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ChemicalBook >> CAS DataBase List >> 2-(4-(5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-ylamino)ethanolhydrochloride

2-(4-(5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-ylamino)ethanolhydrochloride

2-(4-(5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-ylamino)ethanolhydrochloride price.
  • $45 - $2600
  • Product name: 2-(4-(5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-ylamino)ethanolhydrochloride
  • CAS: 1094042-01-9
  • MF: C23H27N3O4
  • MW: 409.48
  • EINECS:
  • MDL Number:MFCD12912402
  • Synonyms:2-(4-(5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-ylamino)ethanolhydrochloride;CYM 5442 hydrochloride;CYM 5442;2-(4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-ylamino)ethanol;CYM5442 , 1094042-01-9;Ethanol, 2-[[4-[5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]amino]-;CYM 5442 HCl;CYM 5442;CYM-5442
24 prices
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Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 5mg
  • 1mg
  • 50
  • 10MG
  • 25mg
  • 50MG
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2809DC
  • Product description2-({4-[5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl}amino)ethan-1-ol
  • Packaging5mg
  • Price$257
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2809DC
  • Product description2-({4-[5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl}amino)ethan-1-ol
  • Packaging25mg
  • Price$665
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberLIP0000532
  • Product descriptionCYM-5442 95.00%
  • Packaging10MG
  • Price$745.85
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberLIP0000532
  • Product descriptionCYM-5442 95.00%
  • Packaging50MG
  • Price$1417.71
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7441
  • Product descriptionCYM5442hydrochloride
  • Packaging5mg
  • Price$162
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7441
  • Product descriptionCYM5442hydrochloride
  • Packaging10mg
  • Price$258
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7441
  • Product descriptionCYM5442hydrochloride
  • Packaging25mg
  • Price$581
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16925
  • Product descriptionCYM 5442 ≥95%
  • Packaging1mg
  • Price$49
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16925
  • Product descriptionCYM 5442 ≥95%
  • Packaging5mg
  • Price$143
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16925
  • Product descriptionCYM 5442 ≥95%
  • Packaging10mg
  • Price$229
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16925
  • Product descriptionCYM 5442 ≥95%
  • Packaging25mg
  • Price$509
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0002981
  • Product descriptionCYM5442 ≥98.0%
  • Packaging5mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0002981
  • Product descriptionCYM5442 ≥98.0%
  • Packaging10mg
  • Price$360
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004599
  • Product descriptionCYM5442 95+%
  • Packaging100mg
  • Price$285
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004599
  • Product descriptionCYM5442 95+%
  • Packaging1g
  • Price$1140
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8088
  • Product descriptionCYM5442 >98%
  • Packaging250mg
  • Price$1300
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2809DC 2-({4-[5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl}amino)ethan-1-ol 5mg $257 2021-12-16 Buy
AK Scientific 2809DC 2-({4-[5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl}amino)ethan-1-ol 25mg $665 2021-12-16 Buy
American Custom Chemicals Corporation LIP0000532 CYM-5442 95.00% 10MG $745.85 2021-12-16 Buy
American Custom Chemicals Corporation LIP0000532 CYM-5442 95.00% 50MG $1417.71 2021-12-16 Buy
ApexBio Technology B7441 CYM5442hydrochloride 5mg $162 2021-12-16 Buy
ApexBio Technology B7441 CYM5442hydrochloride 10mg $258 2021-12-16 Buy
ApexBio Technology B7441 CYM5442hydrochloride 25mg $581 2021-12-16 Buy
Cayman Chemical 16925 CYM 5442 ≥95% 1mg $49 2024-03-01 Buy
Cayman Chemical 16925 CYM 5442 ≥95% 5mg $143 2024-03-01 Buy
Cayman Chemical 16925 CYM 5442 ≥95% 10mg $229 2024-03-01 Buy
Cayman Chemical 16925 CYM 5442 ≥95% 25mg $509 2024-03-01 Buy
ChemScene CS-0002981 CYM5442 ≥98.0% 5mg $220 2021-12-16 Buy
ChemScene CS-0002981 CYM5442 ≥98.0% 10mg $360 2021-12-16 Buy
Crysdot CD31004599 CYM5442 95+% 100mg $285 2021-12-16 Buy
Crysdot CD31004599 CYM5442 95+% 1g $1140 2021-12-16 Buy
DC Chemicals DC8088 CYM5442 >98% 250mg $1300 2021-12-16 Buy

Properties

Boiling point :617.5±65.0 °C(Predicted)
Density :1.27±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >5mg/mL
form :A crystalline solid
pka :14.73±0.10(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Sphingosine-1-phosphate (S1P) is an extracellular lipid mediator whose major effects are mediated through five distinct G protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. S1P1 is important for vascular development and lymphocyte maturation, migration, and trafficking. CYM 5442 is a full agonist for S1P1 internalization, phosphorylation, and ubiquitination (EC50 = 1.35 nM). It is ineffective at S1P2, S1P3, S1P4, and S1P5 at concentrations up to 10 μM. CYM 5442 has been found to activate S1P1-mediated p42/p44 MAPK phosphorylation in CHO-K1 cells transfected with S1P1 with an EC50 value of 46 nM. At 50 nM, CYM 5442 can induce S1P1-dependent lymphopenia in mice, decreasing B and T cells by 65 and 85%, respectively.

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