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ChemicalBook >> CAS DataBase List >> L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoaMino]-, (Hydrochloride) (1:2)

L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoaMino]-, (Hydrochloride) (1:2)

L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoaMino]-, (Hydrochloride) (1:2) price.
  • $30 - $3580.2
  • Product name: L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoaMino]-, (Hydrochloride) (1:2)
  • CAS: 685898-44-6
  • MF: C13H19Cl3N2O3
  • MW: 357.66
  • EINECS:
  • MDL Number:MFCD11840749
  • Synonyms:L-Phenylalanine, 4-[bis(2-chloroethyl)oxidoaMino]-, (Hydrochloride) (1:2);PX-478 dihydrochloride;PX478 2HCl;4-[bis(2-chloroethyl)oxidoamino]-L-phenylalanine,hydrochloride (1:2);PX-478 HCl;Phenylalanine, 4-[bis(2-chloroethyl)oxidoaMino]-, (Hydrochloride) (1:2);4-[Bis(2-chloroethyl)oxidoamino]-L-phenylalanine dihydrochloride;(S)-4-(2-Amino-2-carboxyethyl)-N,N-bis(2-chloroethyl)aniline oxide dihydrochloride
25 prices
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Brand
  • Activate Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1000mg
  • ManufacturerActivate Scientific
  • Product numberAS111870
  • Product descriptionPX-478 2HCl 96%
  • Packaging25mg
  • Price$475
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA812611
  • Product description(S)-4-(2-Amino-2-carboxyethyl)-N,N-bis(2-chloroethyl)cyclohexa-1,3-dienamineoxidedihydrochloride 98+%
  • Packaging5mg
  • Price$173
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA812611
  • Product description(S)-4-(2-Amino-2-carboxyethyl)-N,N-bis(2-chloroethyl)cyclohexa-1,3-dienamineoxidedihydrochloride 98+%
  • Packaging10mg
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA812611
  • Product description(S)-4-(2-Amino-2-carboxyethyl)-N,N-bis(2-chloroethyl)cyclohexa-1,3-dienamineoxidedihydrochloride 98+%
  • Packaging50mg
  • Price$381
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005290
  • Product descriptionPX-478 95.00%
  • Packaging5MG
  • Price$505.81
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6004
  • Product descriptionPX-4782HCl
  • Packaging5mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6004
  • Product descriptionPX-4782HCl
  • Packaging10mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6004
  • Product descriptionPX-4782HCl
  • Packaging50mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181308
  • Product descriptionPX-478 2HCL >98%
  • Packaging100mg
  • Price$986
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181308
  • Product descriptionPX-478 2HCL >98%
  • Packaging250mg
  • Price$1802
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181308
  • Product descriptionPX-478 2HCL >98%
  • Packaging1000mg
  • Price$3580.2
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10005189
  • Product descriptionPX-478 ≥95%
  • Packaging1mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10005189
  • Product descriptionPX-478 ≥95%
  • Packaging5mg
  • Price$66
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10005189
  • Product descriptionPX-478 ≥95%
  • Packaging10mg
  • Price$117
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10005189
  • Product descriptionPX-478 ≥95%
  • Packaging25mg
  • Price$259
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10005189
  • Product descriptionPX-478 ≥95%
  • Packaging50mg
  • Price$387
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Activate Scientific AS111870 PX-478 2HCl 96% 25mg $475 2021-12-16 Buy
Ambeed A812611 (S)-4-(2-Amino-2-carboxyethyl)-N,N-bis(2-chloroethyl)cyclohexa-1,3-dienamineoxidedihydrochloride 98+% 5mg $173 2021-12-16 Buy
Ambeed A812611 (S)-4-(2-Amino-2-carboxyethyl)-N,N-bis(2-chloroethyl)cyclohexa-1,3-dienamineoxidedihydrochloride 98+% 10mg $225 2021-12-16 Buy
Ambeed A812611 (S)-4-(2-Amino-2-carboxyethyl)-N,N-bis(2-chloroethyl)cyclohexa-1,3-dienamineoxidedihydrochloride 98+% 50mg $381 2021-12-16 Buy
American Custom Chemicals Corporation API0005290 PX-478 95.00% 5MG $505.81 2021-12-16 Buy
ApexBio Technology B6004 PX-4782HCl 5mg $80 2021-12-16 Buy
ApexBio Technology B6004 PX-4782HCl 10mg $140 2021-12-16 Buy
ApexBio Technology B6004 PX-4782HCl 50mg $350 2021-12-16 Buy
Biorbyt Ltd orb181308 PX-478 2HCL >98% 100mg $986 2021-12-16 Buy
Biorbyt Ltd orb181308 PX-478 2HCL >98% 250mg $1802 2021-12-16 Buy
Biorbyt Ltd orb181308 PX-478 2HCL >98% 1000mg $3580.2 2021-12-16 Buy
Cayman Chemical 10005189 PX-478 ≥95% 1mg $30 2021-12-16 Buy
Cayman Chemical 10005189 PX-478 ≥95% 5mg $66 2024-03-01 Buy
Cayman Chemical 10005189 PX-478 ≥95% 10mg $117 2024-03-01 Buy
Cayman Chemical 10005189 PX-478 ≥95% 25mg $259 2024-03-01 Buy
Cayman Chemical 10005189 PX-478 ≥95% 50mg $387 2024-03-01 Buy

Properties

storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :≥19.7 mg/mL in DMSO; ≥50 mg/mL in H2O; ≥8.42 mg/mL in EtOH
form :Powder
color :Off-white to yellow
CAS DataBase Reference :685898-44-6

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PX 478 is a HIF-1α inhibitor that may be used in cancer therapy for treatment of solid tumors. PX478 has also been shown to suppress high-fat-diet (HFD)-induced HIFα activation in adipose tissue in mice and therefore may be used to ameliorate adipose tissue dysfunction.

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