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ChemicalBook >> CAS DataBase List >> Daunorubicin hydrochloride

Daunorubicin hydrochloride

$15 - $1340
Product name: Daunorubicin hydrochloride
CAS: 23541-50-6
MF: C27H29NO10.ClH
MW: 563.98
EINECS:245-723-4
MDL Number:MFCD04974507
Synonyms:5,12-Naphthacenedione,8-acetyl-10-[(3-aMino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-Methoxy-,hydrochloride (1:1), (8S,10S)-;daunoblastin ;daunoblastina ;daunomycinchlorohydrate ;ndc0082-4155 ;ondena ;rp13057hydrochloride ;rubidomycinhydrochloride

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AK Scientific
Alfa Aesar
Ambeed
American Custom Chemicals Corporation
ApexBio Technology
Arctom
AvaChem
Biorbyt Ltd
Cayman Chemical
Chem-Impex
ChemScene
Chemtos
Crysdot
CSNpharm
DC Chemicals
Medical Isotopes, Inc.
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d0125000
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ManufacturerAK Scientific
Product numberQ716
Product descriptionDaunorubicinHCl
Packaging50mg
Price$144
Updated2021-12-16
Buy

ManufacturerAlfa Aesar
Product numberJ60224
Product descriptionDaunorubicin hydrochloride
Packaging10mg
Price$214
Updated2024-03-01
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ManufacturerAmbeed
Product numberA148164
Product description(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+%
Packaging10mg
Price$15
Updated2021-12-16
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ManufacturerAmbeed
Product numberA148164
Product description(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+%
Packaging25mg
Price$18
Updated2021-12-16
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ManufacturerAmbeed
Product numberA148164
Product description(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+%
Packaging50mg
Price$22
Updated2021-12-16
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ManufacturerAmbeed
Product numberA148164
Product description(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+%
Packaging100mg
Price$27
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA148164
Product description(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+%
Packaging250mg
Price$53
Updated2021-12-16
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ManufacturerAmbeed
Product numberA148164
Product description(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+%
Packaging1g
Price$149
Updated2021-12-16
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ManufacturerAmbeed
Product numberA148164
Product description(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+%
Packaging5g
Price$596
Updated2021-12-16
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ManufacturerAmerican Custom Chemicals Corporation
Product numberAPI0002223
Product descriptionDAUNORUBICIN HYDROCHLORIDE 95.00%
Packaging1G
Price$675.15
Updated2021-12-16
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ManufacturerAmerican Custom Chemicals Corporation
Product numberAPI0002223
Product descriptionDAUNORUBICIN HYDROCHLORIDE 95.00%
Packaging5MG
Price$508
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB2285
Product descriptionDaunorubicinHCl
Packaging10mg
Price$50
Updated2021-12-16
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ManufacturerArctom
Product numberAS003082
Product description(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride ≥98%
Packaging10mg
Price$15
Updated2021-12-16
Buy

ManufacturerArctom
Product numberAS003082
Product description(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride ≥98%
Packaging25mg
Price$18
Updated2021-12-16
Buy

ManufacturerArctom
Product numberAS003082
Product description(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride ≥98%
Packaging50mg
Price$22
Updated2021-12-16
Buy

ManufacturerArctom
Product numberAS003082
Product description(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride ≥98%
Packaging100mg
Price$27
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AK Scientific	Q716	DaunorubicinHCl	50mg	$144	2021-12-16	Buy
Alfa Aesar	J60224	Daunorubicin hydrochloride	10mg	$214	2024-03-01	Buy
Ambeed	A148164	(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+%	10mg	$15	2021-12-16	Buy
Ambeed	A148164	(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+%	25mg	$18	2021-12-16	Buy
Ambeed	A148164	(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+%	50mg	$22	2021-12-16	Buy
Ambeed	A148164	(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+%	100mg	$27	2021-12-16	Buy
Ambeed	A148164	(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+%	250mg	$53	2021-12-16	Buy
Ambeed	A148164	(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+%	1g	$149	2021-12-16	Buy
Ambeed	A148164	(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride 98+%	5g	$596	2021-12-16	Buy
American Custom Chemicals Corporation	API0002223	DAUNORUBICIN HYDROCHLORIDE 95.00%	1G	$675.15	2021-12-16	Buy
American Custom Chemicals Corporation	API0002223	DAUNORUBICIN HYDROCHLORIDE 95.00%	5MG	$508	2021-12-16	Buy
ApexBio Technology	B2285	DaunorubicinHCl	10mg	$50	2021-12-16	Buy
Arctom	AS003082	(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride ≥98%	10mg	$15	2021-12-16	Buy
Arctom	AS003082	(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride ≥98%	25mg	$18	2021-12-16	Buy
Arctom	AS003082	(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride ≥98%	50mg	$22	2021-12-16	Buy
Arctom	AS003082	(8S,10S)-8-Acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dionehydrochloride ≥98%	100mg	$27	2021-12-16	Buy

Next Last

Properties

Melting point :190°C (dec)
alpha :D20 +248 ±5° (c = 0.05-0.1 in methanol)
storage temp. :Inert atmosphere,2-8°C
solubility :Freely soluble in water and in methanol, slightly soluble in alcohol, practically insoluble in acetone.
form :solid
color :red to deep red
Water Solubility :Soluble in water (50 mM)
Sensitive :Hygroscopic
λmax :477nm(H2O)(lit.)
Merck :14,2832
BRN :4229221
Stability :Stability
InChIKey :GUGHGUXZJWAIAS-SMLRDAARNA-N
SMILES :C1=CC2C(=O)C3=C(O)C4C[C@](C(C)=O)(O)C[C@H](O[C@@H]5O[C@@H](C)[C@@H](O)[C@@H](N)C5)C=4C(O)=C3C(=O)C=2C(OC)=C1.Cl |&1:10,16,18,20,22,24,r|
EPA Substance Registry System :Daunorubicin hydrochloride (23541-50-6)

Safety Information

Symbol(GHS):

Signal word:

Danger

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H301	Toxic if swalloed	Acute toxicity,oral	Category 3	Danger	P264, P270, P301+P310, P321, P330,P405, P501
H341	Suspected of causing genetic defects	Germ cell mutagenicity	Category 2	Warning	P201,P202, P281, P308+P313, P405,P501
H351	Suspected of causing cancer	Carcinogenicity	Category 2	Warning	P201, P202, P281, P308+P313, P405,P501

Precautionary statements:

P201	Obtain special instructions before use.
P202	Do not handle until all safety precautions have been read and understood.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Daunorubicin is an antitumor antibiotic widely used in the treatment of acute myeloid leukemias (AMLs). At 0.2-1μM, daunorubicin induces apoptosis in mature monocytic U937 and myelocytic HL-60 AML cells. However, immature AML cells (CD 34+-KG1a, -KG1, or -HEL cells) appear resistant to apoptosis at similar concentrations. In mature AML cells, daunorubicin has been shown to trigger a ROS-dependent sphingomyelin-ceramide pathway that activates the MEKK1-SEK1-JNK cascade leading to enhanced DNA binding activity of the transcription factor AP-1.

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Suppliers and manufacturers

Hebei Weibang Biotechnology Co., Ltd

$1.00 /1kg
Daunorubicin hydrochloride / Daunorubicin hcl CAS:23541-50-6

Hebei Chuanghai Biotechnology Co,.LTD

$100.00 /1kg
Daunorubicin Hydrochloride CAS:23541-50-6

Henan Bao Enluo International TradeCo.，LTD

$50.00 /1kg
Daunorubicin hydrochloride CAS:23541-50-6

Apeloa production Co.,Limited

$1.00 /1g
Daunorubicin HCl CAS:23541-50-6

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.

$0.00 /1g
Daunorubicin Hydrochloride CAS:23541-50-6

Hebei Zhuanglai Chemical Trading Co Ltd

$150.00 /1kg
Daunorubicin HCl CAS:23541-50-6

Hubei XinRunde Chemical Co., Ltd.

$10.00 /1KG
Daunomycin Hydrochloride 23541-50-6 CAS:23541-50-6

Protheragen-ING

Henan Tianfu Chemical Co.,Ltd.

Shanghai Yingrui Biopharma Co., Ltd.

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Daunorubicin hydrochloride

Properties

Safety Information

Description

Related product price

Suppliers and manufacturers