
  • Packaging250mg
  • Price$19
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA334174
  • Product description1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide 98+%
  • Packaging1g
  • Price$46
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA334174
  • Product description1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide 98+%
  • Packaging5g
  • Price$165
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA334174
  • Product description1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide 98+%
  • Packaging25g
  • Price$565
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4341
  • Product descriptionApixaban
  • Packaging10mM(in 1mL DMSO)
  • Price$83
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4341
  • Product descriptionApixaban
  • Packaging10mg
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4341
  • Product descriptionApixaban
  • Packaging50mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4341
  • Product descriptionApixaban
  • Packaging200mg
  • Price$375
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60351
  • Product descriptionApixaban ≥98%
  • Packaging20mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1754
  • Product descriptionApixaban-BMS562247-01 98%
  • Packaging10mg
  • Price$104.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180767
  • Product descriptionApixaban (BMS 562247-01) >98%
  • Packaging100mg
  • Price$606.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180767
  • Product descriptionApixaban (BMS 562247-01) >98%
  • Packaging250mg
  • Price$765
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J98380 Apixaban 1g $120 2021-12-16 Buy
Ambeed A334174 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide 98+% 10mg $5 2021-12-16 Buy
Ambeed A334174 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide 98+% 50mg $8 2021-12-16 Buy
Ambeed A334174 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide 98+% 100mg $10 2021-12-16 Buy
Ambeed A334174 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide 98+% 250mg $19 2021-12-16 Buy
Ambeed A334174 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide 98+% 1g $46 2021-12-16 Buy
Ambeed A334174 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide 98+% 5g $165 2021-12-16 Buy
Ambeed A334174 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide 98+% 25g $565 2021-12-16 Buy
ApexBio Technology A4341 Apixaban 10mM(in 1mL DMSO) $83 2021-12-16 Buy
ApexBio Technology A4341 Apixaban 10mg $116 2021-12-16 Buy
ApexBio Technology A4341 Apixaban 50mg $189 2021-12-16 Buy
ApexBio Technology A4341 Apixaban 200mg $375 2021-12-16 Buy
Arctom CFN60351 Apixaban ≥98% 20mg $70 2021-12-16 Buy
Axon Medchem Axon1754 Apixaban-BMS562247-01 98% 10mg $104.5 2021-12-16 Buy
Biorbyt Ltd orb180767 Apixaban (BMS 562247-01) >98% 100mg $606.9 2021-12-16 Buy
Biorbyt Ltd orb180767 Apixaban (BMS 562247-01) >98% 250mg $765 2021-12-16 Buy

Properties

Melting point :235-238°C
Boiling point :770.5±60.0 °C(Predicted)
Density :1.42
storage temp. :Refrigerator
solubility :DMSO (Slightly, Heated), Methanol (Slightly)
pka :15.01±0.20(Predicted)
form :Solid
color :White to Off-White
InChIKey :QNZCBYKSOIHPEH-UHFFFAOYSA-N
SMILES :C1(=O)N(C2=CC=C(N3CCCCC3=O)C=C2)CCC2C(C(N)=O)=NN(C3=CC=C(OC)C=C3)C1=2

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Apixaban (Tradename: Eliquis) is a kind of orally-taken, direct, and highly selective factor Xa inhibitor, which can be used as the anticoagulant. It is used for the treatment of venous thromboembolic events, deep vein thrombosis and pulmonary embolism. The anticoagulant effect of apixaban is mediated by directly inhibiting the free and clot-bound factor Xa, which catalyzed the conversion of prothrombin to thrombin. It has no direct effect on platelet aggregation.
Factor Xa is an integral enzyme of the coagulation cascade that catalyzes the formation of thrombin. Apixaban is an orally available, selective inhibitor of both free and prothrombinase-bound factor Xa (Ki = 0.8 nM). Apixaban is an effective anticoagulant in both preclinical and clinical models of venous and arterial thrombosis.

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