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ChemicalBook >> CAS DataBase List >> N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea

N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea

N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea price.
  • $33 - $1800
  • Product name: N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
  • CAS: 1207360-89-1
  • MF: C24H32N6O3
  • MW: 452.55
  • EINECS:200-258-5
  • MDL Number:MFCD22417087
  • Synonyms:GDC-0349;N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea;RG-7603;Urea, N-ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]-;GDC-0349 N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea;(S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea;(S)-1-Ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimi;CS-695
18 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 500μg
  • 1mg
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 250mg
  • 10mM(in 1mL DMSO)
  • 100mg
  • ManufacturerAK Scientific
  • Product number2427AH
  • Product description1-Ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
  • Packaging10mg
  • Price$414
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2427AH
  • Product description1-Ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
  • Packaging25mg
  • Price$779
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0017259
  • Product descriptionGDC-0349 95.00%
  • Packaging5MG
  • Price$381.7
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1642
  • Product description1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1642
  • Product description1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
  • Packaging10mM(in 1mL DMSO)
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1642
  • Product description1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
  • Packaging25mg
  • Price$480
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1642
  • Product description1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
  • Packaging100mg
  • Price$1200
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number24058
  • Product descriptionGDC-0349 ≥98%
  • Packaging500μg
  • Price$33
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24058
  • Product descriptionGDC-0349 ≥98%
  • Packaging1mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24058
  • Product descriptionGDC-0349 ≥98%
  • Packaging5mg
  • Price$238
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24058
  • Product descriptionGDC-0349 ≥98%
  • Packaging10mg
  • Price$443
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0700
  • Product descriptionGDC-0349 98.20%
  • Packaging5mg
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0700
  • Product descriptionGDC-0349 98.20%
  • Packaging10mg
  • Price$216
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0700
  • Product descriptionGDC-0349 98.20%
  • Packaging50mg
  • Price$948
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004284
  • Product descriptionGDC-0349 98+%
  • Packaging5mg
  • Price$77
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004284
  • Product descriptionGDC-0349 98+%
  • Packaging10mg
  • Price$140
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2427AH 1-Ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea 10mg $414 2021-12-16 Buy
AK Scientific 2427AH 1-Ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea 25mg $779 2021-12-16 Buy
American Custom Chemicals Corporation API0017259 GDC-0349 95.00% 5MG $381.7 2021-12-16 Buy
ApexBio Technology A1642 1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea 5mg $120 2021-12-16 Buy
ApexBio Technology A1642 1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea 10mM(in 1mL DMSO) $120 2021-12-16 Buy
ApexBio Technology A1642 1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea 25mg $480 2021-12-16 Buy
ApexBio Technology A1642 1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea 100mg $1200 2021-12-16 Buy
Cayman Chemical 24058 GDC-0349 ≥98% 500μg $33 2024-03-01 Buy
Cayman Chemical 24058 GDC-0349 ≥98% 1mg $62 2024-03-01 Buy
Cayman Chemical 24058 GDC-0349 ≥98% 5mg $238 2024-03-01 Buy
Cayman Chemical 24058 GDC-0349 ≥98% 10mg $443 2024-03-01 Buy
ChemScene CS-0700 GDC-0349 98.20% 5mg $132 2021-12-16 Buy
ChemScene CS-0700 GDC-0349 98.20% 10mg $216 2021-12-16 Buy
ChemScene CS-0700 GDC-0349 98.20% 50mg $948 2021-12-16 Buy
Crysdot CD31004284 GDC-0349 98+% 5mg $77 2021-12-16 Buy
Crysdot CD31004284 GDC-0349 98+% 10mg $140 2021-12-16 Buy

Properties

Boiling point :571.3±50.0 °C(Predicted)
Density :1.269
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:9): 0.1 mg/ml; Ethanol: 10 mg/ml
form :Powder
pka :13.87±0.46(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea is a potent and selective mTOR inhibitor with dose-dependent efficacy in mouse x enograft cancer models.