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ChemicalBook >> CAS DataBase List >> 2,4-Pyridinedicarboxylic acid

2,4-Pyridinedicarboxylic acid

2,4-Pyridinedicarboxylic acid price.
  • $8 - $1079
  • Product name: 2,4-Pyridinedicarboxylic acid
  • CAS: 499-80-9
  • MF: C7H5NO4
  • MW: 167.12
  • EINECS:207-892-2
  • MDL Number:MFCD00006296
  • Synonyms:RARECHEM AL BO 0286;PYRIDINE-2,4-DICARBOXYLIC ACID;LUTIDINIC ACID;2,4-LUTIDINIC ACID;2,4-PYRIDINEDICARBOXYLIC ACID;2,4-Pyridinedicarboxylic acid hydrate;2,4-PyridinecarboxylicAcid;2,4-Pyridinedicarboxylic acid hydrate, 99+%
43 prices
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Brand
  • AHH
  • AK Scientific
  • Alfa Aesar
  • Alichem
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • SynQuest Laboratories
  • TCI Chemical
  • TRC
Package
  • 1g
  • 2.5G
  • 5g
  • 10mM(in 1mL DMSO)
  • 10g
  • 25g
  • 50g
  • 100g
  • 500g
  • 1kg
  • ManufacturerAHH
  • Product numberMT-21915
  • Product descriptionPyridine-2,4-dicarboxylicacid 99%
  • Packaging100g
  • Price$245
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberZ6086
  • Product description2,4-Pyridinedicarboxylic Acid
  • Packaging5g
  • Price$91
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA14409
  • Product descriptionPyridine-2,4-dicarboxylic acid, 98%, may cont. up to ca 10% water
  • Packaging5g
  • Price$56.9
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA14409
  • Product descriptionPyridine-2,4-dicarboxylic acid, 98%, may cont. up to ca 10% water
  • Packaging25g
  • Price$203
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA14409
  • Product descriptionPyridine-2,4-dicarboxylic acid, 98%, may cont. up to ca 10% water
  • Packaging100g
  • Price$696
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number499809
  • Product descriptionPyridine-2,4-dicarboxylicacid
  • Packaging1kg
  • Price$599
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA144466
  • Product descriptionPyridine-2,4-dicarboxylicacid 99%
  • Packaging1g
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA144466
  • Product descriptionPyridine-2,4-dicarboxylicacid 99%
  • Packaging5g
  • Price$23
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA144466
  • Product descriptionPyridine-2,4-dicarboxylicacid 99%
  • Packaging10g
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA144466
  • Product descriptionPyridine-2,4-dicarboxylicacid 99%
  • Packaging25g
  • Price$98
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA144466
  • Product descriptionPyridine-2,4-dicarboxylicacid 99%
  • Packaging100g
  • Price$288
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA144466
  • Product descriptionPyridine-2,4-dicarboxylicacid 99%
  • Packaging500g
  • Price$1079
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0019631
  • Product description2,4-PYRIDINEDICARBOXYLIC ACID 95.00%
  • Packaging1G
  • Price$597.87
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0019631
  • Product description2,4-PYRIDINEDICARBOXYLIC ACID 95.00%
  • Packaging2.5G
  • Price$746.88
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0019631
  • Product description2,4-PYRIDINEDICARBOXYLIC ACID 95.00%
  • Packaging5G
  • Price$808.96
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5972
  • Product description2,4-Pyridinedicarboxylic Acid
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-21915 Pyridine-2,4-dicarboxylicacid 99% 100g $245 2021-12-16 Buy
AK Scientific Z6086 2,4-Pyridinedicarboxylic Acid 5g $91 2021-12-16 Buy
Alfa Aesar A14409 Pyridine-2,4-dicarboxylic acid, 98%, may cont. up to ca 10% water 5g $56.9 2021-12-16 Buy
Alfa Aesar A14409 Pyridine-2,4-dicarboxylic acid, 98%, may cont. up to ca 10% water 25g $203 2021-12-16 Buy
Alfa Aesar A14409 Pyridine-2,4-dicarboxylic acid, 98%, may cont. up to ca 10% water 100g $696 2021-12-16 Buy
Alichem 499809 Pyridine-2,4-dicarboxylicacid 1kg $599 2021-12-16 Buy
Ambeed A144466 Pyridine-2,4-dicarboxylicacid 99% 1g $8 2021-12-16 Buy
Ambeed A144466 Pyridine-2,4-dicarboxylicacid 99% 5g $23 2021-12-16 Buy
Ambeed A144466 Pyridine-2,4-dicarboxylicacid 99% 10g $45 2021-12-16 Buy
Ambeed A144466 Pyridine-2,4-dicarboxylicacid 99% 25g $98 2021-12-16 Buy
Ambeed A144466 Pyridine-2,4-dicarboxylicacid 99% 100g $288 2021-12-16 Buy
Ambeed A144466 Pyridine-2,4-dicarboxylicacid 99% 500g $1079 2021-12-16 Buy
American Custom Chemicals Corporation CHM0019631 2,4-PYRIDINEDICARBOXYLIC ACID 95.00% 1G $597.87 2021-12-16 Buy
American Custom Chemicals Corporation CHM0019631 2,4-PYRIDINEDICARBOXYLIC ACID 95.00% 2.5G $746.88 2021-12-16 Buy
American Custom Chemicals Corporation CHM0019631 2,4-PYRIDINEDICARBOXYLIC ACID 95.00% 5G $808.96 2021-12-16 Buy
ApexBio Technology B5972 2,4-Pyridinedicarboxylic Acid 10mM(in 1mL DMSO) $50 2021-12-16 Buy

Properties

Melting point :243-246 °C
Boiling point :295.67°C (rough estimate)
Density :1.5216 (rough estimate)
vapor pressure :0.001Pa at 25℃
refractive index :1.6280 (estimate)
storage temp. :Store below +30°C.
solubility :2.49g/l
form :Crystalline Powder
pka :2.15(at 25℃)
color :White to almost white
Water Solubility :Soluble in water at 20°C 4.5 g/L.
λmax :258nm(MeOH aq.)(lit.)
BRN :131631
LogP :0.57
CAS DataBase Reference :499-80-9(CAS DataBase Reference)
EPA Substance Registry System :2,4-Pyridinedicarboxylic acid (499-80-9)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

2,4-Pyridinedicarboxylic Acid (2,4-PDCA) is a compound that structurally mimics 2-oxoglutarate (2-OG, also known as α-ketoglutarate) and chelates zinc, thus affecting a range of enzymes. As a 2-OG mimic, it blocks the activity of 2-OG oxygenases, which include certain lysine demethylases and a variety of hydroxylases (e.g., prolyl, collagen, lysyl). 2,4-PDCA inhibits several Jumonji domain-containing lysine demethylases when used at low micromolar concentrations. Through its effects on hydroxylases, including prolyl hydroxlase 1 (IC50 = 1.5 μM), 2,4-PDCA modulates hypoxia-inducible factor turnover, collagen synthesis, and plant cell wall formation. It can inhibit zinc-dependent enzymes, like metallo-β-lactamase. 2,4-PDCA also affects and is translocated by organic anion transporters.

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