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ChemicalBook >> CAS DataBase List >> (S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER

(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER

(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER price.
  • $498.06 - $1595
  • Product name: (S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER
  • CAS: 7101-51-1
  • MF: C10H13NO4
  • MW: 211.21
  • EINECS:
  • MDL Number:MFCD00870911
  • Synonyms:(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER;levodopa methyl ester;DOPA-METHYLESTER;L-DOPA Methyl Ester;(S)-2-AMino-3-(3,4-dihydroxy-phenyl)-propionic acid Methyl ester hydrochloride;L-Tyrosine, 3-hydroxy-, Methyl ester;Methyl 3-hydroxy-L-tyrosinate;methyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate
6 prices
Selected condition：
Brand
  • Alichem
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Chemenu
  • Crysdot
Package
  • 5MG
  • 1g
  • 5g
  • ManufacturerAlichem
  • Product number7101511
  • Product description(S)-Methyl2-amino-3-(3,4-dihydroxyphenyl)propanoate
  • Packaging5g
  • Price$805.98
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCCH0004417
  • Product description(S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER 95.00%
  • Packaging5MG
  • Price$498.06
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR955473
  • Product description3-Hydroxy-L-tyrosinemethylester 96%
  • Packaging1g
  • Price$508
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR955473
  • Product description3-Hydroxy-L-tyrosinemethylester 96%
  • Packaging5g
  • Price$1595
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM283194
  • Product description(S)-Methyl2-amino-3-(3,4-dihydroxyphenyl)propanoate 95%
  • Packaging5g
  • Price$746
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD21003806
  • Product description(S)-Methyl2-amino-3-(3,4-dihydroxyphenyl)propanoate 95+%
  • Packaging5g
  • Price$790
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alichem 7101511 (S)-Methyl2-amino-3-(3,4-dihydroxyphenyl)propanoate 5g $805.98 2021-12-16 Buy
American Custom Chemicals Corporation CCH0004417 (S)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-PROPIONIC ACID METHYL ESTER 95.00% 5MG $498.06 2021-12-16 Buy
Apolloscientific OR955473 3-Hydroxy-L-tyrosinemethylester 96% 1g $508 2021-12-16 Buy
Apolloscientific OR955473 3-Hydroxy-L-tyrosinemethylester 96% 5g $1595 2021-12-16 Buy
Chemenu CM283194 (S)-Methyl2-amino-3-(3,4-dihydroxyphenyl)propanoate 95% 5g $746 2021-12-16 Buy
Crysdot CD21003806 (S)-Methyl2-amino-3-(3,4-dihydroxyphenyl)propanoate 95+% 5g $790 2021-12-16 Buy

Properties

Boiling point :350.89°C (rough estimate)
Density :1.2545 (rough estimate)
refractive index :1.5150 (estimate)
storage temp. :2-8°C
form :solid
pka :9.67±0.20(Predicted)
color :White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

Description

CHF-1301 was launched as an injection in Italy for the treatment of patients with Parkinson's disease, particularly those with complications in their clinical responses. CHF-1301 is the methyl ester of L-Dopa (levodopa), the immediate precursor of dopamine. Thus, this prodrug is more soluble in water at physiological pH, better absorbed and slowly transformed into levodopa in vivo; it consequently improves the duration of action and prevents the rapid fluctuations in response or involontary movements (dyskinesia) observed during chronic treatment with levodopa. In patients with a delayed effect of levodopa (on-phenomenon) or a severe resistance to L-Dopa (off-phenomenon), CHF- 1301 significantly improves the onset and the stability of the'response.

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