N,N'-Dimethylpiperazine
Product identifier
- Product name: N,N'-Dimethylpiperazine
- CBnumber: CB2664286
- CAS: 106-58-1
- EINECS Number: 203-412-0
- Synonyms: 1,4-dimethylpiperazine,N,N'-Dimethylpiperazine
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: N,N'-Dimethylpiperazine
- Synonyms: 1,4-dimethylpiperazine,N,N'-Dimethylpiperazine
- CAS: 106-58-1
- EC number: 203-412-0
- MF: C6H14N2
- MW: 114.19
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides Nitrogen oxides (NOx) Combustible.
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
Further information
Use water spray to cool unopened containers.
NFPA 704
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 4 | Will rapidly or completely vaporize at normal atmospheric pressure and temperature, or is readily dispersed in air and will burn readily. Includes pyrophoric substances. Flash point below room temperature at 22.8 °C (73 °F). (e.g. acetylene, propane, hydrogen gas) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapors accumulating to form explosive concentrations. Vapors can accumulate in low areas.
For personal protection see section 8.
Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container for disposal according to local / national regulations (see section 13).
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Advice on safe handling
Avoid contact with skin and eyes. Avoid inhalation of vapor or mist.
Advice on protection against fire and explosion
Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge.
Hygiene measures
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Storage conditions
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Store in cool place.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Personal protective equipmentTightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
Splash contact Material: Nitrile rubber
Minimum layer thickness: 0,4 mm Break through time: 101 min
Material tested:Camatril? (KCL 730 / Aldrich Z677442, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the EC approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Complete suit protecting against chemicals, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Where risk assessment shows air-purifying respirators are appropriate use a full- face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
Information on basic physicochemical properties
- Appearancecolorless liquid
- Odouramine-like
- Odour ThresholdNo data available
- pH11,4(undiluted)
- Melting point/freezing pointFreezing point: -0,7 °C - Regulation (EC) No. 440/2008, Annex, A.1
- Initial boiling point and boiling range131 - 132 °C at 1.000 hPa - lit.
- Flash point20 °C - Regulation (EC) No. 440/2008, Annex, A.9
- Evaporation rateNo data available
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limits Upper explosion limit: 9,6 %(V) Lower explosion limit: 1,8 %(V)
- Vapour pressure 13,06 hPa at 20 °C - Regulation (EC) No. 440/2008, Annex, A.4
- Vapour density 4,1
- Relative density0,82 at 20 °C - Regulation (EC) No. 440/2008, Annex, A.3
- Water solubility1.000 g/l at 20 °C - Regulation (EC) No. 440/2008, Annex, A.6
- Partition coefficient: n-octanol/waterlog Pow: -0,26 at 20 °C - Regulation (EC) No. 440/2008, Annex, A.8 - Bioaccumulation is not expected.
- Autoignition temperatureNo data available
- Decomposition temperatureNo data available
- ViscosityViscosity, kinematic: 0,88 mm2/s at 20 °C0,69 mm2/s at 40 °C Viscosity, dynamic: No data available
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
Other safety information
Surface tension 70,7 mN/m at 1g/l at 20 °C
-
Surface tension
Dissociation constant 9,78 at 20 °C
-
OECD Test Guideline 112
Relative vapor density
4,1
Reactivity
No data available
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
No data available
Conditions to avoid
Heat, flames and sparks.
Incompatible materials
Strong oxidizing agents, Strong acids
Hazardous decomposition products
In the event of fire: see section 5
Information on toxicological effects
Acute toxicityRemarks:
(ECHA)
LD50 Dermal - Rabbit - male and female - 3.000 mg/kg (OECD Test Guideline 402)
Remarks:
(ECHA)
Result: Corrosive after 1 to 4 hours of exposure - 24 h (OECD Test Guideline 404)
Remarks:
(ECHA)
Result: Irreversible effects on the eye - 1 s (OECD Test Guideline 405)
Remarks:
(ECHA)
Causes serious eye damage.
Result: Does not cause skin sensitization. (OECD Test Guideline 406)
Remarks:
(ECHA)
Buehler Test - Guinea pig
Result: Does not cause skin sensitization. (OECD Test Guideline 406)
Remarks:
(ECHA)
Result: negative Remarks:
(ECHA)
Toxicity
static test EC50 - Daphnia magna (Water flea) - > 100 mg/l - 48 h (Directive 67/548/EEC, Annex V, C.2.)
(OECD Test Guideline 201)
static test NOEC - Pseudokirchneriella subcapitata (green algae) - 100 mg/l - 72 h
(OECD Test Guideline 201)
Persistence and degradability
Biodegradability aerobic - Exposure time 28 d
Result: 5,6 % - Not readily biodegradable. (OECD Test Guideline 301C)
Bioaccumulative potential
Mobility in soil
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
Harmful to aquatic life.
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Waste material must be disposed of in accordance with the Directive on waste 2008/98/EC as well as other national and local regulations. Leave chemicals in original containers. No mixing with other waste. Handle uncleaned containers like the product itself.
Contaminated packaging
Dispose of as unused product.
UN number
ADR/RID: 2924 IMDG: 2924 IATA: 2924
UN proper shipping name
ADR/RID: FLAMMABLE LIQUID, CORROSIVE, N.O.S. (1,4-dimethylpiperazine) IMDG: FLAMMABLE LIQUID, CORROSIVE, N.O.S. (1,4-dimethylpiperazine)
IATA: Flammable liquid, corrosive, n.o.s. (1,4-dimethylpiperazine)
Transport hazard class(es)
ADR/RID: 3 (8) IMDG: 3 (8) IATA: 3 (8)
Packaging group
ADR/RID: II IMDG: II IATA: II
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
No data available
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.