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ChemicalBook >> CAS DataBase List >> (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride

$48 - $21666
Product name: (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride
CAS: 149690-12-0
MF: C20H26ClNO2
MW: 347.88
EINECS:695-675-7
MDL Number:MFCD27955983
Synonyms:(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate HCl;LCZ696 Intermediate2;LCZ698;[1,1'-Biphenyl]-4-pentanoic acid, γ-amino-α-methyl-, ethyl ester, hydrochloride (1:1), (αR,γS)-;(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate;(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate hydrochloride;(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride;(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride (1:1)

Price19 Properties Safety Information Description

19 prices

Selected condition：

Brand

AccelPharmtech
AK Scientific
Alichem
Ambeed
Chemenu
Crysdot
Labseeker
TRC

Package

50mg
1G
5G
10g
25G
100g
1000g
1kg

ManufacturerAccelPharmtech
Product numberXP1500
Product description(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%
Packaging1G
Price$230
Updated2021-12-16
Buy

ManufacturerAccelPharmtech
Product numberXP1500
Product description(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%
Packaging5G
Price$280
Updated2021-12-16
Buy

ManufacturerAccelPharmtech
Product numberXP1500
Product description(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%
Packaging25G
Price$710
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number2498DC
Product description(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride
Packaging25g
Price$870
Updated2021-12-16
Buy

ManufacturerAlichem
Product number149690120
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride
Packaging5g
Price$157.5
Updated2021-12-16
Buy

ManufacturerAlichem
Product number149690120
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride
Packaging10g
Price$250
Updated2021-12-16
Buy

ManufacturerAlichem
Product number149690120
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride
Packaging25g
Price$490
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA249066
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%
Packaging1g
Price$48
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA249066
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%
Packaging5g
Price$135
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA249066
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%
Packaging10g
Price$241
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA249066
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%
Packaging25g
Price$404
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA249066
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%
Packaging100g
Price$1192
Updated2021-12-16
Buy

ManufacturerChemenu
Product numberCM244548
Product description(2R,4S)-Ethyl5-([1,1''-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%
Packaging1000g
Price$1748
Updated2021-12-16
Buy

ManufacturerCrysdot
Product numberCD12139848
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%
Packaging1g
Price$50
Updated2021-12-16
Buy

ManufacturerCrysdot
Product numberCD12139848
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%
Packaging5g
Price$150
Updated2021-12-16
Buy

ManufacturerCrysdot
Product numberCD12139848
Product description(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%
Packaging10g
Price$250
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AccelPharmtech	XP1500	(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%	1G	$230	2021-12-16	Buy
AccelPharmtech	XP1500	(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%	5G	$280	2021-12-16	Buy
AccelPharmtech	XP1500	(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 99%	25G	$710	2021-12-16	Buy
AK Scientific	2498DC	(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride	25g	$870	2021-12-16	Buy
Alichem	149690120	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride	5g	$157.5	2021-12-16	Buy
Alichem	149690120	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride	10g	$250	2021-12-16	Buy
Alichem	149690120	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride	25g	$490	2021-12-16	Buy
Ambeed	A249066	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%	1g	$48	2021-12-16	Buy
Ambeed	A249066	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%	5g	$135	2021-12-16	Buy
Ambeed	A249066	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%	10g	$241	2021-12-16	Buy
Ambeed	A249066	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%	25g	$404	2021-12-16	Buy
Ambeed	A249066	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%	100g	$1192	2021-12-16	Buy
Chemenu	CM244548	(2R,4S)-Ethyl5-([1,1''-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%	1000g	$1748	2021-12-16	Buy
Crysdot	CD12139848	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%	1g	$50	2021-12-16	Buy
Crysdot	CD12139848	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%	5g	$150	2021-12-16	Buy
Crysdot	CD12139848	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%	10g	$250	2021-12-16	Buy

Next Last

Properties

Melting point :155 - 162°C
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White
Stability :Hygroscopic
InChI :InChI=1/C20H25NO2.ClH/c1-3-23-20(22)15(2)13-19(21)14-16-9-11-18(12-10-16)17-7-5-4-6-8-17;/h4-12,15,19H,3,13-14,21H2,1-2H3;1H/t15-,19+;/s3
InChIKey :MYJTZLYRAWUSLB-MTPCZXHRNA-N
SMILES :C(C1C=CC(C2C=CC=CC=2)=CC=1)[C@@H](N)C[C@@H](C)C(=O)OCC.Cl |&1:13,16,r|

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is used as a reagent in the synthesis of LCZ696, an angiotensin II receptor and neprilysin receptor dual inhibitor. (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is also used as a reagent in the preparation of novel NEP inhibitor prodrugs for the treatment of hypertension and cardiovascular diseases.

More related product prices

Sacubitril Impurity 7 AHU-377 (heMicalciuM salt) Valsartan (R,E)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- N-[2’-(1H-tetrazol-5-yl)biphenyl-4-yl methyl]-N-Valeryl-(L)-Valine benzyl ester sacubitril (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoic acid 1426129-50-1 enantioMer BOC-D-4,4'-BIPHENYLALANINE Valsartan n-Propyl 5717-37-3 L-Valine, N-(1-oxopentyl-d9)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]- 4'-Methyl-2-cyanobiphenyl LCZ696 InteMediate 5-[2-(4'-METHYLBIPHENYL)]TETRAZOLE valsartan S)-2-(((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)aMino)-3- Methylbutanoic acid N-[2’-(1H-tetrazol-5-yl)biphenyl-4-yl methyl]-N-Valeryl-(L)-Valine methyl ester

Suppliers and manufacturers

career henan chemical co

$100.00 /1KG
(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate CAS:149690-12-0

ChemExpress

Capot Chemical Co.,Ltd.

Shanghai Daken Advanced Materials Co.,Ltd

Beijing Cooperate Pharmaceutical Co.,Ltd

Henan Tianfu Chemical Co.,Ltd.

ATK CHEMICAL COMPANY LIMITED

Jinan Finer Chemical Co., Ltd

HubeiwidelychemicaltechnologyCo.,Ltd

Standardpharm Co. Ltd.

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(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride

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Description

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