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ChemicalBook >> CAS DataBase List >> Apafant

Apafant

Apafant price.
  • $50 - $1732.5
  • Product name: Apafant
  • CAS: 105219-56-5
  • MF: C22H22ClN5O2S
  • MW: 455.96
  • EINECS:
  • MDL Number:MFCD00865271
  • Synonyms:4-[3-[4-(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-oxopropyl]-morpholine;WEB 208;WEB 2086BS;4-[3-[4-(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-α][1,4]diazepin-2-yl]-1-oxopropyl]-morpholine;3-[4-(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-(4-morpholinyl)-1-propanone;4-(2-Chlorophenyl)-9-methyl-2-(3-morpholino-3-oxopropyl)-6H-thieno[3,2- f] [1,2,4]triazolo[4,3-a][1,4]diazepine;4-[3-[4[(2-CHLOROPHENYL)-9-METHYL-6H-THIENO[3,2-F][1,2,4]TRIAZOLO[4,3-A]DIAZEPIN-2-YL]-1-OXOPROPYL]]MORPHOLINE;WEB 2086
15 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 1
  • 10
  • 1mg
  • 2mg
  • 5mg
  • 10MG
  • 25mg
  • 50mg
  • ManufacturerAK Scientific
  • Product number1890BA
  • Product descriptionApafant
  • Packaging1mg
  • Price$154
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0015803
  • Product description4-[3-[4-(2-CHLOROPHENYL)-9-METHYL-6H-THIENO[3,2-F][1,2,4]TRIAZOLO[4,3-A][1,4]DIAZEPIN-2-YL]-1-OXOPROPYL]-MORPHOLINE 95.00%
  • Packaging10MG
  • Price$1732.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0015803
  • Product description4-[3-[4-(2-CHLOROPHENYL)-9-METHYL-6H-THIENO[3,2-F][1,2,4]TRIAZOLO[4,3-A][1,4]DIAZEPIN-2-YL]-1-OXOPROPYL]-MORPHOLINE 95.00%
  • Packaging1MG
  • Price$154.35
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7024
  • Product descriptionWEB2086
  • Packaging5mg
  • Price$378
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA17951
  • Product descriptionApafant
  • Packaging50mg
  • Price$612.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA17951
  • Product descriptionApafant
  • Packaging10mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14532
  • Product descriptionApafant ≥98%
  • Packaging1mg
  • Price$50
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14532
  • Product descriptionApafant ≥98%
  • Packaging5mg
  • Price$122
  • Updated2024-03-01
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number6903
  • Product descriptionApafant
  • Packaging5mg
  • Price$875
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0238
  • Product descriptionWEB2086 ≥98% (HPLC)
  • Packaging25mg
  • Price$631
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0238
  • Product descriptionWEB2086 ≥98% (HPLC)
  • Packaging5mg
  • Price$158
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number2339
  • Product descriptionWEB2086 ≥99%(HPLC)
  • Packaging1
  • Price$127
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number2339
  • Product descriptionWEB2086 ≥99%(HPLC)
  • Packaging10
  • Price$271
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberA726100
  • Product descriptionApafant
  • Packaging2mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number257100
  • Product descriptionWEB 2086
  • Packaging1mg
  • Price$366
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1890BA Apafant 1mg $154 2021-12-16 Buy
American Custom Chemicals Corporation API0015803 4-[3-[4-(2-CHLOROPHENYL)-9-METHYL-6H-THIENO[3,2-F][1,2,4]TRIAZOLO[4,3-A][1,4]DIAZEPIN-2-YL]-1-OXOPROPYL]-MORPHOLINE 95.00% 10MG $1732.5 2021-12-16 Buy
American Custom Chemicals Corporation API0015803 4-[3-[4-(2-CHLOROPHENYL)-9-METHYL-6H-THIENO[3,2-F][1,2,4]TRIAZOLO[4,3-A][1,4]DIAZEPIN-2-YL]-1-OXOPROPYL]-MORPHOLINE 95.00% 1MG $154.35 2021-12-16 Buy
ApexBio Technology B7024 WEB2086 5mg $378 2021-12-16 Buy
Biosynth Carbosynth FA17951 Apafant 50mg $612.5 2021-12-16 Buy
Biosynth Carbosynth FA17951 Apafant 10mg $400 2021-12-16 Buy
Cayman Chemical 14532 Apafant ≥98% 1mg $50 2024-03-01 Buy
Cayman Chemical 14532 Apafant ≥98% 5mg $122 2024-03-01 Buy
Medical Isotopes, Inc. 6903 Apafant 5mg $875 2021-12-16 Buy
Sigma-Aldrich SML0238 WEB2086 ≥98% (HPLC) 25mg $631 2024-03-01 Buy
Sigma-Aldrich SML0238 WEB2086 ≥98% (HPLC) 5mg $158 2024-03-01 Buy
Tocris 2339 WEB2086 ≥99%(HPLC) 1 $127 2021-12-16 Buy
Tocris 2339 WEB2086 ≥99%(HPLC) 10 $271 2021-12-16 Buy
TRC A726100 Apafant 2mg $65 2021-12-16 Buy
Usbiological 257100 WEB 2086 1mg $366 2021-12-16 Buy

Properties

Melting point :186-188°C
Boiling point :720.2±70.0 °C(Predicted)
Density :1.48
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL (clear solution)
pka :2.36±0.40(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P281 Use personal protective equipment as required.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Platelet-activating factor (PAF) is a biologically active phospholipid that activates platelets, polymorphonuclear leukocytes, monocytes, and macrophages. PAF also increases vascular permeability, decreases cardiac output, induces hypotension, stimulates uterine contraction, and has been implicated in pathological processes, such as inflammation and allergy. Apafant is a water soluble, selective PAF receptor antagonist that inhibits PAF binding to human PAF receptors with a Ki value of 9.9 nM. Apafant displays anti-inflammatory, antiangiogenic, and anticancer activity.

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