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ChemicalBook >> CAS DataBase List >> 4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine

4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine

4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine price.
  • $10 - $2152.5
  • Product name: 4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine
  • CAS: 479633-63-1
  • MF: C13H10ClN3O2S
  • MW: 307.76
  • EINECS:811-000-2
  • MDL Number:MFCD09907939
  • Synonyms:Tofacitinib Impurity R;4-Chloro-7-(p-tolylsulfonyl)pyrrolo[2,3-d]pyrimidine;4-CHLORO-7-[(4-METHYLPHENYL)SULFONYL]-7H-PYRROLO[2,3-D]PYRIMIDINE;4-CHLORO-7-TOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE;4-Chloro-7-tosyl-7H-pyrro...;4-Chloro-7-[(4-methylbenzene)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine;4-Chloro-7-p-toluenesulphonyl-7H-pyrrolo[2,3-d]pyrimidine;7H-Pyrrolo[2,3-D]pyriMidine,4-chloro-7-[(4-Methylphenyl)sulfonyl]-
23 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Biosynth Carbosynth
  • Chemenu
  • Chem-Impex
  • Crysdot
  • Matrix Scientific
  • Sigma-Aldrich
  • SynQuest Laboratories
  • TCI Chemical
Package
  • 1g
  • 5g
  • 10g
  • 25g
  • 50g
  • 100g
  • 250g
  • ManufacturerAK Scientific
  • Product numberAMTH013
  • Product description4-Chloro-7-(toluene-4-sulfonyl)-7H-pyrrolo[2,3-d]pyrimidine
  • Packaging5g
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberAMTH013
  • Product description4-Chloro-7-(toluene-4-sulfonyl)-7H-pyrrolo[2,3-d]pyrimidine
  • Packaging1g
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0027895
  • Product description4-CHLORO-7-TOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE 95.00%
  • Packaging1G
  • Price$722.8
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR317249
  • Product description4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine
  • Packaging1g
  • Price$109
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR317249
  • Product description4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine
  • Packaging5g
  • Price$327
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR317249
  • Product description4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine
  • Packaging10g
  • Price$573
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC10607
  • Product description4-Chloro-7-p-toluenesulphonyl-7H-pyrrolo[2,3-d]pyrimidine
  • Packaging250g
  • Price$2152.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC10607
  • Product description4-Chloro-7-p-toluenesulphonyl-7H-pyrrolo[2,3-d]pyrimidine
  • Packaging100g
  • Price$1155
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC10607
  • Product description4-Chloro-7-p-toluenesulphonyl-7H-pyrrolo[2,3-d]pyrimidine
  • Packaging50g
  • Price$735
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC10607
  • Product description4-Chloro-7-p-toluenesulphonyl-7H-pyrrolo[2,3-d]pyrimidine
  • Packaging25g
  • Price$472.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC10607
  • Product description4-Chloro-7-p-toluenesulphonyl-7H-pyrrolo[2,3-d]pyrimidine
  • Packaging10g
  • Price$262.5
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM103622
  • Product description4-chloro-7-(4-methylbenzenesulfonyl)-7H-pyrrolo[2,3-d]pyrimidine 95%+
  • Packaging100g
  • Price$152
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM103622
  • Product description4-chloro-7-(4-methylbenzenesulfonyl)-7H-pyrrolo[2,3-d]pyrimidine 95%+
  • Packaging25g
  • Price$51
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number44813
  • Product description4-Chloro-7-(p-toluenesulfonyl)-7H-pyrrolo[2,3-d]pyrimidine,≥96%(HPLC) ≥96%(HPLC)
  • Packaging1G
  • Price$62.4
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11118019
  • Product description4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine 98%
  • Packaging100g
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number058631
  • Product description4-Chloro-7-[(4-methylbenzene)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine >95%
  • Packaging1g
  • Price$10
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific AMTH013 4-Chloro-7-(toluene-4-sulfonyl)-7H-pyrrolo[2,3-d]pyrimidine 5g $15 2021-12-16 Buy
AK Scientific AMTH013 4-Chloro-7-(toluene-4-sulfonyl)-7H-pyrrolo[2,3-d]pyrimidine 1g $10 2021-12-16 Buy
American Custom Chemicals Corporation API0027895 4-CHLORO-7-TOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE 95.00% 1G $722.8 2021-12-16 Buy
Apolloscientific OR317249 4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine 1g $109 2021-12-16 Buy
Apolloscientific OR317249 4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine 5g $327 2021-12-16 Buy
Apolloscientific OR317249 4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine 10g $573 2021-12-16 Buy
Biosynth Carbosynth FC10607 4-Chloro-7-p-toluenesulphonyl-7H-pyrrolo[2,3-d]pyrimidine 250g $2152.5 2021-12-16 Buy
Biosynth Carbosynth FC10607 4-Chloro-7-p-toluenesulphonyl-7H-pyrrolo[2,3-d]pyrimidine 100g $1155 2021-12-16 Buy
Biosynth Carbosynth FC10607 4-Chloro-7-p-toluenesulphonyl-7H-pyrrolo[2,3-d]pyrimidine 50g $735 2021-12-16 Buy
Biosynth Carbosynth FC10607 4-Chloro-7-p-toluenesulphonyl-7H-pyrrolo[2,3-d]pyrimidine 25g $472.5 2021-12-16 Buy
Biosynth Carbosynth FC10607 4-Chloro-7-p-toluenesulphonyl-7H-pyrrolo[2,3-d]pyrimidine 10g $262.5 2021-12-16 Buy
Chemenu CM103622 4-chloro-7-(4-methylbenzenesulfonyl)-7H-pyrrolo[2,3-d]pyrimidine 95%+ 100g $152 2021-12-16 Buy
Chemenu CM103622 4-chloro-7-(4-methylbenzenesulfonyl)-7H-pyrrolo[2,3-d]pyrimidine 95%+ 25g $51 2021-12-16 Buy
Chem-Impex 44813 4-Chloro-7-(p-toluenesulfonyl)-7H-pyrrolo[2,3-d]pyrimidine,≥96%(HPLC) ≥96%(HPLC) 1G $62.4 2021-12-16 Buy
Crysdot CD11118019 4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine 98% 100g $135 2021-12-16 Buy
Matrix Scientific 058631 4-Chloro-7-[(4-methylbenzene)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine >95% 1g $10 2021-12-16 Buy

Properties

Melting point :145.0 to 149.0 °C
Boiling point :505.3±60.0 °C(Predicted)
Density :1.49
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :Chloroform (Slightly), DMSO (Slightly)
form :powder to crystal
pka :1.73±0.30(Predicted)
color :White to Orange to Green
InChI :InChI=1S/C13H10ClN3O2S/c1-9-2-4-10(5-3-9)20(18,19)17-7-6-11-12(14)15-8-16-13(11)17/h2-8H,1H3
InChIKey :BTOJSYRZQZOMOK-UHFFFAOYSA-N
SMILES :C1=NC(Cl)=C2C=CN(S(C3=CC=C(C)C=C3)(=O)=O)C2=N1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine is a reagent in the synthesis of (+)-tofacitinib, a selective Janus kinase 3 inhibitor (JAK3) and an immunosuppressant drug.

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