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ChemicalBook >> CAS DataBase List >> 4-HYDROXYISOLEUCINE

4-HYDROXYISOLEUCINE

4-HYDROXYISOLEUCINE price.
  • $68 - $1455
  • Product name: 4-HYDROXYISOLEUCINE
  • CAS: 55399-93-4
  • MF: C6H13NO3
  • MW: 147.17
  • EINECS:2017-001-1
  • MDL Number:MFCD07357252
  • Synonyms:4-HYDROXYISOLEUCINE; 4-HYDROXY-L-ISOLEUCINE;HIL;HYDROXYISOLEUCINE, 4-;2-AMINO-2,3,5-TRIDEOXY-3-METHYL-D-XYLONIC ACID;(2S,3R,4S)-4-HYDROXYISOLEUCINE MAJOR ISOMER AND (2R,3R,4S)-4-HYDROXYISOLEUCINE MINOR ISOMER;[DISCONTINUED] Replaced by KIT-00008502-0HK;HYDROXYISOLEUCINE, 4-(FG);(2S,3R,4S)-2-Amino-4-hydroxy-3-methylpentanoic acid
15 prices
Selected condition：
Brand
  • AK Scientific
  • Arctom
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • SynQuest Laboratories
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 20mg
  • 25mg
  • 50mg
  • 1g
  • 5g
  • ManufacturerAK Scientific
  • Product number4577CQ
  • Product descriptionHydroxyisoleucine
  • Packaging1mg
  • Price$174
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSY232484
  • Product description4-Hydroxyisoleucine ≥98%
  • Packaging10mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11812
  • Product description4-Hydroxyisoleucine
  • Packaging1mg
  • Price$68
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11812
  • Product description4-Hydroxyisoleucine
  • Packaging5mg
  • Price$302
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11812
  • Product description4-Hydroxyisoleucine
  • Packaging10mg
  • Price$535
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11812
  • Product description4-Hydroxyisoleucine
  • Packaging25mg
  • Price$1169
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM133299
  • Product description(2S,3R,4S)-2-amino-4-hydroxy-3-methylpentanoicacid 95%
  • Packaging1g
  • Price$302
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM133299
  • Product description(2S,3R,4S)-2-amino-4-hydroxy-3-methylpentanoicacid 95%
  • Packaging5g
  • Price$1200
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD21006049
  • Product description(2S,3R,4S)-2-Amino-4-hydroxy-3-methylpentanoicacid 95+%
  • Packaging1g
  • Price$323
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD21006049
  • Product description(2S,3R,4S)-2-Amino-4-hydroxy-3-methylpentanoicacid 95+%
  • Packaging5g
  • Price$1283
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDCZ-279
  • Product description4-Hydroxyisoleucine >98%
  • Packaging20mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number50118
  • Product description(4S)-4-Hydroxy-L-isoleucine from fenugreek seed, ≥98.0% (TLC)
  • Packaging50mg
  • Price$527
  • Updated2024-03-01
  • Buy
  • ManufacturerSynQuest Laboratories
  • Product number4157-1-45
  • Product description(4S)-4-Hydroxy-L-isoleucine from fenugre
  • Packaging20mg
  • Price$264
  • Updated2021-12-16
  • Buy
  • ManufacturerSynQuest Laboratories
  • Product number4157-1-45
  • Product description(4S)-4-Hydroxy-L-isoleucine from fenugre
  • Packaging50mg
  • Price$544
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberH943570
  • Product description(4S)-4-Hydroxy-L-isoleucine
  • Packaging25mg
  • Price$1455
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4577CQ Hydroxyisoleucine 1mg $174 2021-12-16 Buy
Arctom SY232484 4-Hydroxyisoleucine ≥98% 10mg $300 2021-12-16 Buy
Cayman Chemical 11812 4-Hydroxyisoleucine 1mg $68 2024-03-01 Buy
Cayman Chemical 11812 4-Hydroxyisoleucine 5mg $302 2024-03-01 Buy
Cayman Chemical 11812 4-Hydroxyisoleucine 10mg $535 2024-03-01 Buy
Cayman Chemical 11812 4-Hydroxyisoleucine 25mg $1169 2024-03-01 Buy
Chemenu CM133299 (2S,3R,4S)-2-amino-4-hydroxy-3-methylpentanoicacid 95% 1g $302 2021-12-16 Buy
Chemenu CM133299 (2S,3R,4S)-2-amino-4-hydroxy-3-methylpentanoicacid 95% 5g $1200 2021-12-16 Buy
Crysdot CD21006049 (2S,3R,4S)-2-Amino-4-hydroxy-3-methylpentanoicacid 95+% 1g $323 2021-12-16 Buy
Crysdot CD21006049 (2S,3R,4S)-2-Amino-4-hydroxy-3-methylpentanoicacid 95+% 5g $1283 2021-12-16 Buy
DC Chemicals DCZ-279 4-Hydroxyisoleucine >98% 20mg $280 2021-12-16 Buy
Sigma-Aldrich 50118 (4S)-4-Hydroxy-L-isoleucine from fenugreek seed, ≥98.0% (TLC) 50mg $527 2024-03-01 Buy
SynQuest Laboratories 4157-1-45 (4S)-4-Hydroxy-L-isoleucine from fenugre 20mg $264 2021-12-16 Buy
SynQuest Laboratories 4157-1-45 (4S)-4-Hydroxy-L-isoleucine from fenugre 50mg $544 2021-12-16 Buy
TRC H943570 (4S)-4-Hydroxy-L-isoleucine 25mg $1455 2021-12-16 Buy

Properties

Melting point :223-224℃
Boiling point :331.6±32.0 °C(Predicted)
Density :1.181±0.06 g/cm3 (20 ºC 760 Torr)
Flash point :147℃
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Methanol (Slightly), Water (Slightly)
pka :2.41±0.25(Predicted)
form :Solid
color :White to Off-White
optical activity :[α]/D +32.5±2.0°, c = 1 in H2O
BRN :4128096
InChI :InChI=1S/C6H13NO3/c1-3(4(2)8)5(7)6(9)10/h3-5,8H,7H2,1-2H3,(H,9,10)/t3-,4-,5-/m0/s1
InChIKey :OSCCDBFHNMXNME-YUPRTTJUSA-N
SMILES :C(O)(=O)[C@@H](N)[C@@H](C)[C@H](C)O

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

4-Hydroxyisoleucine is an amino acid that has been found in fenugreek (T. foenum graecum) seeds and has antidiabetic activity. It increases glucose-stimulated insulin release from isolated rat islets and isolated perfused rat pancreas when used at a concentration of 200 μM. In vivo, 4-hydroxyisoleucine increases PI3K activity in muscle and liver in rats when administered at a dose of 18 mg/kg and in muscle in a rat model of type 2 diabetes induced by nicotinamide and streptozotocin (STZ; ) when administered at 25 mg/kg. 4-Hydroxyisoleucine (50 mg/kg per day for four weeks) decreases plasma glucose, triglyceride, LDL, HDL, and cholesterol levels in an STZ-induced rat model of type 1 diabetes.

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