4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole
![4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole price.](/CAS2/GIF/210690-85-0.gif)
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- $100 - $1815
- Product name: 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole
- CAS: 210690-85-0
- MF: C30H57NO2SSi2
- MW: 552.02
- EINECS:
- MDL Number:MFCD04039436
- Synonyms:4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole;4-[(1E,3S,5Z,10S)-3,11-Bis[[(1,1-diMethylethyl)diMethylsilyl]oxy]-2,6,10-triMethyl-1,5-undecadien-1-yl]-2-Methyl-thiazole;Thiazole, 4-[(1E,3S,5Z,10S)-3,11-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2,6,10-trimethyl-1,5-undecadien-1-yl]-2-methyl-;Paclitaxel Impurity 75
11 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Biosynth Carbosynth
- TRC
Package
- 100mg
- 250MG
- 500mg
- 1g
- 2g
- 2.5G
- ManufacturerAK Scientific
- Product number4493DN
- Product descriptionTert-butyl-[(2S,9S)-9-[tert-butyl(dimethyl)silyl]oxy-2,6,10-trimethyl-11-(2-methyl-1,3-thiazol-4-yl)undeca-6,10-dienoxy]-dimethylsilane
- Packaging500mg
- Price$502
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberORS0001373
- Product description4-((1E,3S,5Z,8R/S,10S)-3,11-BIS-((TERT-BUTYL(DIMETHYL)SILYL)OXY)-2,6,10-TRIMETHYL-UNDECA-1,5-DIENYL)-2-METHYL-1,3-THIAZOLE 95.00%
- Packaging250MG
- Price$721.88
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberORS0001373
- Product description4-((1E,3S,5Z,8R/S,10S)-3,11-BIS-((TERT-BUTYL(DIMETHYL)SILYL)OXY)-2,6,10-TRIMETHYL-UNDECA-1,5-DIENYL)-2-METHYL-1,3-THIAZOLE 95.00%
- Packaging2.5G
- Price$1815
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB18799
- Product description4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole
- Packaging100mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB18799
- Product description4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole
- Packaging250mg
- Price$182.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB18799
- Product description4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole
- Packaging500mg
- Price$335
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB18799
- Product description4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole
- Packaging1g
- Price$600.6
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB18799
- Product description4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole
- Packaging2g
- Price$1092
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberB415890
- Product description4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole
- Packaging250mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberB415890
- Product description4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole
- Packaging2g
- Price$880
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberB415890
- Product description4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole
- Packaging2.5g
- Price$1100
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 4493DN | Tert-butyl-[(2S,9S)-9-[tert-butyl(dimethyl)silyl]oxy-2,6,10-trimethyl-11-(2-methyl-1,3-thiazol-4-yl)undeca-6,10-dienoxy]-dimethylsilane | 500mg | $502 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | ORS0001373 | 4-((1E,3S,5Z,8R/S,10S)-3,11-BIS-((TERT-BUTYL(DIMETHYL)SILYL)OXY)-2,6,10-TRIMETHYL-UNDECA-1,5-DIENYL)-2-METHYL-1,3-THIAZOLE 95.00% | 250MG | $721.88 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | ORS0001373 | 4-((1E,3S,5Z,8R/S,10S)-3,11-BIS-((TERT-BUTYL(DIMETHYL)SILYL)OXY)-2,6,10-TRIMETHYL-UNDECA-1,5-DIENYL)-2-METHYL-1,3-THIAZOLE 95.00% | 2.5G | $1815 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB18799 | 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole | 100mg | $100 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB18799 | 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole | 250mg | $182.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB18799 | 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole | 500mg | $335 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB18799 | 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole | 1g | $600.6 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB18799 | 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole | 2g | $1092 | 2021-12-16 | Buy |
| TRC | B415890 | 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole | 250mg | $140 | 2021-12-16 | Buy |
| TRC | B415890 | 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole | 2g | $880 | 2021-12-16 | Buy |
| TRC | B415890 | 4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole | 2.5g | $1100 | 2021-12-16 | Buy |
Properties
Boiling point :550.1±50.0 °C(Predicted)
Density :0.939±0.06 g/cm3(Predicted)
solubility :Chloroform, Dichloromethane, Ethanol, Ethyl Acetate, Methanol, Toluene
form :Oil
pka :2.73±0.10(Predicted)
color :Colourless
Density :0.939±0.06 g/cm3(Predicted)
solubility :Chloroform, Dichloromethane, Ethanol, Ethyl Acetate, Methanol, Toluene
form :Oil
pka :2.73±0.10(Predicted)
color :Colourless
Safety Information
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Description
An intermediate in the synthesis of Epothilones. Epothilones are polyketide natural products that inhibit cancer cells by a mechanism similar to paclitaxel, and also are effective against paclitaxel-resistant tumours. Epothilone D is in phase I clinical testing of in patients with advanced solid tumours. Epothilone D is a cytotoxic macrolide that stabilises malignant cells' microtubules and arrests mitosis, a characteristic it shares with other epothilones. They bind to the same hepatic sites as does paclitaxel (Taxol) in a 1:1 stoichiometric ratio of a, b-tubulin heterodimers.More related product prices
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