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ChemicalBook >> CAS DataBase List >> 1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one

1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one

1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one price.
  • $57 - $2250
  • Product name: 1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one
  • CAS: 137977-97-0
  • MF: C18H17ClN2O2
  • MW: 328.79
  • EINECS:1592732-453-0
  • MDL Number:MFCD19440799
  • Synonyms:1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one;5H-1-Benzazepin-5-one, 1-(4-aMino-2-Methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-;1,2,3,4-Tetrahydro-1-(4-amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one;1-(4-aMino-2-Methylbenzoyl)-7-chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one;1-(4-Amino-2-Methylbenzoyl)-7-Chloro-1,2,3,4-Tetrahydro-5H-1-benzazepine-5-One;1-(4-amino-2-methylbenzoyl)-7-chloro-3,4-dihydro-2H-1-benzazepin-5-one;Tolvaptan Intermediate 3;1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1...
14 prices
Selected condition：
Brand
  • AK Scientific
  • Alichem
  • Ambeed
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Chemenu
  • Crysdot
  • Medical Isotopes, Inc.
Package
  • 5MG
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 2g
  • 5G
  • ManufacturerAK Scientific
  • Product numberZ3611
  • Product description7-Chloro-1-(4-amino-2-methylbenzoyl)-1,2,3,4-tetrahydrobenzo[b]azepin-5-one
  • Packaging250mg
  • Price$131
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number137977970
  • Product description1-(4-Amino-2-methylbenzoyl)-7-chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one
  • Packaging1g
  • Price$152.6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA147201
  • Product description1-(4-Amino-2-methylbenzoyl)-7-chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one 98%
  • Packaging100mg
  • Price$57
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA147201
  • Product description1-(4-Amino-2-methylbenzoyl)-7-chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one 98%
  • Packaging250mg
  • Price$89
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA147201
  • Product description1-(4-Amino-2-methylbenzoyl)-7-chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one 98%
  • Packaging1g
  • Price$186
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0361932
  • Product description1-(4-AMINO-2-METHYLBENZOYL)-7-CHLORO-3,4-DIHYDRO-1H-BENZO[B]AZEPIN-5(2H)-ONE 95.00%
  • Packaging5MG
  • Price$495.24
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA151721
  • Product description1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one
  • Packaging250mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA151721
  • Product description1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one
  • Packaging500mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA151721
  • Product description1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one
  • Packaging1g
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA151721
  • Product description1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one
  • Packaging2g
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA151721
  • Product description1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one
  • Packaging5G
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM160282
  • Product description1-(4-amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one 95%
  • Packaging5g
  • Price$518
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD12147006
  • Product description1-(4-Amino-2-methylbenzoyl)-7-chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one 95+%
  • Packaging5g
  • Price$554
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number62015
  • Product description1,2,3,4-Tetrahydro-1-(4-amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one
  • Packaging5G
  • Price$2250
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Z3611 7-Chloro-1-(4-amino-2-methylbenzoyl)-1,2,3,4-tetrahydrobenzo[b]azepin-5-one 250mg $131 2021-12-16 Buy
Alichem 137977970 1-(4-Amino-2-methylbenzoyl)-7-chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one 1g $152.6 2021-12-16 Buy
Ambeed A147201 1-(4-Amino-2-methylbenzoyl)-7-chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one 98% 100mg $57 2021-12-16 Buy
Ambeed A147201 1-(4-Amino-2-methylbenzoyl)-7-chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one 98% 250mg $89 2021-12-16 Buy
Ambeed A147201 1-(4-Amino-2-methylbenzoyl)-7-chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one 98% 1g $186 2021-12-16 Buy
American Custom Chemicals Corporation HCH0361932 1-(4-AMINO-2-METHYLBENZOYL)-7-CHLORO-3,4-DIHYDRO-1H-BENZO[B]AZEPIN-5(2H)-ONE 95.00% 5MG $495.24 2021-12-16 Buy
Biosynth Carbosynth FA151721 1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one 250mg $60 2021-12-16 Buy
Biosynth Carbosynth FA151721 1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one 500mg $100 2021-12-16 Buy
Biosynth Carbosynth FA151721 1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one 1g $150 2021-12-16 Buy
Biosynth Carbosynth FA151721 1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one 2g $250 2021-12-16 Buy
Biosynth Carbosynth FA151721 1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one 5G $400 2021-12-16 Buy
Chemenu CM160282 1-(4-amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one 95% 5g $518 2021-12-16 Buy
Crysdot CD12147006 1-(4-Amino-2-methylbenzoyl)-7-chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one 95+% 5g $554 2021-12-16 Buy
Medical Isotopes, Inc. 62015 1,2,3,4-Tetrahydro-1-(4-amino-2-methylbenzoyl)-7-chloro-5H-1-benzazepin-5-one 5G $2250 2021-12-16 Buy

Properties

Melting point :186-189°C
Boiling point :565.4±50.0 °C(Predicted)
Density :1.320
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
pka :2.28±0.10(Predicted)
form :Solid
color :Off-White to Pale Yellow
InChI :InChI=1S/C18H17ClN2O2/c1-11-9-13(20)5-6-14(11)18(23)21-8-2-3-17(22)15-10-12(19)4-7-16(15)21/h4-7,9-10H,2-3,8,20H2,1H3
InChIKey :FLJCJPKXJWRZJB-UHFFFAOYSA-N
SMILES :N1(C(=O)C2=CC=C(N)C=C2C)C2=CC=C(Cl)C=C2C(=O)CCC1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one is an intermediate used in the synthetic preparation of Tolvaptan (T536650), a selective nonpeptide arginine vasopressin V 2 receptor antagonist.