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ChemicalBook >> CAS DataBase List >> 4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide

4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide

4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide price.
  • $287 - $1695
  • Product name: 4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide
  • CAS: 1216626-17-3
  • MF: C17H22D5N3O4S
  • MW: 374.50978889
  • EINECS:
  • MDL Number:
  • Synonyms:[2H5]-Amisulpride;Amisulpride Impurity 27;Amisulpride Hydrochloride D5Q: What is Amisulpride Hydrochloride D5 Q: What is the CAS Number of Amisulpride Hydrochloride D5 Q: What is the storage condition of Amisulpride Hydrochloride D5 Q: What are the applications of Amisulpride Hydrochloride D5;4-amino-5-ethylsulfonyl-2-methoxy-N-[[1-(1,1,2,2,2-pentadeuterioethyl)pyrrolidin-2-yl]methyl]benzamide;Guaiacol Impurity 28;4-amino-5-(ethanesulfonyl)-N-({1-[(1,1,2,2,2-2H?)ethyl]pyrrolidin-2-yl}methyl)-2-methoxybenzamide
3 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number8546DF
  • Product descriptionAmisulpride-d5
  • Packaging1mg
  • Price$403
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number30075
  • Product descriptionAmisulpride-d5
  • Packaging1mg
  • Price$287
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberA633252
  • Product descriptionAmisulpride-d5
  • Packaging10mg
  • Price$1695
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8546DF Amisulpride-d5 1mg $403 2021-12-16 Buy
Cayman Chemical 30075 Amisulpride-d5 1mg $287 2024-03-01 Buy
TRC A633252 Amisulpride-d5 10mg $1695 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :Chloroform: slightly soluble,Methanol: slightly soluble
form :A solid
color :White to off-white
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Amisulpride-d5 is intended for use as an internal standard for the quantification of amisulpride by GC- or LC-MS. Amisulpride is a dopamine D2 and D3 receptor antagonist (Kis = 3 and 3.5 nM, respectively). It is also an antagonist of the serotonin (5-HT) receptor subtypes 5-HT2B, 5-HT7, and 5-HT7A (Kis = 13, 11.5, and 135.5 nM, respectively). It is selective for these receptors over a panel of 39 additional receptors, ion channels, and transporters (Kis = >1,000 nM for all). Amisulpride increases 7-OH-DPAT-induced decreases in dopamine and acetylcholine release in electrically stimulated rat striatal slices (EC50s = 2.2 and 1.2 nM, respectively). It increases the levels of dopamine and the dopamine metabolite 3,4-dihydroxyphenylacetic acid (DOPAC) in rat striatum and nucleus accumbens when administered intraperitoneally at a dose of 10 mg/kg. Amisulpride decreases immobility time in the forced swim test in rats, as well as reduces stress-induced decreases in sucrose consumption in a rat model of depression induced by chronic mild stress.