1-[4-[(2,3,3-Trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylicacid
![1-[4-[(2,3,3-Trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylicacid price.](/CAS/GIF/1160514-60-2.gif)
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- $32 - $13597.5
- Product name: 1-[4-[(2,3,3-Trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylicacid
- CAS: 1160514-60-2
- MF: C16H11Cl3F3N3O3
- MW: 456.63
- EINECS:
- MDL Number:MFCD00178741
- Synonyms:1-[4-[(2,3,3-Trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylicacid;Ethyl-1-(4-(2,3,3-trichloroacrylamide)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate;TRPC3 Channel Inhibitor, Pyr3 ;1-[4-(2,3,3-Trichloro-acryloylamino)-phenyl]-5-trifluoromethyl-1H-pyrazole-4-carboxylic acid ethyl ester;TRPC3 Channel Inhibitor, Pyr3 - CAS 1160514-60-2 - Calbiochem;1H-Pyrazole-4-carboxylic acid, 1-[4-[(2,3,3-trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5-(trifluoromethyl)-, ethyl ester;Pyr3;Pyr3,Pyr-3
23 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 5mg
- 25mg
- 50
- 1MG
- 10mg
- 50MG
- 100mg
- 250MG
- 500MG
- ManufacturerAK Scientific
- Product number2175DN
- Product descriptionEthyl1-[4-(2,3,3-trichloroprop-2-enoylamino)phenyl]-5-(trifluoromethyl)pyrazole-4-carboxylate
- Packaging10mg
- Price$286
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001009
- Product descriptionPYR3 95.00%
- Packaging1MG
- Price$135.45
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001009
- Product descriptionPYR3 95.00%
- Packaging10MG
- Price$709.46
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001009
- Product descriptionPYR3 95.00%
- Packaging50MG
- Price$1230.95
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001009
- Product descriptionPYR3 95.00%
- Packaging250MG
- Price$6982.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001009
- Product descriptionPYR3 95.00%
- Packaging500MG
- Price$13597.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7494
- Product descriptionPyr3
- Packaging5mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7494
- Product descriptionPyr3
- Packaging10mg
- Price$192
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16888
- Product descriptionPyr3 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16888
- Product descriptionPyr3 ≥98%
- Packaging5mg
- Price$116
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16888
- Product descriptionPyr3 ≥98%
- Packaging10mg
- Price$169
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0028846
- Product descriptionPyr3 99.90%
- Packaging5mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0028846
- Product descriptionPyr3 99.90%
- Packaging10mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0028846
- Product descriptionPyr3 99.90%
- Packaging25mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0028846
- Product descriptionPyr3 99.90%
- Packaging50mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number48450
- Product descriptionPyr3
- Packaging25mg
- Price$750
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2175DN | Ethyl1-[4-(2,3,3-trichloroprop-2-enoylamino)phenyl]-5-(trifluoromethyl)pyrazole-4-carboxylate | 10mg | $286 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001009 | PYR3 95.00% | 1MG | $135.45 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001009 | PYR3 95.00% | 10MG | $709.46 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001009 | PYR3 95.00% | 50MG | $1230.95 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001009 | PYR3 95.00% | 250MG | $6982.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001009 | PYR3 95.00% | 500MG | $13597.5 | 2021-12-16 | Buy |
| ApexBio Technology | B7494 | Pyr3 | 5mg | $130 | 2021-12-16 | Buy |
| ApexBio Technology | B7494 | Pyr3 | 10mg | $192 | 2021-12-16 | Buy |
| Cayman Chemical | 16888 | Pyr3 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 16888 | Pyr3 ≥98% | 5mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 16888 | Pyr3 ≥98% | 10mg | $169 | 2024-03-01 | Buy |
| ChemScene | CS-0028846 | Pyr3 99.90% | 5mg | $80 | 2021-12-16 | Buy |
| ChemScene | CS-0028846 | Pyr3 99.90% | 10mg | $120 | 2021-12-16 | Buy |
| ChemScene | CS-0028846 | Pyr3 99.90% | 25mg | $250 | 2021-12-16 | Buy |
| ChemScene | CS-0028846 | Pyr3 99.90% | 50mg | $420 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 48450 | Pyr3 | 25mg | $750 | 2021-12-16 | Buy |
Properties
Melting point :151-153 °C(Solv: toluene (108-88-3))
Boiling point :534.0±50.0 °C(Predicted)
Density :1.54±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO (up to 40 mg/ml).
form :powder
pka :9.97±0.70(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Boiling point :534.0±50.0 °C(Predicted)
Density :1.54±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO (up to 40 mg/ml).
form :powder
pka :9.97±0.70(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Description
Pyr3 is a pyrazole compound that selectively antagonizes the transient receptor potential canonical channel 3 (TRPC3). It inhibits TRPC3-mediated Ca2+ influx with an IC50 value of 0.7 μM without effect on other TRPC members and suppresses activation of nuclear factor of activated T cells with an IC50 value of 0.05 μM. Pyr3 has been shown to suppress cardiac hypertrophy in mice at 0.1 mg/kg/day.Related product price
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