Tripropylene glycol
Product identifier
- Product name: Tripropylene glycol
- CBnumber: CB3688489
- CAS: 24800-44-0
- EINECS Number: 246-466-0
- Synonyms: 1,4,7-trimethyl-3,6-dioxaoctane-1,8-diol,TRI(PROPYLENE GLYCOL)
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Not classified.
Label elements
Pictogram(s)
- Signal wordWarning
H303 May be harmfulif swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
none
none
none
none
Other hazards
no data available
Substance
- Product name: Tripropylene glycol
- Synonyms: 1,4,7-trimethyl-3,6-dioxaoctane-1,8-diol,TRI(PROPYLENE GLYCOL)
- CAS: 24800-44-0
- EC number: 246-466-0
- MF: C9H20O4
- MW: 192.25
Description of first aid measures
If inhaledFresh air, rest.
Remove contaminated clothes. Rinse skin with plenty of water or shower.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give one or two glasses of water to drink.
Most important symptoms and effects, both acute and delayed
Non-irritating; no symptoms observed by any exposure route. (USCG, 1999)
Indication of any immediate medical attention and special treatment needed
Absorption, Distribution and ExcretionIs not absorbed through skin in acutely toxic amt even from prolonged & repeated contact.
Extinguishing media
Water, foam, carbon dioxide, dry chemical.
Specific Hazards Arising from the Chemical
Special Hazards of Combustion Products: Acrid fumes of acids and aldehydes may form in fires. (USCG, 1999)
Advice for firefighters
Use water spray, powder, foam, carbon dioxide.
NFPA 704
| HEALTH | 0 | Poses no health hazard, no precautions necessary and would offer no hazard beyond that of ordinary combustible materials | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Collect leaking and spilled liquid in sealable containers as far as possible. Wash away remainder with plenty of water.
Environmental precautions
Collect leaking and spilled liquid in sealable containers as far as possible. Wash away remainder with plenty of water.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Well closed.
Control parameters
Occupational Exposure limit valuesno data available
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear safety spectacles.
Protective gloves.
Use ventilation.
no data available
Information on basic physicochemical properties
- Physical stateLiquid
- Colour
Colourless.
- Odour
ODORLESS
- Melting point/freezing point
< -20 °C. Atm. press.:Ca. 101.3 kPa.
- Boiling point or initial boiling point and boiling range
270 °C. Atm. press.:100.47 kPa.
- Flammability
Combustible.
- Lower and upper explosion limit/flammability limit
no data available
- Flash point
145 °C. Atm. press.:100.11 kPa.
- Auto-ignition temperature
232 °C. Atm. press.:> 101.08 - < 102.33 kPa.
- Decomposition temperature
no data available
- pH
no data available
- Kinematic viscosity
kinematic viscosity (in mm2/s) = 77.3. Temperature:20°C.;kinematic viscosity (in mm2/s) = 23.4. Temperature:40°C.
- Solubility
SOL IN WATER, METHANOL, ETHER
- Partition coefficient n-octanol/water
log Pow = -0.379. Temperature:21.5 °C.;Pow = 0.418. Temperature:21.5 °C.
- Vapour pressure<0.01 mm Hg ( 25 °C)
- Density and/or relative density1.018
- Relative vapour density1.018
- Particle characteristics
no data available
Reactivity
Attacks some plastics.
Chemical stability
no data available
Possibility of hazardous reactions
COMBUSTIBLE.TRIPROPYLENE GLYCOL is a ether-alcohol derivative. The ether being relatively unreactive. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert alcohols to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. May attack some forms of plastics (USCG, 1999).
Conditions to avoid
no data available
Incompatible materials
no data available
Hazardous decomposition products
no data available
Acute toxicity
- Oral: LD50 - rat (male/female) - > 2 000 mg/kg bw.
- Inhalation: LC50 - rat - > 0.083 mg/L air.
- Dermal: LD50 - rabbit (male) - > 16 320 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C.
Toxicity
- Toxicity to fish: LC50 - Oryzias latipes - > 1 000 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - > 1 000 mg/L - 24 h.
- Toxicity to algae: EC50 - Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum) - > 1 000 mg/L - 72 h.
- Toxicity to microorganisms: EC50 - activated sludge of a predominantly domestic sewage - > 1 000 mg/L - 3 h. Remarks:Respiration rate.
Persistence and degradability
By analogy to dipropylene glycol, a structurally similar compound, tripropylene glycol is expected to be resistant to biodegradation(SRC). Polypropylene glycol-utilizing bacteria were isolated by enrichment culture; one strain from this culture was able to grow using various polypropylene glycols (diol and triol types) as a carbon source(1). Dipropylene glycol in a five day BOD test, reached 0(2)-5%(3) of the theoretical oxygen demand. Over a four week period with dipropylene glycol added at 30 mg/L, only 0-3% by BOD was degraded(4). Biodegradation of dipropylene glycol proceeds through the oxidation of terminal alcohol groups leading to the cleavage of the ether linkage(1).
Bioaccumulative potential
An estimated BCF value of 0 was calculated for tripropylene glycol(SRC), using an estimated log Kow of -0.50(1,SRC) and a recommended regression-derived equation(2). According to a recommended classification scheme(3), this BCF value indicates that bioconcentration in aquatic organisms will not be an important fate process(SRC).
Mobility in soil
The Koc of tripropylene glycol is estimated as approximately 13(SRC), using an estimated log Kow of -0.50(1,SRC) and a regression-derived equation(2,SRC). According to a recommended classification scheme(3), this estimated Koc value suggests that tripropylene glycol has very high mobility in soil(SRC).
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: UN3077 (For reference only, please check.)
IMDG: UN3077 (For reference only, please check.)
IATA: UN3077 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)
IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)
IATA: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 9 (For reference only, please check.)
IMDG: 9 (For reference only, please check.)
IATA: 9 (For reference only, please check.)
Packing group, if applicable
ADR/RID: III (For reference only, please check.)
IMDG: III (For reference only, please check.)
IATA: III (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Health effects of exposure to the substance have been investigated, but none has been found.
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.